Activation of naïve CD4 T cells by anti-CD3 reveals an important role for Fyn in Lck-mediated signaling.
暂无分享,去创建一个
[1] J. Bluestone,et al. The Src Family Kinase Fyn Mediates Signals Induced by TCR Antagonists1 , 2002, The Journal of Immunology.
[2] K. Grebe,et al. Enumeration, Phenotyping, and Identification of Activation Events in Conjugates Between T cells and Antigen-Presenting Cells by Flow Cytometry , 2002, Science's STKE.
[3] S. Levin,et al. Regulation of Fyn Through Translocation of Activated Lck into Lipid Rafts , 2003, The Journal of experimental medicine.
[4] Michael F Denny,et al. Differential T-Cell Antigen Receptor Signaling Mediated by the Src Family Kinases Lck and Fyn , 2000, Molecular and Cellular Biology.
[5] Jianzhu Chen,et al. Homeostatic T cell proliferation in a T cell-dendritic cell coculture system , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[6] P. Rabinovitch,et al. Heterogeneity among T cells in intracellular free calcium responses after mitogen stimulation with PHA or anti-CD3. Simultaneous use of indo-1 and immunofluorescence with flow cytometry. , 1986, Journal of immunology.
[7] R. Klausner,et al. Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[8] R. Perlmutter,et al. Defective T cell receptor signaling in mice lacking the thymic isoform of p59 fyn , 1992, Cell.
[9] M. Croft,et al. Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells. , 1994, Journal of immunology.
[10] S. Lev,et al. Tyrosine Phosphorylation of Pyk2 Is Selectively Regulated by Fyn During TCR Signaling , 1997, The Journal of experimental medicine.
[11] H. Grey,et al. The minimal number of antigen‐major histocompatibility complex class II complexes required for activation of naive and primed T cells , 1997, European journal of immunology.
[12] M. Meier-Schellersheim,et al. Spontaneous proliferation, a response of naive CD4 T cells determined by the diversity of the memory cell repertoire. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[13] P. Stein,et al. The Src Family Tyrosine Kinase Fyn Regulates Natural Killer T Cell Development , 1999, The Journal of experimental medicine.
[14] H. Grey,et al. Differential T cell signaling induced by antagonist peptide-MHC complexes and the associated phenotypic responses. , 1997, Journal of immunology.
[15] K. Siminovitch,et al. Fyn and PTP-PEST–mediated Regulation of Wiskott-Aldrich Syndrome Protein (WASp) Tyrosine Phosphorylation Is Required for Coupling T Cell Antigen Receptor Engagement to WASp Effector Function and T Cell Activation , 2004, The Journal of experimental medicine.
[16] S. Hedrick,et al. Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition. , 1992, Journal of immunology.
[17] Graça Raposo,et al. Antigen-dependent and -independent Ca2+ Responses Triggered in T Cells by Dendritic Cells Compared with B Cells , 1998, The Journal of experimental medicine.
[18] T. Yagi,et al. Cutting Edge: Fyn Is Essential for Tyrosine Phosphorylation of Csk-Binding Protein/Phosphoprotein Associated with Glycolipid-Enriched Microdomains in Lipid Rafts in Resting T Cells1 , 2002, The Journal of Immunology.
[19] A. Wakeham,et al. Profound block in thymocyte development in mice lacking p56lck , 1992, Nature.
[20] P. Hogan,et al. T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFAT1 , 1996, Molecular and cellular biology.
[21] H. Grey,et al. TCR antagonist peptides induce formation of APC‐T cell conjugates and activate a Rac signaling pathway , 2000, European journal of immunology.
[22] Dan R. Littman,et al. Signal transduction by lymphocyte antigen receptors , 1994, Cell.
[23] L. Tuosto,et al. Organization of plasma membrane functional rafts upon T cell activation , 2001, European journal of immunology.
[24] P. Stein,et al. pp59 fyn mutant mice display differential signaling in thymocytes and peripheral T cells , 1992, Cell.
[25] L. Tuosto,et al. Fyn and ZAP-70 Are Required for Vav Phosphorylation in T Cells Stimulated by Antigen-presenting Cells* , 1998, The Journal of Biological Chemistry.
[26] C. Rudd,et al. FYN-T-FYB-SLP-76 Interactions Define a T-cell Receptor ζ/CD3-mediated Tyrosine Phosphorylation Pathway That Up-regulates Interleukin 2 Transcription in T-cells* , 1999, The Journal of Biological Chemistry.
[27] O. Utting,et al. T cells expressing receptors of different affinity for antigen ligands reveal a unique role for p59fyn in T cell development and optimal stimulation of T cells by antigen. , 1998, Journal of immunology.
[28] H. Grey,et al. T-cell receptor antagonists induce Vav phosphorylation by selective activation of Fyn kinase. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[29] H. Macdonald,et al. Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice. , 1999, Journal of immunology.
[30] Christopher C. Goodnow,et al. Differential activation of transcription factors induced by Ca2+ response amplitude and duration , 1997, Nature.