Bone defect animal models for testing efficacy of bone substitute biomaterials
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L. Qin | Long Li | Y. Lai | Ye Li | Xin-Luan Wang | Shukui Chen
[1] T. Yoshii,et al. Local injection of lovastatin in biodegradable polyurethane scaffolds enhances bone regeneration in a critical‐sized segmental defect in rat femora , 2014, Journal of tissue engineering and regenerative medicine.
[2] L. Tan,et al. An animal experimental study of porous magnesium scaffold degradation and osteogenesis , 2014, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
[3] Jason A Inzana,et al. 3D printing of composite calcium phosphate and collagen scaffolds for bone regeneration. , 2014, Biomaterials.
[4] E. Botchwey,et al. Delivery of S1P receptor-targeted drugs via biodegradable polymer scaffolds enhances bone regeneration in a critical size cranial defect. , 2014, Journal of biomedical materials research. Part A.
[5] James F. Griffith,et al. Comparative study of poly (lactic-co-glycolic acid)/tricalcium phosphate scaffolds incorporated or coated with osteogenic growth factors for enhancement of bone regeneration , 2014 .
[6] Ming Li,et al. Tissue engineering scaffolds of mesoporous magnesium silicate and poly(ε-caprolactone)–poly(ethylene glycol)–poly(ε-caprolactone) composite , 2014, Journal of Materials Science: Materials in Medicine.
[7] Marcus Abboud,et al. Porous titanium granules in critical size defects of rabbit tibia with or without membranes , 2014, International Journal of Oral Science.
[8] K. Shakesheff,et al. Controlled release of BMP‐2 from a sintered polymer scaffold enhances bone repair in a mouse calvarial defect model , 2014, Journal of tissue engineering and regenerative medicine.
[9] Robert Geoffrey Richards,et al. AO Research Institute Davos within the AO Foundation: A model for translation of science to the clinics , 2013 .
[10] Jie Wei,et al. Preparation and osteogenic properties of magnesium calcium phosphate biocement scaffolds for bone regeneration , 2013 .
[11] Ángel E. Mercado-Pagán,et al. The effect of rhBMP-2 and PRP delivery by biodegradable β-tricalcium phosphate scaffolds on new bone formation in a non-through rabbit cranial defect model , 2013, Journal of Materials Science: Materials in Medicine.
[12] L. Strauss,et al. Evaluation of New Bone Formation in Normal and Osteoporotic Rats with a 3-mm Femur Defect: Functional Assessment with Dynamic PET-CT (dPET-CT) Using 2-Deoxy-2-[18F]Fluoro-d-glucose (18F-FDG) and 18F-Fluoride , 2013, Molecular Imaging and Biology.
[13] Stefan Rammelt,et al. Establishment of a femoral critical-size bone defect model in immunodeficient mice. , 2013, The Journal of surgical research.
[14] L. Qin,et al. PLGA/TCP composite scaffold incorporating bioactive phytomolecule icaritin for enhancement of bone defect repair in rabbits. , 2013, Acta biomaterialia.
[15] Y. Leng,et al. Exogenous phytoestrogenic molecule icaritin incorporated into a porous scaffold for enhancing bone defect repair , 2013, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[16] E. Schemitsch,et al. Expression of VEGF Gene Isoforms in a Rat Segmental Bone Defect Model Treated With EPCs , 2012, Journal of orthopaedic trauma.
[17] P. Marcorelles,et al. Mixture of hyaluronic acid, chondroitin 6 sulphate and dermatan sulphate used to completely regenerate bone in rat critical size defect model. , 2012, Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery.
[18] Q. Cai,et al. Osteoconductive effectiveness of bone graft derived from antler cancellous bone: an experimental study in the rabbit mandible defect model. , 2012, International journal of oral and maxillofacial surgery.
