What Can Be Done to Screen Progressive Diseases Optimally

Abstract A stochastic model for a screening program is presented in which the natural history of the disease is assumed to progress through a set of stages before detection. A model of the whole process is developed to address the interaction of the disease process and screening process. The purpose of the model is to develop insight into the disease process and derive policies which are optimal relative to the particular objectives chosen.

[1]  L. Blumenson,et al.  A mathematical analysis of the growth and spread of breast cancer. , 1969, Biometrics.

[2]  T. Louis,et al.  Screening for the early detection of cancer— I. The temporal natural history of a progressive disease state , 1978 .

[3]  Marvin Zelen,et al.  On the theory of screening for chronic diseases , 1969 .

[4]  Morton Klein,et al.  Surveillance Schedules for Medical Examinations , 1974 .

[5]  Thomas A. Louis,et al.  Screening for the early detection of cancer— III. Estimation of disease natural history☆ , 1978 .

[6]  G. Linden,et al.  Neuroblastoma in childhood. , 1969, American journal of diseases of children.

[7]  S. Shapiro,et al.  Lead time in breast cancer detection and implications for periodicity of screening. , 1974, American journal of epidemiology.

[8]  D. Kodlin A note on the cost-benefit problem in screening for breast cancer. , 1972, Methods of information in medicine.

[9]  T. Louis,et al.  Screening for the early detection of cancer- II. The impact of screening on the natural history of the disease , 1978 .

[10]  M. Nesbit,et al.  The VMA test strip: a new tool for mass screening, diagnosis, and management of catecholamine-secreting tumors. , 1972, Journal of pediatric surgery.

[11]  Hau L. Lee,et al.  Mass Screening Models for Contagious Diseases with No Latent Period , 1988, Oper. Res..

[12]  Philip C. Prorok,et al.  The theory of periodic screening I: Lead time and proportion detected , 1976, Advances in Applied Probability.

[13]  T. Lincoln,et al.  A Statistical Evaluation of Recurrent Medical Examinations , 1964 .

[14]  Gregory K. Miller,et al.  Elements of Applied Stochastic Processes , 1972 .

[15]  N. Breslow,et al.  Statistical estimation of prognosis for children with neuroblastoma. , 1971, Cancer research.

[16]  A. Evans,et al.  A proposed staging for children with neuroblastoma. Children's cancer study group A , 1971, Cancer.

[17]  William P. Pierskalla,et al.  Optimal Mass Screening under Constant and Threshold Test Reliabilities. , 1977 .

[18]  Rice Dp,et al.  Estimating the cost of illness. , 1967 .

[19]  S. Shapiro,et al.  Lead time gained by diagnostic screening for breast cancer. , 1968, Journal of the National Cancer Institute.

[20]  P C Prorok,et al.  Screening for the early detection of cancer. , 1986, Cancer investigation.

[21]  C. Koop,et al.  Diagnosis and treatment of neuroblastoma. , 1976, Pediatric clinics of North America.