Anticomplement activity of isolated compounds from Artemisia montana

The study evaluated the anticomplement activity from isolated compounds from Artemisia montana (Nakai) Pamp. from South Korea on the classical pathway. In a previous work, A. montana (Nakai) Pamp. chloroform extracts showed inhibitory activity against complement system. The chromatographic separation of a chloroform chloride extract of A. montana (Nakai) Pamp. led to the isolation of four compounds. Their structures were characterized to be ezoartemin (1), yamayomoginin (2), ezomontanin (3) and 11,13-dihydroezomontanin (4) by spectroscopic data. This is the first report of anticomplement activity of isolated compounds from A. montana (Nakai) Pamp.

[1]  Eunhye Kim,et al.  Inhibition effects of the classical pathway complement of isolated compounds from Quercus glauca , 2011, Human & experimental toxicology.

[2]  Myong-Jo Kim,et al.  RETRACTED: Inhibition effects of the classical pathway complement of three Sorghum bicolor from South Korea , 2011, Immunopharmacology and immunotoxicology.

[3]  J. Choi,et al.  Extraction and identification of three major aldose reductase inhibitors from Artemisia montana. , 2011, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[4]  H. Moon,et al.  Anti‐complement activity of isolated compounds from the roots of Clerodendrum bungei Steud. , 2010, Phytotherapy research : PTR.

[5]  D. Song,et al.  Isolation and identification of antioxidant compounds from Ligularia fischeri. , 2010, Journal of food science.

[6]  Ren-bo An,et al.  Anti-complementary activity of protostane-type triterpenes fromAlismatis rhizoma , 2003, Archives of pharmacal research.

[7]  M. Ogundele.  Anti-complement activities of human breast-milk , 1999, Inflammation Research.

[8]  K. Ahn,et al.  Anti-complement activity of tiliroside from the flower buds of Magnolia fargesii. , 1998, Biological & pharmaceutical bulletin.

[9]  Mahabir P. Gupta,et al.  Complement-Inhibiting Properties of Apeiba tibourbou , 1993, Planta medica.

[10]  천상욱,et al.  Physiological Activity of Methanol Extracts from Ligularia fischeri and Their Hyperplasia Inhibition Activity of Cancer Cell , 2009 .

[11]  H. Kwon,et al.  Phytochemical constituents of Artemisia stolonifera. , 2001, Archives of pharmacal research.

[12]  M. Nagaki,et al.  Guaianolides from Artemisia montana , 1989 .