[19] C. -. Chen,et al. Bone healing response to a synthetic calcium sulfate/β-tricalcium phosphate graft material in a sheep vertebral body defect model , 2012, Journal of biomedical materials research. Part B, Applied biomaterials.
[20] A. Molenberg,et al. PEG matrix enables cell-mediated local BMP-2 gene delivery and increased bone formation in a porcine critical size defect model of craniofacial bone regeneration. , 2012, Clinical oral implants research.
[21] K. Takaoka,et al. Regenerative repair of bone defects with osteoinductive hydroxyapatite fabricated to match the defect and implanted with combined use of computer-aided design, computer-aided manufacturing, and computer-assisted surgery systems: a feasibility study in a canine model , 2012, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.
[22] R. Delgado-Ruiz,et al. Histomorphometric and mineral degradation study of Ossceram: a novel biphasic B-tricalcium phosphate, in critical size defects in rabbits. , 2012, Clinical oral implants research.
[23] H. Redl,et al. Compromised bone healing following spacer removal in a rat femoral defect model. , 2012, Acta physiologica Hungarica.
[24] R. Lanzman,et al. Quantitative assessment of bone defect healing by multidetector CT in a pig model , 2012, Skeletal Radiology.
[25] Wei Wang,et al. Effect of calcium citrate on bone integration in a rabbit femur defect model. , 2012, Asian Pacific journal of tropical medicine.
[26] C. Susin,et al. Exploratory study on the effect of osteoactivin on bone formation in the rat critical-size calvarial defect model. , 2012, Journal of periodontal research.
[27] Sanjay Kumar,et al. Mobilization of bone marrow mesenchymal stem cells in vivo augments bone healing in a mouse model of segmental bone defect. , 2012, Bone.
[28] I. Hussain,et al. Evaluation of Osteoconductive and Osteogenic Potential of a Dentin-Based Bone Substitute Using a Calvarial Defect Model , 2012, International journal of dentistry.
[29] D. Cho,et al. Repair of rabbit ulna segmental bone defect using freshly isolated adipose-derived stromal vascular fraction. , 2012, Cytotherapy.
[30] Gerald Antoch,et al. Cone beam CT in assessment of tibial bone defect healing: an animal study. , 2012, Academic radiology.
[31] Changsheng Liu,et al. Osteogenic evaluation of calcium/magnesium-doped mesoporous silica scaffold with incorporation of rhBMP-2 by synchrotron radiation-based μCT. , 2011, Biomaterials.
[32] D. Kaplan,et al. Critical-size calvarial bone defects healing in a mouse model with silk scaffolds and SATB2-modified iPSCs. , 2011, Biomaterials.
[33] M. H. Fernandes,et al. Rodent models in bone-related research: the relevance of calvarial defects in the assessment of bone regeneration strategies , 2011, Laboratory animals.
[34] G. Schneider,et al. Bone regeneration with glass ceramic implants and calcium phosphate cements in a rabbit cranial defect model , 2010, Journal of materials science. Materials in medicine.
[35] Je-Yong Choi,et al. A combination graft of low-molecular-weight silk fibroin with Choukroun platelet-rich fibrin for rabbit calvarial defect. , 2010, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.
[36] Fan Wu,et al. Hierarchically microporous/macroporous scaffold of magnesium-calcium phosphate for bone tissue regeneration. , 2010, Biomaterials.
[37] J. Luyten,et al. Evaluation of bone regeneration with an injectable, in situ polymerizable Pluronic F127 hydrogel derivative combined with autologous mesenchymal stem cells in a goat tibia defect model. , 2010, Tissue engineering. Part A.
[38] D. Hutmacher,et al. Establishment of a preclinical ovine model for tibial segmental bone defect repair by applying bone tissue engineering strategies. , 2010, Tissue engineering. Part B, Reviews.
[39] C. Susin,et al. The critical-size supraalveolar peri-implant defect model: reproducibility in histometric data acquisition of alveolar bone formation and osseointegration. , 2009, Journal of clinical periodontology.
