A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity
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A. Skardal | Xuguang Zheng | P. Dedhia | H. Sivakumar | Priya H. Dedhia | J. Leight | Joshua Zent | Marco A. Rodriguez | Kylie G. Nairon | Katie Jones | Liudmila V. Popova
[1] A. Skardal,et al. αCT1 peptide sensitizes glioma cells to temozolomide in a glioblastoma organoid platform , 2022, Biotechnology and bioengineering.
[2] R. Strowd,et al. Immersion bioprinting of hyaluronan and collagen bioink-supported 3D patient-derived brain tumor organoids , 2022, Biomedical materials.
[3] A. Skardal,et al. Patient-Specific Sarcoma Organoids for Personalized Translational Research: Unification of the Operating Room with Rare Cancer Research and Clinical Implications , 2022, Annals of Surgical Oncology.
[4] S. Soker,et al. Exploiting maleimide-functionalized hyaluronan hydrogels to test cellular responses to physical and biochemical stimuli , 2021, Biomedical materials.
[5] S. Soker,et al. Engineering a thixotropic and biochemically tunable hyaluronan and collagen bioink for biofabrication of multiple tissue construct types , 2021, bioRxiv.
[6] G. Tiberio,et al. Efficacy of the EDP-M Scheme Plus Adjunctive Surgery in the Management of Patients with Advanced Adrenocortical Carcinoma: The Brescia Experience , 2020, Cancers.
[7] A. Skardal,et al. ASO Author Reflections: Co-cultured Lymph Node and Tumor Organoids as a Platform for the Creation of Adaptive Immunity and Predict Response to Immunotherapy , 2020, Annals of Surgical Oncology.
[8] S. Soker,et al. Development of a Colorectal Cancer 3D Micro-tumor Construct Platform From Cell Lines and Patient Tumor Biospecimens for Standard-of-Care and Experimental Drug Screening , 2020, Annals of Biomedical Engineering.
[9] C. Bishop,et al. Drug compound screening in single and integrated multi-organoid body-on-a-chip systems , 2020, Biofabrication.
[10] C. Bishop,et al. Probing prodrug metabolism and reciprocal toxicity with an integrated and humanized multi-tissue organ-on-a-chip platform. , 2020, Acta biomaterialia.
[11] Julio Aleman,et al. Immersion Bioprinting of Tumor Organoids in Multi-Well Plates for Increasing Chemotherapy Screening Throughput , 2020, Micromachines.
[12] L. Miller,et al. Model of Patient-Specific Immune-Enhanced Organoids for Immunotherapy Screening: Feasibility Study , 2019, Annals of Surgical Oncology.
[13] A. Skardal,et al. A mechanically robust thixotropic collagen and hyaluronic acid bioink supplemented with gelatin nanoparticles , 2019 .
[14] O. Straume,et al. Are 90% of deaths from cancer caused by metastases? , 2019, Cancer medicine.
[15] J. Leight,et al. High-Throughput Three-Dimensional Hydrogel Cell Encapsulation Assay for Measuring Matrix Metalloproteinase Activity. , 2019, Assay and drug development technologies.
[16] L. Miller,et al. Pleural Effusion Aspirate for use in 3D Lung Cancer Modeling and Chemotherapy Screening. , 2019, ACS biomaterials science & engineering.
[17] Shay Soker,et al. 3D bioprinting for high-throughput screening: Drug screening, disease modeling, and precision medicine applications. , 2019, Applied physics reviews.
[18] J. Leight,et al. Measuring Global Cellular Matrix Metalloproteinase and Metabolic Activity in 3D Hydrogels. , 2019, Journal of visualized experiments : JoVE.
[19] A. Skardal,et al. A multi-site metastasis-on-a-chip microphysiological system for assessing metastatic preference of cancer cells. , 2018, Biotechnology and bioengineering.
[20] A. Skardal,et al. Appendiceal Cancer Patient-Specific Tumor Organoid Model for Predicting Chemotherapy Efficacy Prior to Initiation of Treatment: A Feasibility Study , 2018, Annals of Surgical Oncology.
