The Metabolism of Chemicals by the Lung

[1]  C. Wolf,et al.  Cytochrome p-450: localization in rabbit lung. , 1980, Science.

[2]  C. Harris,et al.  Metabolism of benzo[a]pyrene by cultured tracheobronchial tissues from mice, rats, hamsters, bovines and humans , 1980, International journal of cancer.

[3]  C. Wolf,et al.  The rabbit pulmonary monooxygenase system. Catalytic differences between two purified forms of cytochrome P-450 in the metabolism of benzo(a)pyrene. , 1979, The Journal of biological chemistry.

[4]  M. Boyd,et al.  In vivo studies on the relationship between target organ alkylation and the pulmonary toxicity of a chemically reactive metabolite of 4-ipomeanol. , 1978, The Journal of pharmacology and experimental therapeutics.

[5]  E. Miller Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address. , 1978, Cancer research.

[6]  C. Harris,et al.  Human pulmonary alveolar macrophages metabolise benzo(a)pyrene to proximate and ultimate mutagens , 1978, Nature.

[7]  M. Boyd Evidence for the Clara cell as a site of cytochrome P450-dependent mixed-function oxidase activity in lung , 1977, Nature.

[8]  J. Vane,et al.  Metabolic Functions of the Lung , 1977 .

[9]  C. Harris,et al.  Interindividual variation in binding of benzo[a]pyrene to DNA in cultured human bronchi. , 1976, Science.

[10]  G. Cohen,et al.  Benzo(a)pyren-3-yl hydrogen sulphate, a major ethyl acetate-extractable metabolite of benzo(a)pyrene in human, hamster and rat lung cultures. , 1976, Biochemical pharmacology.

[11]  A. Hewer,et al.  The involvement of a diol‐epoxide in the metabolic activation of benzo(a)pyrene in human bronchial mucosa and in mouse skin , 1976, International journal of cancer.

[12]  G. Hook,et al.  Pulmonary metabolism of xenobiotics. , 1976, Life sciences.

[13]  G. Cohen PULMONARY METABOLISM OF INHALED SUBSTANCES AND POSSIBLE RELATIONSHIP WITH CARCINOGENICITY AND TOXICITY , 1975 .

[14]  A. Hewer,et al.  Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide , 1974, Nature.

[15]  J. Vane,et al.  Pharmacokinetic function of the pulmonary circulation. , 1974, Physiological reviews.

[16]  E. A. Brown,et al.  THe localization, metabolism and effects of drugs and toxicants in lung. , 1974, Drug metabolism reviews.

[17]  T. E. Gram Comparative aspects of mixed function oxidation by lung and liver of rabbits. , 1973, Drug metabolism reviews.

[18]  G. Hook,et al.  Mixed-function oxidases and the alveolar macrophage. , 1972, Biochemical pharmacology.

[19]  L. Wattenberg Dietary modification of intestinal and pulmonary aryl hydrocarbon hydroxylase activity. , 1972, Toxicology and applied pharmacology.

[20]  T. Devereux,et al.  Developmental aspects of hepatic and extrahepatic drug-metabolizing enzyme systems: microsomal enzymes and components in rabbit liver and lung during the first month of life. , 1972, The Journal of pharmacology and experimental therapeutics.

[21]  G. Krishna,et al.  Metabolism of foreign compounds by alveolar macrophages of rabbits. , 1972, Biochemical and biophysical research communications.

[22]  L. Wattenberg,et al.  Tissue Distribution Studies of Polycyclic Hydrocarbon Hydroxylase Activity , 1971 .

[23]  R. T. Williams Detoxication mechanisms : the metabolism and detoxication of drugs, toxic substances and other organic compounds , 1959 .