A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice

[1]  M. Harrington,et al.  Behavioral and neurochemical sources of variability of circadian period and phase: studies of circadian rhythms of npy-/- mice. , 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

[2]  Jacqueline N. Crawley,et al.  Mouse behavioral tasks relevant to autism: Phenotypes of 10 inbred strains , 2007, Behavioural Brain Research.

[3]  O. Ousley,et al.  Attention-deficit hyperactivity disorder symptoms in a clinic sample of children and adolescents with pervasive developmental disorders. , 2006, Journal of child and adolescent psychopharmacology.

[4]  S. Srinivasan,et al.  Glial-derived neurotrophic factor modulates enteric neuronal survival and proliferation through neuropeptide Y. , 2006, Gastroenterology.

[5]  Christoph Schmitz,et al.  The Developmental Neurobiology of Autism Spectrum Disorder , 2006, The Journal of Neuroscience.

[6]  Wei Zhang,et al.  Pten Regulates Neuronal Arborization and Social Interaction in Mice , 2006, Neuron.

[7]  W. Schulz-Schaeffer,et al.  Deletion of Cellular Prion Protein Results in Reduced Akt Activation, Enhanced Postischemic Caspase-3 Activation, and Exacerbation of Ischemic Brain Injury , 2006, Stroke.

[8]  Naoki Nitta,et al.  Reelin Deficiency and Displacement of Mature Neurons, But Not Neurogenesis, Underlie the Formation of Granule Cell Dispersion in the Epileptic Hippocampus , 2006, The Journal of Neuroscience.

[9]  S. Baker,et al.  Neuron‐specific enolase‐cre mouse line with cre activity in specific neuronal populations , 2006, Genesis.

[10]  H. Coon Current perspectives on the genetic analysis of autism , 2006, American journal of medical genetics. Part C, Seminars in medical genetics.

[11]  Junying Yuan,et al.  Pten deficiency activates distinct downstream signaling pathways in a tissue-specific manner. , 2006, Cancer research.

[12]  S. Moy,et al.  Mouse models of autism spectrum disorders: The challenge for behavioral genetics , 2006, American journal of medical genetics. Part C, Seminars in medical genetics.

[13]  M. Andriola,et al.  Autism and epilepsy: Cause, consequence, comorbidity, or coincidence? , 2005, Epilepsy & Behavior.

[14]  T. Hirota,et al.  Ser-557-phosphorylated mCRY2 Is Degraded upon Synergistic Phosphorylation by Glycogen Synthase Kinase-3β* , 2005, Journal of Biological Chemistry.

[15]  K. Miyazaki,et al.  A Role for Glycogen Synthase Kinase-3β in the Mammalian Circadian Clock* , 2005, Journal of Biological Chemistry.

[16]  K. Gadow,et al.  The presentation of anxiety in children with pervasive developmental disorders. , 2005, Journal of child and adolescent psychopharmacology.

[17]  M. Steriade Sleep, epilepsy and thalamic reticular inhibitory neurons , 2005, Trends in Neurosciences.

[18]  C Eng,et al.  Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations , 2005, Journal of Medical Genetics.

[19]  D. Gutmann,et al.  Pten Loss Causes Hypertrophy and Increased Proliferation of Astrocytes In vivo , 2004, Cancer Research.

[20]  G. Stores,et al.  Sleep patterns and sleep disorders in children with autistic spectrum disorders: insights using parent report and actigraphy , 2004, Developmental medicine and child neurology.

[21]  B. Malow Sleep disorders, epilepsy, and autism. , 2004, Mental retardation and developmental disabilities research reviews.

[22]  K. Fukunaga,et al.  Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase‐3 protein expression in the mouse suprachiasmatic nuclei , 2004, The European journal of neuroscience.

[23]  M. Merzenich,et al.  Model of autism: increased ratio of excitation/inhibition in key neural systems , 2003, Genes, brain, and behavior.

[24]  Ruth A. Carper,et al.  Evidence of brain overgrowth in the first year of life in autism. , 2003, JAMA.

[25]  L. Fu,et al.  The circadian clock: pacemaker and tumour suppressor , 2003, Nature Reviews Cancer.

[26]  L. Stewart,et al.  Temporal lobe seizures alter the amplitude and timing of rat behavioral rhythms , 2003, Epilepsy & Behavior.

[27]  M. Schachner,et al.  Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival , 2003, Molecular and Cellular Neuroscience.

[28]  R. Honomichl,et al.  Sleep Patterns of Children with Pervasive Developmental Disorders , 2002, Journal of autism and developmental disorders.

[29]  R. Tuchman,et al.  Epilepsy in autism , 2002, The Lancet Neurology.

