Oral lipid-based formulations : enhancing the bioavailability of poorly water-soluable drugs

Currently Marketed Oral Lipid-Based Dosage Forms: Drug Products and Excipients. Lipid-Based Excipients for Oral Drug Delivery. Feasibility Assessment for Scaling Initial Prototype Lipid-Based Formulations to Initial Phase I/II Clinical Trial Batches. Materials, Process and Manufacturing Considerations for Lipid-Based Hard Capsule Formats. Liquid Self-Micro-Emulsifying Drug Delivery Systems (SMEDDS). Lipid-Based Isotropic Solutions: Design Considerations. Lipid-Based Self-emulsifying Solid Dispersions. Using Preclinical Data to Dictate Formulation Strategies for Poorly Water-Soluble Drugs. Physiological Processes Governing the Gastrointestinal Absorption of Lipids and Lipophilic Xenobiotics. Characterizing Release from Lipid-Based Formulations. Using In Vitro Dynamic Lipolysis Modeling as a Tool for Exploring IVIVC Relationships for Oral Lipid-Based Formulations. Case Study: Rational Development of Self-Emulsifying Formulations for Improving the Oral Bioavailability of Poorly Soluble, Lipophilic Drugs. Design and Development of Supersaturatable SEDDS (S-SEDDS) Formulations for Enhancing the Gastrointestinal Absorption of Poorly Soluble Drugs