[21] Shay Soker,et al. Optimization of collagen type I-hyaluronan hybrid bioink for 3D bioprinted liver microenvironments , 2018, Biofabrication.
[22] Eric Baudin,et al. European Society of Endocrinology Clinical Practice Guidelines on the Management of Adrenocortical Carcinoma in Adults, in collaboration with the European Network for the Study of Adrenal Tumors. , 2018, European journal of endocrinology.
[23] P. Romagnoli,et al. Human fetal adrenal cells retain age‐related stem‐ and endocrine‐differentiation potential in culture , 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[24] C. Bishop,et al. Environmental Toxin Screening Using Human-Derived 3D Bioengineered Liver and Cardiac Organoids , 2018, Front. Public Health.
[25] A. Skardal,et al. In vitro patient-derived 3D mesothelioma tumor organoids facilitate patient-centric therapeutic screening , 2018, Scientific Reports.
[26] Kenneth L. Jones,et al. Development of new preclinical models to advance adrenocortical carcinoma research. , 2018, Endocrine-related cancer.
[27] A. Gopalan,et al. Complete Responses to Mitotane in Metastatic Adrenocortical Carcinoma-A New Look at an Old Drug. , 2017, The oncologist.
[28] Ali Khademhosseini,et al. Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform , 2017, Scientific Reports.
[29] Li-Hsin Han,et al. Modeling Physiological Events in 2D vs. 3D Cell Culture. , 2017, Physiology.
[30] O. Klein,et al. In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development , 2017, Development.
[31] Christine Unger,et al. Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT–mTOR–S6K signaling and drug responses , 2017, Journal of Cell Science.
[32] Alyssa J. Miller,et al. A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids , 2016, eLife.
[33] S. Soker,et al. A reductionist metastasis‐on‐a‐chip platform for in vitro tumor progression modeling and drug screening , 2016, Biotechnology and bioengineering.
[34] Hans Clevers,et al. Modeling Development and Disease with Organoids , 2016, Cell.
[35] Jason R Spence,et al. Organoid Models of Human Gastrointestinal Development and Disease. , 2016, Gastroenterology.
[36] Charles Swanton,et al. Metastasis as an evolutionary process , 2016, Science.
[37] Anthony Atala,et al. A hydrogel bioink toolkit for mimicking native tissue biochemical and mechanical properties in bioprinted tissue constructs. , 2015, Acta biomaterialia.
[38] A. Rosenwald,et al. Mitotane Inhibits Sterol-O-Acyl Transferase 1 Triggering Lipid-Mediated Endoplasmic Reticulum Stress and Apoptosis in Adrenocortical Carcinoma Cells. , 2015, Endocrinology.
[39] H. Sasano,et al. Adrenocortical carcinoma: review of the pathologic features, production of adrenal steroids, and molecular pathogenesis. , 2015, Endocrinology and metabolism clinics of North America.
[40] B. Fingleton,et al. Moving targets: Emerging roles for MMPs in cancer progression and metastasis. , 2015, Matrix biology : journal of the International Society for Matrix Biology.
[41] T. Mukohara,et al. Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer. , 2015, Oncology reports.
[42] T. Choueiri,et al. Linsitinib (OSI-906) versus placebo for patients with locally advanced or metastatic adrenocortical carcinoma: a double-blind, randomised, phase 3 study. , 2015, The Lancet. Oncology.
[43] C. Rodman,et al. Liver-Tumor Hybrid Organoids for Modeling Tumor Growth and Drug Response In Vitro , 2015, Annals of Biomedical Engineering.
[44] Vicky M. Avery,et al. Advanced Cell Culture Techniques for Cancer Drug Discovery , 2014, Biology.
[45] K. Anseth,et al. Direct measurement of matrix metalloproteinase activity in 3D cellular microenvironments using a fluorogenic peptide substrate. , 2013, Biomaterials.