[40] David F. Williams. On the nature of biomaterials. , 2009, Biomaterials.
[41] T. Bauer,et al. Evaluation of a silica-containing bone graft substitute in a vertebral defect model. , 2009, Journal of biomedical materials research. Part A.
[42] K. Kang,et al. Implantation of canine umbilical cord blood-derived mesenchymal stem cells mixed with beta-tricalcium phosphate enhances osteogenesis in bone defect model dogs , 2008, Journal of veterinary science.
[43] A. van Kampen,et al. Coralline hydroxyapatite is a suitable bone graft substitute in an intra-articular goat defect model. , 2008, Journal of biomedical materials research. Part B, Applied biomaterials.
[44] D. Yu,et al. Bone regeneration of critical calvarial defect in goat model by PLGA/TCP/rhBMP-2 scaffolds prepared by low-temperature rapid-prototyping technology. , 2008, International journal of oral and maxillofacial surgery.
[45] L. Qin,et al. Establishment of Steroid-Associated Osteonecrosis Rabbit Model , 2008 .
[46] J. Clements,et al. Treating segmental bone defects: a new technique. , 2008, The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons.
[47] J. Jansen,et al. Development and characterization of a rabbit alveolar bone nonhealing defect model. , 2008, Journal of Biomedical Materials Research. Part A.
[48] Yilin Cao,et al. Repair of goat tibial defects with bone marrow stromal cells and β-tricalcium phosphate , 2008, Journal of materials science. Materials in medicine.
[49] Seung-Yun Shin,et al. Bone Formation on the Apatite-coated Zirconia Porous Scaffolds within a Rabbit Calvarial Defect , 2008, Journal of biomaterials applications.
[50] N. Demertzis,et al. Reconstruction of tibia defects by ipsilateral vascularized fibula transposition , 2008, Archives of Orthopaedic and Trauma Surgery.
[51] D. Togawa,et al. Bone formation following OP‐1 implantation is improved by addition of autogenous bone marrow cells in a canine femur defect model , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[52] Z. Gugala,et al. New Approaches in the Treatment of Critical‐Size Segmental Defects in Long Bones , 2007 .
[53] David L. Kaplan,et al. BMP-silk composite matrices heal critically sized femoral defects. , 2007, Bone.
[54] David J Mooney,et al. Quantitative assessment of scaffold and growth factor‐mediated repair of critically sized bone defects , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[55] E. Willbold,et al. Biodegradable magnesium scaffolds: Part II: peri-implant bone remodeling. , 2007, Journal of biomedical materials research. Part A.
[56] G. Evans,et al. In vivo osteogenic potential of human adipose-derived stem cells/poly lactide-co-glycolic acid constructs for bone regeneration in a rat critical-sized calvarial defect model. , 2007, Tissue engineering.
[57] R. G. Richards,et al. Animal models for implant biomaterial research in bone: a review. , 2007, European cells & materials.
[58] Takaaki Tanaka,et al. Repair of segmental bone defects in rabbit tibiae using a complex of beta-tricalcium phosphate, type I collagen, and fibroblast growth factor-2. , 2006, Biomaterials.
[59] S. Gogolewski,et al. Mechanical and radiological assessment of the influence of rhTGFβ‐3 on bone regeneration in a segmental defect in the ovine tibia: Pilot study , 2006, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[60] Z. Gugala,et al. The efficacy of cylindrical titanium mesh cage for the reconstruction of a critical‐size canine segmental femoral diaphyseal defect , 2006, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[61] K. Schlegel,et al. The monocortical critical size bone defect as an alternative experimental model in testing bone substitute materials. , 2006, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.
[62] J. Griffith,et al. Multiple bioimaging modalities in evaluation of an experimental osteonecrosis induced by a combination of lipopolysaccharide and methylprednisolone , 2006, Bone.
