TP53 mutations in newly diagnosed acute myeloid leukemia: Clinicomolecular characteristics, response to therapy, and outcomes
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Rashmi Kanagal-Shamanna | Koichi Takahashi | Jorge Cortes | Guillermo Garcia-Manero | Gautam Borthakur | Marina Konopleva | M. Konopleva | Z. Estrov | H. Kantarjian | G. Garcia-Manero | J. Cortes | K. Patel | T. Kadia | P. Jain | F. Ravandi | M. Andreef | Koichi Takahashi | G. Borthakur | E. Jabbour | N. Daver | C. Dinardo | S. Pierce | R. Kanagal-Shamanna | Elias Jabbour | Farhad Ravandi | Hagop M Kantarjian | Zeev Estrov | Preetesh Jain | Michael Andreef | Tapan M Kadia | Keyur Patel | Naval G Daver | Courtney Dinardo | Sherry Pierce | Naval G. Daver
[1] J. Radich,et al. FLT3, RAS, and TP53 mutations in elderly patients with acute myeloid leukemia. , 2001, Blood.
[2] L. Möllgård,et al. Chromosomal aberrations in 17p predict in vitro drug resistance and short overall survival in acute myeloid leukemia , 2008, Leukemia & lymphoma.
[3] N. Socci,et al. Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. , 2012, The New England journal of medicine.
[4] V. Rotter,et al. Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. , 2000, Cancer research.
[5] T. Naoe,et al. Prognostic value of p53 gene mutations and the product expression in de novo acute myeloid leukemia , 2000, European journal of haematology.
[6] P. Jeffrey,et al. Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. , 1994, Science.
[7] T. Soussi,et al. p53 mutation heterogeneity in cancer. , 2005, Biochemical and biophysical research communications.
[8] V. Rotter,et al. Mutant p53 protein expression interferes with p53-independent apoptotic pathways , 1998, Oncogene.
[9] H. Einsele,et al. TP53 mutation in patients with high‐risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation , 2016, British journal of haematology.
[10] Kerby Shedden,et al. Acquired genomic copy number aberrations and survival in adult acute myelogenous leukemia. , 2010, Blood.
[11] Sigrun M. Hjelle,et al. Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia , 2012, Oncogene.
[12] J. Downing,et al. Mouse models of human AML accurately predict chemotherapy response. , 2009, Genes & development.
[13] Michael B. Mann,et al. Mutant p53 accumulates in cycling and proliferating cells in the normal tissues of p53 R172H mutant mice , 2015, Oncotarget.
[14] Yun Zhang,et al. Mutant p53: Multiple Mechanisms Define Biologic Activity in Cancer , 2015, Front. Oncol..
[15] D. Christiansen,et al. Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis. , 2001, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[16] G. Ehninger,et al. The prognostic impact of 17p (p53) deletion in 2272 adults with acute myeloid leukemia , 2009, Leukemia.
[17] D. Christiansen,et al. Genetics of therapy-related myelodysplasia and acute myeloid leukemia , 2008, Leukemia.
[18] B. Ko,et al. TP53 mutations in de novo acute myeloid leukemia patients: longitudinal follow-ups show the mutation is stable during disease evolution , 2015, Blood Cancer Journal.
[19] Torsten Haferlach,et al. Acute myeloid leukemia with a complex aberrant karyotype is a distinct biological entity characterized by genomic imbalances and a specific gene expression profile , 2005, Genes, chromosomes & cancer.
[20] Ken H. Young,et al. Mutational profiling of therapy-related myelodysplastic syndromes and acute myeloid leukemia by next generation sequencing, a comparison with de novo diseases. , 2015, Leukemia research.
[21] M. Hollstein,et al. p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM , 2007, Nature Cell Biology.
[22] J. Aurelius,et al. Immunotherapeutic strategies for relapse control in acute myeloid leukemia. , 2013, Blood reviews.
[23] R. Hills,et al. TP53 gene mutation is frequent in patients with acute myeloid leukemia and complex karyotype, and is associated with very poor prognosis , 2009, Leukemia.
[24] L. Medeiros,et al. Cytogenetic findings in blastoid mantle cell lymphoma. , 2003, Human pathology.
[25] Magali Olivier,et al. TP53 mutations in human cancers: origins, consequences, and clinical use. , 2010, Cold Spring Harbor perspectives in biology.
[26] N. Emi,et al. TP53 mutations in older adults with acute myeloid leukemia , 2016, International Journal of Hematology.
[27] S. Fröhling,et al. TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome. , 2012, Blood.