P482: Reliable monitoring of respiration rate with reflectance-mode photoplethysmography

s of Poster Presentations / Clinical Neurophysiology 125, Supplement 1 (2014) S1–S339 S177 mentation of sleep. Melatonin secretion was lower for patients with worse sleep, although biorhythm was visible in all but one patient. PSG with R&K analysis proved to be time-consuming and cumbersome, while the use of tandem mass spectrometry resulted in high throughput with excellent accuracy. Conclusions: Taking the limited scope of this pilot into account, worsening characteristics of sleep seem to coincide with loss of circadian rhythm. Currently, the availability of materials and the time-consuming analysis of PSG recordings are the main limiting factors of the study of sleep in the ICU. Automated, objective measures of quality and quantity of sleep are currently being validated in ICU and non-ICU patients, using only single channel EEG data. P478 Prediction of good and poor outcome in comatose patients after cardiac arrest: the utility of early EEG/SEP recordings during therapeutic hypothermia M. Spalletti1, R. Carrai1,2, A. Comanducci1, C. Cossu1, S. Gabbanini1, A. Peris3, G. Gensini2,4, A. Grippo1,2, A. Amantini1,2 1AOU Careggi, Neurophysiopathology, Florence, Italy; 2IRCCS Don Gnocchi, Neurologic Rehabilitation Unit, Florence, Italy; 3AOU Careggi, ICU Emergency, Florence, Italy; 4AOU Careggi, Heart-Vessels, Florence, Italy Question: Somatosensory evoked potentials (SEPs) are a reliable predictor of poor outcome in comatose patients after cardiac arrest (CA) treated with therapeutic hypotermia (TH). The role of EEG has been recently emphasized during early phase after CA. Our aim is to evaluate the prognostic value of EEG and SEPs in post-anoxic comatose patients within 12hs and 24hs from cardiac arrest (CA). Methods: Comatose patients after CA treated with TH were included. EEG and SEPs were recorded within 12hs and 24hs after CA. EEG was classified into discontinous (low voltage, isoelectric, burst suppression) and continuous (other patterns except epileptiform). SEPs were dicotomized into “bilaterally absent” (BA) and “present”. Neurologic outcome was evaluated at 6 months by GOS: “awakening” (GOS 3-5) was considered good outcome. Results: EEG and SEPs were recorded in 72 patients: 25 of these were studied within 12hs from CA. All patients with a continuous EEG pattern at 12hs awakened. The same EEG pattern recorded at 24 hs was not always predictive of awakening. BA SEPs at 12hs predicted poor outcome and were associated to discontinuous EEG patterns. Continuous EEG pattern was always associated with present SEPs. Conclusion: Combined early EEG/SEPs recordings are a useful tool for reliable prognostication both of good and poor outcome in comatose patients treated with TH. P479 Continuous EEG monitoring in neurointensive care. Organisation and assessment of impact M. Fabricius1, A. Sabers2, H. Hoegenhaven1, J. Brennum3, K. Moeller4, K. Hansen2, T.W. Kjaer1 1Rigshospitalet, Clinical neurophysiology, Copenhagen, Denmark; 2Rigshospitalet, Neurology, Copenhagen, Denmark; 3Rigshospitalet, Neurosurgery, Copenhagen, Denmark; 4Rigshospitalet, Neuroanaesthesiology,