Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
暂无分享,去创建一个
Virginia E. Papaioannou | S. Zeitlin | A. Efstratiadis | V. Papaioannou | D. Chapman | Jeh-Ping Liu | Scott Zeitlin | Argiris Efstratiadis | Deborah L. Chapman | Jeh-Ping Liu | D. L. Chapman
[1] R. Durbin,et al. Structure and expression of the Huntington's disease gene: Evidence against simple inactivation due to an expanded CAG repeat , 1994, Somatic cell and molecular genetics.
[2] Christopher A Ross,et al. Widespread expression of Huntington's disease gene (IT15) protein product , 1995, Neuron.
[3] Michael H. L. Snow,et al. Control of Embryonic Growth Rate and Fetal Size in Mammals , 1986 .
[4] J. Rossant,et al. fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. , 1994, Genes & development.
[5] M. Hayden,et al. A CCG repeat polymorphism adjacent to the CAG repeat in the Huntington disease gene: implications for diagnostic accuracy and predictive testing. , 1994, Human molecular genetics.
[6] R. Myers,et al. Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the protein. , 1995, Human molecular genetics.
[7] R. Richards,et al. Dynamic mutations on the move. , 1993, Journal of medical genetics.
[8] C A Ross,et al. Correlation between the onset age of Huntington's disease and length of the trinucleotide repeat in IT-15. , 1993, Human molecular genetics.
[9] R. Albin,et al. Genetics and molecular biology of Huntington's disease , 1995, Trends in Neurosciences.
[10] B. Hogan,et al. Manipulating the mouse embryo: A laboratory manual , 1986 .
[11] M. Hansen,et al. A method to isolate DNA from small archival tissue samples for p53 gene analysis , 1993, Human mutation.
[12] Mario R. Capecchi,et al. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development , 1990, Nature.
[13] D. Green,et al. Dicing with death: dissecting the components of the apoptosis machinery. , 1994, Trends in biochemical sciences.
[14] D. Borchelt,et al. Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from an antiapoptotic gene to a proapoptotic gene: studies in yeast and neural cells. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[15] A. Copp,et al. Death before birth: clues from gene knockouts and mutations. , 1995, Trends in genetics : TIG.
[16] Leo J. Fleishman,et al. Ultraviolet vision in lizards , 1993, Nature.
[17] D. Harrison,et al. Cell death in health and disease: the biology and regulation of apoptosis. , 1995, Seminars in cancer biology.
[18] Mario R. Capecchi,et al. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes , 1988, Nature.
[19] M. Capecchi,et al. Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus. , 1994, Genes & development.
[20] M. MacDonald,et al. Huntington's disease gene: Regional and cellular expression in brain of normal and affected individuals , 1995, Annals of neurology.
[21] A. Bradley. Production and analysis of chimeric mice , 1987 .
[22] J. Darnell,et al. Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. , 1994, Genes & development.
[23] G. Eguchi,et al. Cell lineage analysis of the primitive and visceral endoderm of mouse embryos cultured in vitro. , 1987, Cell Differentiation.
[24] E. Robertson. Teratocarcinomas and embryonic stem cells : a practical approach , 1987 .
[25] J. Penney,et al. Trinucleotide repeat length instability and age of onset in Huntington's disease , 1993, Nature Genetics.
[26] F. Squitieri,et al. Molecular analysis of juvenile Huntington disease: the major influence on (CAG)n repeat length is the sex of the affected parent. , 1993, Human molecular genetics.
[27] R. Carraway,et al. Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons , 1995, Neuron.
[28] S. Rusconi,et al. Transcriptional activation modulated by homopolymeric glutamine and proline stretches. , 1994, Science.
[29] R. Roos,et al. Characterization and localization of the Huntington disease gene product. , 1993, Human molecular genetics.
[30] Hugh A. Carithers,et al. Human Growth: A Comprehensive Treatise , 1987 .
[31] S. Lewis,et al. The developmental analysis of an embryonic lethal (C6H) in the mouse. , 1976, Journal of embryology and experimental morphology.
[32] M. Raff,et al. Social controls on cell survival and cell death , 1992, Nature.
[33] J. Baker,et al. Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r) , 1993, Cell.
[34] J. Rommens,et al. Sequence of the murine Huntington disease gene: evidence for conservation, alternate splicing and polymorphism in a triplet (CCG) repeat [corrected]. , 1994, Human molecular genetics.
[35] D. Steindler,et al. DNA End Labeling (TUNEL) in Huntington's Disease and Other Neuropathological Conditions , 1995, Experimental Neurology.
[36] T. Magnuson,et al. The albino deletion complex and early postimplantation survival in the mouse. , 1988, Development.
[37] Manish S. Shah,et al. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes , 1993, Cell.
[38] J. Penney,et al. The functional anatomy of basal ganglia disorders , 1989, Trends in Neurosciences.
[39] S. Folstein,et al. Huntington's disease gene (IT15) is widely expressed in human and rat tissues , 1993, Neuron.
[40] T. Knudsen,et al. Activation of apoptosis in early mouse embryos by 2'-deoxyadenosine exposure. , 1994, Teratology.
[41] M. MacDonald,et al. Mouse Huntington's disease gene homolog (Hdh) , 1994, Somatic cell and molecular genetics.
[42] P. Leder,et al. Murine FGFR-1 is required for early postimplantation growth and axial organization. , 1994, Genes & development.
[43] W. Jollie. Development, morphology, and function of the yolk-sac placenta of laboratory rodents. , 1990, Teratology.
[44] H. Steller,et al. Programmed cell death during Drosophila embryogenesis. , 1993, Development.
[45] C. Portera-Cailliau,et al. Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[46] R. Albin,et al. Widespread expression of the human and rat Huntington's disease gene in brain and nonneural tissues , 1993, Nature Genetics.
[47] R. Poelmann. Differential mitosis and degeneration patterns in relation to the alterations in the shape of the embryonic ectoderm of early post-implantation mouse embryos. , 1980, Journal of embryology and experimental morphology.
[48] M. Snow,et al. Is compensatory growth a complicating factor in mouse teratology? , 1979, Nature.
[49] S. Ben‐Sasson,et al. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation , 1992, The Journal of cell biology.
[50] Paul W Goldberg,et al. A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats. , 1994, The New England journal of medicine.
[51] C. Wheeler,et al. Sample preparation and PCR amplification from paraffin-embedded tissues. , 1994, PCR methods and applications.
[52] A. Joyner,et al. Inactivation of the mouse Huntington's disease gene homolog Hdh. , 1995, Science.
[53] S. Floresco,et al. Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes , 1995, Cell.
[54] E. Hirsch,et al. Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form , 1995, Nature Genetics.
[55] Robert I. Richards,et al. Dynamic mutations: A new class of mutations causing human disease , 1992, Cell.
[56] R. Harland,et al. In situ hybridization: an improved whole-mount method for Xenopus embryos. , 1991, Methods in cell biology.
[57] M. Snow. Growth and its control in early mammalian development. , 1981, British medical bulletin.