Advances in the Surgical Correction of Presbyopia

Presbyopia is a ubiquitous visual disability of the aging eye, affecting an estimated 1.04 billion people globally. Given the prevalence, an increasing emphasis has been placed on the development of novel treatments for the surgical correction of presbyopia. In fact, more than half a dozen modalities are available, or in development, for the refractive surgeon to choose from depending on the patient’s needs. Worldwide, corneal inlays, presbyopia-correcting intraocular lenses (PCIOLs), conductive keratoplasty, presbyLASIK, intrastromal correction with the use of femtosecond technology (INTRACOR), and scleral modifications are available for this emerging subspecialty. The purpose of this review is to provide an overview of the surgical procedures and related devices currently in use or in development for the treatment of presbyopia.

[1]  Dan Z Reinstein,et al.  LASIK for hyperopic astigmatism and presbyopia using micro-monovision with the Carl Zeiss Meditec MEL80 platform. , 2009, Journal of refractive surgery.

[2]  Roberto Pineda,et al.  Accommodating Intraocular Lenses: Theory and Practice , 2010, International ophthalmology clinics.

[3]  Damien Gatinel,et al.  Design and qualification of a diffractive trifocal optical profile for intraocular lenses , 2011, Journal of cataract and refractive surgery.

[4]  J Stuart Cumming,et al.  Performance of the crystalens. , 2006, Journal of refractive surgery.

[5]  E. Manche,et al.  Conductive keratoplasty for the correction of low to moderate hyperopia: U.S. clinical trial 1-year results on 355 eyes. , 2002, Ophthalmology.

[6]  J. Alió,et al.  Conductive keratoplasty to correct residual hyperopia after cataract surgery , 2006, Journal of cataract and refractive surgery.

[7]  D. Lin,et al.  Two‐year results of conductive keratoplasty for the correction of low to moderate hyperopia , 2003, Journal of cataract and refractive surgery.

[8]  V. Portney,et al.  Synchrony dual‐optic accommodating intraocular lens: Part 1: Optical and biomechanical principles and design considerations , 2007, Journal of cataract and refractive surgery.

[9]  Orang Seyeddain,et al.  Refractive surgical correction of presbyopia with the AcuFocus small aperture corneal inlay: two-year follow-up. , 2010, Journal of refractive surgery.

[10]  George O Waring Correction of presbyopia with a small aperture corneal inlay. , 2011, Journal of refractive surgery.

[11]  Eduardo Tepichín,et al.  Objective quality of vision in presbyopic and non-presbyopic patients after pseudoaccommodative advanced surface ablation. , 2005, Journal of refractive surgery.

[12]  V. Portney,et al.  A dual optic accommodating foldable intraocular lens , 2003, The British journal of ophthalmology.

[13]  Michael J Lynn,et al.  Risk assessment for ectasia after corneal refractive surgery. , 2008, Ophthalmology.

[14]  Jason E Stahl,et al.  Conductive keratoplasty for presbyopia: 3-year results. , 2006, Journal of refractive surgery.

[15]  P. Asbell,et al.  Conductive keratoplasty for the correction of hyperopia. , 2001, Transactions of the American Ophthalmological Society.

[16]  R. Schachar Theoretical basis for the scleral expansion band procedure for surgical reversal of presbyopia [SRP] , 2000 .

[17]  Conductive keratoplasty for symptomatic presbyopia following monofocal intraocular lens implantation , 2011, Clinical & experimental ophthalmology.

[18]  Sudi Patel,et al.  Evidence for delayed presbyopia after photorefractive keratectomy for myopia. , 2006, Ophthalmology.

[19]  D R Sanders,et al.  Visual and refractive results of multifocal intraocular lenses. , 1991, Ophthalmology.

[20]  M. Knorz,et al.  Results of a European multicenter study of the True Vista bifocal intraocular lens , 1993, Journal of cataract and refractive surgery.

[21]  Colm McAlinden,et al.  Multifocal intraocular lens with a surface‐embedded near section: Short‐term clinical outcomes , 2011, Journal of cataract and refractive surgery.

[22]  Mike P Holzer,et al.  Visual outcomes and corneal changes after intrastromal femtosecond laser correction of presbyopia , 2012, Journal of cataract and refractive surgery.

[23]  I. Pallikaris,et al.  Long‐term results of conductive keratoplasty for low to moderate hyperopia , 2005, Journal of cataract and refractive surgery.

[24]  R. Steinert,et al.  A prospective comparative study of the AMO ARRAY zonal-progressive multifocal silicone intraocular lens and a monofocal intraocular lens. , 1999, Ophthalmology.

[25]  Mujtaba A. Qazi,et al.  Implantation of scleral expansion band segments for the treatment of presbyopia. , 2003, American journal of ophthalmology.

[26]  Peter Kim,et al.  Applications of the femtosecond laser in corneal refractive surgery , 2011, Current opinion in ophthalmology.