[30]  N. Risch,et al.  On the twin risk in autism. , 2002, American journal of human genetics.

[31]  M. Mansukhani,et al.  Reduced expression of PTEN correlates with breast cancer progression. , 2002, Human pathology.

[32]  C. Eng,et al.  Protean PTEN: form and function. , 2002, American journal of human genetics.

[33]  M. Lewandowski,et al.  Effects of intergeniculate leaflet lesions on circadian rhythms in the mouse , 2002, Behavioural Brain Research.

[34]  T. Gibler,et al.  PLEIOTROPIC EFFECTS OF CRYPTOCHROMES 1 AND 2 ON FREE-RUNNING AND LIGHT-ENTRAINED MURINE CIRCADIAN RHYTHMS , 2002, Journal of neurogenetics.

[35]  T. Mak,et al.  Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease , 2001, Nature Genetics.

[36]  P. Burger,et al.  Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease , 2001, Nature Genetics.

[37]  A. Trumpp,et al.  Negative Regulation of Neural Stem/Progenitor Cell Proliferation by the Pten Tumor Suppressor Gene in Vivo , 2001, Science.

[38]  C. James,et al.  PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme. , 2001, Journal of the National Cancer Institute.

[39]  L. Hoefsloot,et al.  PTEN mutation in a family with Cowden syndrome and autism. , 2001, American journal of medical genetics.

[40]  M. W. Young,et al.  A Role for the Segment Polarity Gene shaggy/GSK-3 in the Drosophila Circadian Clock , 2001, Cell.

[41]  Mark Quigg,et al.  Circadian rhythms: interactions with seizures and epilepsy , 2000, Epilepsy Research.

[42]  R. Tuchman,et al.  Treatment of Seizure Disorders and EEG Abnormalities in Children with Autism Spectrum Disorders , 2000, Journal of autism and developmental disorders.

[43]  M. Holmes,et al.  Behavioral feedback regulation of circadian rhythm phase angle in light-dark entrained mice. , 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

[44]  A. Parmeggiani,et al.  Epilepsy in adolescents and young adults with autistic disorder , 2000, Brain and Development.

[45]  P. Guldberg,et al.  Mutation and allelic loss of the PTEN/MMAC1 gene in primary and metastatic melanoma biopsies. , 2000, The Journal of investigative dermatology.

[46]  Jon T. Willie,et al.  Narcolepsy in orexin Knockout Mice Molecular Genetics of Sleep Regulation , 1999, Cell.

[47]  J. Crawley Behavioral phenotyping of transgenic and knockout mice: experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests 1 Published on the World Wide Web on 2 December 1998. 1 , 1999, Brain Research.

[48]  D. V. Leenen,et al.  Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms , 1999, Nature.

[49]  C. Eng,et al.  Germline PTEN mutation in a family with Cowden syndrome and Bannayan-Riley-Ruvalcaba syndrome. , 1998, American journal of medical genetics.

[50]  B. Tonge,et al.  An investigation into sleep characteristics of children with autism and Asperger’s Disorder , 1998, Journal of paediatrics and child health.

[51]  José Luis de la Pompa,et al.  Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN , 1998, Cell.

[52]  N Dürmüller,et al.  Role of Thalamic and Cortical Neurons in Augmenting Responses and Self-Sustained Activity: Dual Intracellular Recordings In Vivo , 1998, The Journal of Neuroscience.

[53]  Tomohiko Maehama,et al.  The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate* , 1998, The Journal of Biological Chemistry.

[54]  L. Sundstrom,et al.  Granule cell dispersion is correlated with early epileptic events in human temporal lobe epilepsy , 1998, Journal of the Neurological Sciences.

[55]  S. Folstein,et al.  Macrocephaly in children and adults with autism. , 1997, Journal of the American Academy of Child and Adolescent Psychiatry.

[56]  P. Achermann,et al.  Altered circadian activity rhythms and sleep in mice devoid of prion protein , 1996, Nature.

[57]  P. Schwartzkroin,et al.  Role of the hippocampus in epilepsy , 1994, Hippocampus.

[58]  R. S. Sloviter,et al.  The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy , 1994, Annals of neurology.

[59]  T. Sejnowski,et al.  Thalamocortical oscillations in the sleeping and aroused brain. , 1993, Science.

[60]  Blaise F. D. Bourgeois,et al.  Pediatric Epilepsy: Diagnosis and Therapy , 1993 .

[61]  C. Houser Granule cell dispersion in the dentate gyrus of humans with temporal lobe epilepsy , 1990, Brain Research.

[62]  S. Reppert,et al.  Molecular analysis of mammalian circadian rhythms. , 2001, Annual review of physiology.