[63] J. Wiltfang,et al. Bone regeneration in osseous defects using a resorbable nanoparticular hydroxyapatite. , 2005, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.
[64] M. Carstens,et al. In Situ Osteogenesis: Regeneration of 10-cm Mandibular Defect in Porcine Model Using Recombinant Human Bone Morphogenetic Protein-2 (rhBMP-2) and Helistat Absorbable Collagen Sponge , 2005, The Journal of craniofacial surgery.
[65] Marcus Abboud,et al. Bone graft versus BMP-7 in a critical size defect--cranioplasty in a growing infant model. , 2005, Bone.
[66] A. Ogose,et al. Bone formation and resorption of highly purified beta-tricalcium phosphate in the rat femoral condyle. , 2005, Biomaterials.
[67] Olivier Gauthier,et al. In vivo bone regeneration with injectable calcium phosphate biomaterial: a three-dimensional micro-computed tomographic, biomechanical and SEM study. , 2005, Biomaterials.
[68] K. Bachus,et al. Determining relevance of a weight-bearing ovine model for bone ingrowth assessment. , 2004, Journal of biomedical materials research. Part A.
[69] Michael A K Liebschner,et al. Biomechanical considerations of animal models used in tissue engineering of bone. , 2004, Biomaterials.
[70] Beat Hammer,et al. In vivo efficacy of bone-marrow-coated polycaprolactone scaffolds for the reconstruction of orbital defects in the pig. , 2003, Journal of biomedical materials research. Part B, Applied biomaterials.
[71] A. Malone. Bone in Clinical Orthopedics , 2003 .
[72] Peter Patka,et al. Healing of segmental bone defects with granular porous hydroxyapatite augmented with recombinant human osteogenic protein‐I or autologous bone marrow , 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[73] Koichiro Takahashi,et al. Bone regeneration by recombinant human bone morphogenetic protein-2 and a novel biodegradable carrier in a rabbit ulnar defect model. , 2003, Biomaterials.
[74] Y. Lanir,et al. Enhancement of bone defect healing in old rats by TGF-β and IGF-1 , 2002, Experimental Gerontology.
[75] S. W. Kim,et al. Development of biomaterials for gene therapy. , 2000, Molecular therapy : the journal of the American Society of Gene Therapy.
[76] F. Linde,et al. Properties of growing trabecular ovine bone. Part I: mechanical and physical properties. , 2000, The Journal of bone and joint surgery. British volume.
[77] A. van Lingen,et al. New segmental long bone defect model in sheep: Quantitative analysis of healing with dual energy X‐ray absorptiometry , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[78] C. Perry,et al. Bone repair techniques, bone graft, and bone graft substitutes. , 1999, Clinical orthopaedics and related research.
[79] S. Boonen,et al. Interspecies differences in bone composition, density, and quality: potential implications for in vivo bone research. , 1998, Endocrinology.
[80] G. Engh,et al. Treatment of Major Defects of Bone with Bulk Allografts and Stemmed Components during Total Knee Arthroplasty* , 1997, The Journal of bone and joint surgery. American volume.
[81] M. Chapman,et al. Treatment of Acute Fractures with a Collagen-Calcium Phosphate Graft Material. A Randomized Clinical Trial*† , 1997, The Journal of bone and joint surgery. American volume.
[82] I. Stockley,et al. Reconstruction of Massive Bone Defects with Allograft in Revision Total Knee Arthroplasty* , 1997, The Journal of bone and joint surgery. American volume.
[83] J. Wark,et al. The potential of sheep for the study of osteopenia: current status and comparison with other animal models. , 1995, Bone.
[84] R. A. Forster,et al. Alternatives to Autogenous Bone Graft: Efficacy and Indications , 1995, The Journal of the American Academy of Orthopaedic Surgeons.
[85] L. Mosekilde,et al. Calcium-restricted ovariectomized Sinclair S-1 minipigs: an animal model of osteopenia and trabecular plate perforation. , 1992, Bone.
