Computer applications to biochemical kinetics.

INTRODUCTION . . . • . . . . . • . . • . . • • • . . • . . . . . . . . . . . • . . • . • • . . . . . . . • • . . • . • . . . • . • ApPLICATION TO BIOCHEMICAL SYSTEMS . . • . . • • • • • . • • . • • • • • . • . • • • • • • . . . • . • . Glycolysis and related pathways . Control of blood glucose , . . . . . . . . . . . . . . . . . . . . . Mitochondrial systems . C ompartmentation studies . Optimation studies . Equilibrium studies . Protein synthesis . Miscellaneous systems . THEORETICAL . . . . • . . . • . • • . • • • • • • • • . • . • . • . . . • . . • • • . . • • • . • • . . . . • . • . . . . . . . . . Theorems derived with computers , .. . Biochemical oscillations . Enzyme kinetics . Allosteric control . Logical models . Input-otttput models . PROGRAMING, LANGUAGES AND METHODOLOGY . . . . . . . . . . . . . . . . . . . . . . . . . . • . . . Survey of compttter programs . Types of computers . Rate-law and matrix methods . Monte Carlo methods . . . . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . ' " . . . . . . ' " . . . o ptimation methods . Rand chemical equilibrium program . THE ApPLICATION OF COMPUTERS TO TEACHING OF BIOCHEMISTRY . GLOSSARY