[27]  T. Tsuru,et al.  Simultaneous corneal inlay implantation and laser in situ keratomileusis for presbyopia in patients with hyperopia, myopia, or emmetropia: Six‐month results , 2012, Journal of cataract and refractive surgery.

[28]  D. Gatinel,et al.  Bilateral loss in the quality of vision associated with anterior corneal protrusion after hyperopic LASIK followed by intrastromal femtolaser-assisted incisions. , 2010, Journal of cataract and refractive surgery.

[29]  R. Lindstrom,et al.  Multifocal intraocular lenses , 1990, Journal of cataract and refractive surgery.

[30]  M. Tsilimbaris,et al.  Intraocular pressure measurements after conductive keratoplasty. , 2005, Journal of refractive surgery.

[31]  Angela Ehmer,et al.  Early outcomes of INTRACOR femtosecond laser treatment for presbyopia. , 2009, Journal of refractive surgery.

[32]  Y. Yamada,et al.  Accommodative intraocular lens with spring action. Part 1. Design and placement in an excised animal eye. , 1990, Ophthalmic surgery.

[33]  Jonathan J. Shuster,et al.  Implantation of scleral expansion band segments for the treatment of presbyopia 1 1 A complete list , 2002 .

[34]  Anthea M Burnett,et al.  Global vision impairment due to uncorrected presbyopia. , 2008, Archives of ophthalmology.

[35]  I. Pallikaris,et al.  Conductive keratoplasty: histological study of human corneas. , 2005, American journal of ophthalmology.

[36]  In-vivo architectural analysis of intrastromal incisions after INTRACOR surgery using Fourier-domain OCT and Scheimpflug imaging , 2011 .

[37]  Mark Packer,et al.  Clinical evaluation of the Crystalens AT‐45 accommodating intraocular lens: Results of the U.S. Food and Drug Administration clinical trial , 2006, Journal of cataract and refractive surgery.

[38]  P. Hersh Optics of conductive keratoplasty: implications for presbyopia management. , 2006, Transactions of the American Ophthalmological Society.

[39]  Jorge L Alió,et al.  Corneal multifocality with excimer laser for presbyopia correction , 2009, Current opinion in ophthalmology.

[40]  Silvania Y F Lau,et al.  Conductive keratoplasty to treat hyperopic overcorrection after LASIK for myopia. , 2011, Journal of refractive surgery.

[41]  R. Lindstrom,et al.  Food and Drug Administration study update. One-year results from 671 patients with the 3M multifocal intraocular lens. , 1993, Ophthalmology.

[42]  Richard H. Keates,et al.  Clinical results of the multifocal lens , 1987, Journal of cataract and refractive surgery.

[43]  Jihoon Kim,et al.  Dynamic impedance measurements during radio-frequency heating of cornea , 2002, IEEE Transactions on Biomedical Engineering.

[44]  Anna Simonetto,et al.  Correction of presbyopia in hyperopia with a center-distance, paracentral-near technique using the Technolas 217z platform. , 2008, Journal of refractive surgery.

[45]  M. A. Rosales,et al.  Advanced surface ablation for presbyopia using the Nidek EC-5000 laser. , 2004, Journal of refractive surgery.

[46]  Donald R Sanders,et al.  Functional reading acuity and performance: Comparison of 2 accommodating intraocular lenses , 2009, Journal of cataract and refractive surgery.

[47]  Corina van de Pol,et al.  Intracorneal inlay for the surgical correction of presbyopia , 2008, Journal of cataract and refractive surgery.

[48]  T. Tsuru,et al.  Conductive keratoplasty for the treatment of presbyopia: comparative study between post- and non-LASIK eyes , 2011, Clinical ophthalmology.

[49]  R. Schachar Theoretical basis for the scleral expansion band procedure for surgical reversal of presbyopia (SRP) , 2000, Comprehensive therapy.

[50]  T. Avitabile,et al.  Multifocal intra-ocular lenses , 2001, Current opinion in ophthalmology.

[51]  J. Davison,et al.  History and development of the apodized diffractive intraocular lens , 2006, Journal of cataract and refractive surgery.

[52]  S. Panagopoulou,et al.  Unilateral sulcus implantation of the crystalens HD. , 2012, Journal of refractive surgery.

[53]  R. Alarcón,et al.  Long‐term reading performance in patients with bilateral dual‐optic accommodating intraocular lenses , 2010, Journal of cataract and refractive surgery.

[54]  Sophia I Panagopoulou,et al.  Visual outcomes and safety of a small diameter intrastromal refractive inlay for the corneal compensation of presbyopia. , 2012, Journal of refractive surgery.

[55]  Jason E Stahl,et al.  Conductive keratoplasty for presbyopia: 1-year results. , 2007, Journal of refractive surgery.

[56]  L. Ruiz,et al.  Intrastromal correction of presbyopia using a femtosecond laser system. , 2009, Journal of refractive surgery.

[57]  Ike K Ahmed,et al.  Review of Presbyopic IOLs: Multifocal and Accommodating IOLs , 2012, International ophthalmology clinics.