[46] P. Jagodziński,et al. The effect of mitotane on viability, steroidogenesis and gene expression in NCI‑H295R adrenocortical cells. , 2013, Molecular medicine reports.
[47] Anthony Atala,et al. Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function. , 2012, Biomaterials.
[48] W. Rainey,et al. Human adrenocortical carcinoma cell lines , 2012, Molecular and Cellular Endocrinology.
[49] Michael R. Kennedy,et al. The effects of ACTH on steroid metabolomic profiles in human adrenal cells. , 2011, The Journal of endocrinology.
[50] J. Bertherat,et al. Transcriptome analysis reveals that p53 and {beta}-catenin alterations occur in a group of aggressive adrenocortical cancers. , 2010, Cancer research.
[51] F. Beuschlein,et al. High diagnostic and prognostic value of steroidogenic factor-1 expression in adrenal tumors. , 2010, The Journal of clinical endocrinology and metabolism.
[52] L. Kunz-Schughart,et al. Multicellular tumor spheroids: an underestimated tool is catching up again. , 2010, Journal of biotechnology.
[53] J. Dietl,et al. Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature , 2009, BMC Cancer.
[54] V. Toscano,et al. Mitotane increases the radiotherapy inhibitory effect and induces G2-arrest in combined treatment on both H295R and SW13 adrenocortical cell lines. , 2008, Endocrine-related cancer.
[55] Kenneth M. Yamada,et al. Modeling Tissue Morphogenesis and Cancer in 3D , 2007, Cell.
[56] M. Papotti,et al. Matrix metalloproteinase type 2 expression in malignant adrenocortical tumors: diagnostic and prognostic significance in a series of 50 adrenocortical carcinomas , 2006, Modern Pathology.
[57] S. Roman,et al. Adrenocortical carcinoma , 2006, Current opinion in oncology.
[58] J. Bertherat,et al. Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors. , 2005, Cancer research.
[59] B. Schimmer,et al. Adrenocortical cell lines , 2004, Molecular and Cellular Endocrinology.
[60] D. Talbot,et al. A phase I and pharmacological study of the matrix metalloproteinase inhibitor BB-3644 in patients with solid tumours , 2004, British Journal of Cancer.
[61] M. Jordá,et al. Melan A (A103) Is Expressed in Adrenocortical Neoplasms but Not in Renal Cell and Hepatocellular Carcinomas , 2003, Applied immunohistochemistry & molecular morphology : AIMM.
[62] Paul G Gauger,et al. Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis. , 2003, The American journal of pathology.
[63] E. Baudin,et al. Molecular markers and long-term recurrences in a large cohort of patients with sporadic adrenocortical tumors. , 2001, Cancer research.
[64] P. Heikkilä,et al. Expression of inhibin alpha in adrenocortical tumours reflects the hormonal status of the neoplasm. , 2000, The Journal of endocrinology.
[65] A. Mcnicol,et al. The expression of inhibin/activin subunits in the human adrenal cortex and its tumours. , 1999, The Journal of endocrinology.
[66] P. Maxwell,et al. Immunohistochemical staining of normal, hyperplastic, and neoplastic adrenal cortex with a monoclonal antibody against alpha inhibin. , 1998, Journal of clinical pathology.
[67] T. Triche,et al. Establishment and characterization of a human adrenocortical carcinoma cell line that expresses multiple pathways of steroid biosynthesis. , 1990, Cancer research.
[68] Benjamin J Raphael,et al. Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. , 2016, Cancer cell.
[69] J. Thigpen. Combination Chemotherapy in Advanced Adrenocortical Carcinoma , 2012 .
[70] Yao-Tseng Chen,et al. Immunoreactivity for A103, an antibody to melan-A (Mart-1), in adrenocortical and other steroid tumors. , 1998, The American journal of surgical pathology.
[71] P. Heikkilä,et al. Expression of inhibin alpha in the human adrenal gland and adrenocortical tumors. , 1998, Endocrine research.