Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments

[1]  D. Selkoe,et al.  Identification of a stable fragment of the Alzheimer amyloid precursor containing the beta-protein in brain microvessels. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[2]  D. Selkoe,et al.  Processing of the amyloid protein precursor to potentially amyloidogenic derivatives. , 1992, Science.

[3]  S. Younkin,et al.  Potentially amyloidogenic, carboxyl-terminal derivatives of the amyloid protein precursor. , 1992, Science.

[4]  D. Selkoe,et al.  Cellular processing of β-amyloid precursor protein and the genesis of amyloid β-peptide , 1993, Cell.

[5]  I. Mellman,et al.  Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant , 1991, Cell.

[6]  R. Rosenberg,et al.  Increased release of an amyloidogenic C‐terminal Alzheimer amyloid precursor protein fragment from stressed PC‐12 cells , 1991, Journal of neuroscience research.

[7]  R. Bacallao,et al.  pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells , 1991, The Journal of cell biology.

[8]  M. Pericak-Vance,et al.  Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease , 1991, Nature.

[9]  T. Oltersdorf,et al.  Cleavage of amyloid beta peptide during constitutive processing of its precursor. , 1990, Science.

[10]  D. Price,et al.  Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing. , 1990, Science.

[11]  R. Neve,et al.  The Alzheimer amyloid precursor protein. Identification of a stable intermediate in the biosynthetic/degradative pathway. , 1990, The Journal of biological chemistry.

[12]  M. Brown,et al.  NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor. , 1990, The Journal of biological chemistry.

[13]  B. Storrie,et al.  Isolation of subcellular organelles. , 1990, Methods in enzymology.

[14]  R. Neve,et al.  The amyloid precursor protein is concentrated in neuronal lysosomes in normal and Alzheimer disease subjects , 1989, Experimental Neurology.

[15]  Andreas Weidemann,et al.  Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein , 1989, Cell.

[16]  M. Lisanti,et al.  Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[17]  D. Selkoe,et al.  Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[18]  S. Shiojiri,et al.  Novel precursor of Alzheimer's disease amyloid protein shows protease inhibitory activity , 1988, Nature.

[19]  L. Villa-komaroff,et al.  Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease , 1988, Nature.

[20]  B. Greenberg,et al.  A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors , 1988, Nature.

[21]  R. Salgia,et al.  Degradation and regurgitation of extracellular proteins by cultured mouse peritoneal macrophages and baby hamster kidney fibroblasts. Kinetic evidence that the transfer of proteins to lysosomes is not irreversible. , 1987, The Journal of biological chemistry.

[22]  K. Grzeschik,et al.  The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor , 1987, Nature.

[23]  J. Folkman,et al.  HUMAN VASCULAR ENDOTHELIAL CELLS IN CULTURE , 1974, The Journal of cell biology.

[24]  E. Weibel,et al.  NEW CYTOPLASMIC COMPONENTS IN ARTERIAL ENDOTHELIA , 1964, The Journal of cell biology.