Vms1/Ankzf1 peptidyl-tRNA hydrolase releases nascent chains from stalled ribosomes

[1]  T. Cameron Waller,et al.  Sterol Oxidation Mediates Stress-Responsive Vms1 Translocation to Mitochondria. , 2017, Molecular cell.

[2]  F. Hartl,et al.  Cytosolic Protein Vms1 Links Ribosome Quality Control to Mitochondrial and Cellular Homeostasis , 2017, Cell.

[3]  C. Joazeiro.  Ribosomal Stalling During Translation: Providing Substrates for Ribosome-Associated Protein Quality Control. , 2017, Annual review of cell and developmental biology.

[4]  R. Deshaies,et al.  Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy , 2017, Proceedings of the National Academy of Sciences.

[5]  T. Rapoport,et al.  Molecular Mechanism of Substrate Processing by the Cdc48 ATPase Complex , 2017, Cell.

[6]  R. Green,et al.  Ribosome pausing, arrest and rescue in bacteria and eukaryotes , 2017, Philosophical Transactions of the Royal Society B: Biological Sciences.

[7]  Johannes Söding,et al.  The MPI bioinformatics Toolkit as an integrative platform for advanced protein sequence and structure analysis , 2016, Nucleic Acids Res..

[8]  M. Fromont-Racine,et al.  Rqc1 and Ltn1 Prevent C-terminal Alanine-Threonine Tail (CAT-tail)-induced Protein Aggregation by Efficient Recruitment of Cdc48 on Stalled 60S Subunits* , 2016, The Journal of Biological Chemistry.

[9]  F. Hartl,et al.  Failure of RQC machinery causes protein aggregation and proteotoxic stress , 2016, Nature.

[10]  J. Yates,et al.  The Rqc2/Tae2 subunit of the ribosome-associated quality control (RQC) complex marks ribosome-stalled nascent polypeptide chains for aggregation , 2016, eLife.

[11]  V. G. Panse,et al.  Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation , 2016, Cell.

[12]  Robert D. Finn,et al.  The Pfam protein families database: towards a more sustainable future , 2015, Nucleic Acids Res..

[13]  R. Hegde,et al.  The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon , 2015, Molecular biology of the cell.

[14]  Adam Frost,et al.  Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains , 2015, Science.

[15]  R. Hegde,et al.  Reconstitution of a Minimal Ribosome-Associated Ubiquitination Pathway with Purified Factors , 2014, Molecular cell.

[16]  R. Green,et al.  Cryoelectron Microscopic Structures of Eukaryotic Translation Termination Complexes Containing eRF1-eRF3 or eRF1-ABCE1 , 2014, Cell reports.

[17]  R. Hegde,et al.  Listerin-Dependent Nascent Protein Ubiquitination Relies on Ribosome Subunit Dissociation , 2013, Molecular cell.

[18]  Michael J. Sweredoski,et al.  Cand1 Promotes Assembly of New SCF Complexes through Dynamic Exchange of F Box Proteins , 2013, Cell.

[19]  M. Fromont-Racine,et al.  Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products , 2013, Proceedings of the National Academy of Sciences.

[20]  R. Deshaies,et al.  Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome , 2013, eLife.

[21]  Adam Frost,et al.  A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress , 2012, Cell.

[22]  R. Green,et al.  Kinetic analysis reveals the ordered coupling of translation termination and ribosome recycling in yeast , 2011, Proceedings of the National Academy of Sciences.

[23]  H. Schindelin,et al.  The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM) , 2011, The Journal of Biological Chemistry.

[24]  M. Bycroft,et al.  The General Definition of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM) Delineates a New Family of p97 Cofactors* , 2011, The Journal of Biological Chemistry.

[25]  Sebastian A. Wagner,et al.  A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles* , 2011, Molecular & Cellular Proteomics.

[26]  C. Joazeiro,et al.  Role of a ribosome-associated E3 ubiquitin ligase in protein quality control , 2010, Nature.

[27]  Ali Azizi,et al.  Chemical-genetic profile analysis of five inhibitory compounds in yeast , 2010, BMC chemical biology.

[28]  David Loakes,et al.  Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release , 2010, Proceedings of the National Academy of Sciences.

[29]  Paramvir S. Dehal,et al.  FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments , 2010, PloS one.

[30]  Sean R Eddy,et al.  A new generation of homology search tools based on probabilistic inference. , 2009, Genome informatics. International Conference on Genome Informatics.

[31]  Kazuki Saito,et al.  Structural insights into eRF3 and stop codon recognition by eRF1. , 2009, Genes & development.

[32]  Brian V. Jenkins,et al.  A mouse forward genetics screen identifies LISTERIN as an E3 ubiquitin ligase involved in neurodegeneration , 2009, Proceedings of the National Academy of Sciences.

[33]  E. Sonnhammer,et al.  Kalign2: high-performance multiple alignment of protein and nucleotide sequences allowing external features , 2008, Nucleic acids research.

[34]  Jianyu Zhu,et al.  Crystal structure of a translation termination complex formed with release factor RF2 , 2008, Proceedings of the National Academy of Sciences.

[35]  M. Mann,et al.  MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification , 2008, Nature Biotechnology.

[36]  Liisa Holm,et al.  Searching protein structure databases with DaliLite v.3 , 2008, Bioinform..

[37]  Christian Cole,et al.  The Jpred 3 secondary structure prediction server , 2008, Nucleic Acids Res..

[38]  T. Inada,et al.  Translation of the poly(A) tail plays crucial roles in nonstop mRNA surveillance via translation repression and protein destabilization by proteasome in yeast. , 2007, Genes & development.

[39]  Roy Parker,et al.  Exosome-Mediated Recognition and Degradation of mRNAs Lacking a Termination Codon , 2002, Science.

[40]  B. Séraphin,et al.  The tandem affinity purification (TAP) method: a general procedure of protein complex purification. , 2001, Methods.

[41]  D. Barford,et al.  The Crystal Structure of Human Eukaryotic Release Factor eRF1—Mechanism of Stop Codon Recognition and Peptidyl-tRNA Hydrolysis , 2000, Cell.

[42]  Gapped BLAST and PSI-BLAST: A new , 1997 .