Use of urine samples as controls for treatment of a Chlamydia trachomatis infection.

Chlamydia trachomatis is themost common sexually transmitted bacterial pathogen worldwide. Because most infected individuals are asymptomatic, the actual number of reported cases represents only a fraction of the infected population. If left untreated, this silent infection can evolve, in women, into pelvic inflammatory disease or lead to infertility. Since the infection is easily and effectively treatable with antibiotics (e.g. doxycycline and azitromycin), detection and treatment of infected individuals is an important part of chlamydia control programs.

[1]  Mellisa L. Theodore,et al.  Comparison of Three Nucleic Acid Amplification Tests for Detection of Chlamydia trachomatis in Urine Specimens , 2004, Journal of Clinical Microbiology.

[2]  J. Schachter,et al.  Volume Effect on Sensitivity of Nucleic Acid Amplification Tests for Detection of Chlamydia trachomatis in Urine Specimens from Females , 2003, Journal of Clinical Microbiology.

[3]  L. Schouls,et al.  Comparison between the LCx Probe System and the COBAS AMPLICOR System for Detection of Chlamydia trachomatisand Neisseria gonorrhoeae Infections in Patients Attending a Clinic for Treatment of Sexually Transmitted Diseases in Amsterdam, The Netherlands , 2001, Journal of Clinical Microbiology.

[4]  J. Malkin,et al.  Note: Kinetics of Chlamydia trachomatis Clearance in Patients With Azithromycin, as Assessed by First Void Urine Testing by PCR and Transcription‐Mediated Amplification , 1998, Sexually transmitted diseases.

[5]  J. Walboomers,et al.  Monitoring of Chlamydia trachomatis infections after antibiotic treatment using RNA detection by nucleic acid sequence based amplification. , 1998, Molecular pathology : MP.

[6]  L. Wallace,et al.  Use of PCR in resolving diagnostic difficulties potentially caused by genetic variation of hepatitis B virus. , 1998, Journal of clinical pathology.

[7]  J. Walboomers,et al.  Comparison of different primer sets for detection of Chlamydia trachomatis by the polymerase chain reaction. , 1993, Journal of medical microbiology.

[8]  P. C. van Voorst Vader,et al.  Chlamydia trachomatis infection in a high-risk population: comparison of polymerase chain reaction and cell culture for diagnosis and follow-up , 1993, Journal of clinical microbiology.

[9]  W. Quint,et al.  Diagnostic value of the polymerase chain reaction for Chlamydia detection as determined in a follow-up study , 1991, Journal of clinical microbiology.