[86] I. Stockley,et al. Allograft reconstruction in total knee arthroplasty. , 1992, The Journal of bone and joint surgery. British volume.
[87] V. Goldberg,et al. Distal femoral replacement with allograft/prosthetic reconstruction for treatment of supracondylar fractures in patients with total knee arthroplasty. , 1992, The Journal of arthroplasty.
[88] D. Raab,et al. A histomorphometric study of cortical bone activity during increased weight‐bearing exercise , 1991, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[89] A I Caplan,et al. Repair of bone defects with marrow cells and porous ceramic. Experiments in rats. , 1989, Acta orthopaedica Scandinavica.
[90] J. Kragstrup,et al. Compressive strength, ash weight, and volume of vertebral trabecular bone in experimental fluorosis in pigs , 1987, Calcified Tissue International.
[91] J O Hollinger,et al. The critical size defect as an experimental model for craniomandibulofacial nonunions. , 1986, Clinical orthopaedics and related research.
[92] L. Schweiberer,et al. Bone regeneration in animals and in man , 1981, Archives of orthopaedic and traumatic surgery.
[93] M. Campanacci,et al. Total resection of distal femur or proximal tibia for bone tumours. Autogenous bone grafts and arthrodesis in twenty-six cases. , 1979, The Journal of bone and joint surgery. British volume.
[94] R. Gunn. The Development of Bone , 1927 .
[95] S. Babu,et al. Strontium calcium phosphate for the repair of leporine (Oryctolagus cuniculus) ulna segmental defect. , 2013, Journal of biomedical materials research. Part A.
[96] B. Rovner,et al. A Randomized Clinical Trial , 2013 .
[97] P. Atkinson,et al. Design and assessment of a wrapped cylindrical Ca-P AZ31 Mg alloy for critical-size ulna defect repair. , 2012, Journal of biomedical materials research. Part B, Applied biomaterials.
[98] Genlin Wang,et al. A novel sheep vertebral bone defect model for injectable bioactive vertebral augmentation materials , 2011, Journal of materials science. Materials in medicine.
[99] W. Walsh,et al. Beta-TCP bone graft substitutes in a bilateral rabbit tibial defect model. , 2008, Biomaterials.
[100] 小牧 宏和. Repair of segmental bone defects in rabbit tibiae using a complex of β-tricalcium phosphate, type 1 collagen, and fibroblast growth factor-2 , 2007 .
[101] D. Muscolo,et al. Massive allograft use in orthopedic oncology. , 2006, The Orthopedic clinics of North America.
[102] 近藤 直樹. Bone formation and resorption of highly purified β-tricalcium phosphate in the rat femoral condyle , 2006 .
[103] G. Herrero-Beaumont,et al. Bone mineral measurements of subchondral and trabecular bone in healthy and osteoporotic rabbits , 2005, Skeletal Radiology.
[104] M. Kellomäki,et al. Inability of transforming growth factor-β1, combined with a bioabsorbable polymer paste, to promote healing of bone defects in the rat distal femur , 2001, Archives of Orthopaedic and Trauma Surgery.
[105] F. Linde,et al. PART I: MECHANICAL AND PHYSICAL PROPERTIES , 2000 .
[106] Yuehuei H. An,et al. Animal Models in Orthopaedic Research , 1999 .
[107] J D Mabrey,et al. An interspecies comparison of bone fracture properties. , 1998, Bio-medical materials and engineering.
[108] J. Buckwalter,et al. Use of animal models in musculoskeletal research. , 1998, The Iowa orthopaedic journal.
[109] M. Swindle,et al. Swine as models in experimental surgery. , 1988, Journal of investigative surgery : the official journal of the Academy of Surgical Research.
[110] L. Schweiberer,et al. A Contribution to Understanding the Relative Value of Animal Experiments to Human Pathophysiology , 1981 .