Matrix solid-phase dispersion.

Matrix solid-phase dispersion (MSPD) is a patented process, first reported in 1989, for conducting simultaneous disruption and extraction of solid and semi-solid samples. MSPD permits complete fractionation of the sample matrix components as well as the ability to selectively elute a single compound or several classes of compounds from the same sample. The method has been applied to the isolation of drugs in food animal tissues but has also found wide application in the analysis of herbicides, pesticides and pollutants from animal tissues, fruits, vegetables and other matrices. The present article provides a review of MSPD applications in these and related fields and discusses the factors known to affect MSPD methods. Both the practical and theoretical aspects of MSPD are also presented.

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[31]  S. A. Barker HOW TO ANALYZE THOSE MESSY BIOLOGICAL SAMPLES : THIS NOVEL TECHNIQUE, CALLED MATRIX SOLID-PHASE DISPERSION, GREATLY SIMPLIFIES PREPARATION AND ANALYSI S OF TISSUE SAMPLES , 1993 .

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[33]  J. Sutra,et al.  Matrix solid-phase dispersion technique for the determination of moxidectin in bovine tissues. , 1996, The Analyst.

[34]  G. Font,et al.  Optimization of a matrix solid-phase dispersion method for the analysis of pesticide residues in vegetables. , 1996, Journal of chromatography. A.

[35]  Y. Picó,et al.  Comparison of octadecylsilica and graphitized carbon black as materials for solid-phase extraction of fungicide and insecticide residues from fruit and vegetables. , 1997, Journal of chromatography. A.

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[38]  M. Smyth,et al.  Comparison of matrix solid phase dispersion (MSPD) with a standard solvent extraction method for sulphamethazine in pork muscle using high performance liquid and thin layer chromatography. , 1994, Food additives and contaminants.

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[42]  J. Tolls,et al.  Extraction and isolation of linear alcohol ethoxylates from fish , 1999 .

[43]  F. Schenck Isolation and Quantification of Ivermectin in Bovine Milk by Matrix Solid Phase Dispersion (MSPD) Extraction and Liquid Chromatographic Determination , 1995 .

[44]  P. Toutain,et al.  Disposition of creatine kinase activity in dog plasma following intravenous and intramuscular injection of skeletal muscle homogenates. , 1995, Journal of veterinary pharmacology and therapeutics.

[45]  J. Henion,et al.  Multi-residue confirmation of aminoglycoside antibiotics and bovine kidney by ion spray high-performance liquid chromatography/tandem mass spectrometry. , 1994, Biological mass spectrometry.

[46]  M. O'keeffe,et al.  Application of the matrix solid phase dispersion technique for the determination of ivermectin residues in fish muscle tissue. , 1994, The Analyst.

[47]  J. Walsh,et al.  High-performance liquid chromatography of sulphonamides extracted from bovine and porcine muscle by solid-phase dispersion. , 1992, Journal of chromatography.

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[50]  F. Schenck,et al.  Screening procedure for organochlorine and organophosphorus pesticide residues in milk using matrix solid phase dispersion (MSPD) extraction and gas chromatographic determination. , 1995, Food additives and contaminants.

[51]  K. Kleinow,et al.  Matrix solid-phase dispersion isolation and liquid chromatographic determination of oxolinic acid in channel catfish (Ictalurus punctatus) muscle tissue , 1992 .

[52]  F. Schenck,et al.  Determination of Clorsulon Residues in Milk Using a Solid-Phase Extraction Cleanup and Liquid Chromatographic Determination , 1993 .

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[54]  Y. Picó,et al.  Analysis of pesticide residues in fruit and vegetables by matrix solid phase dispersion (MSPD) and different gas chromatography element-selective detectors , 1995 .