Rabbit plasma metabolomic analysis of Nitroproston®: a multi target natural prostaglandin based-drug

[1]  I. I. Lyubimov,et al.  LC-MS/MS Identification and Structural Characterization of Main Biodegradation Products of Nitroproston - A Novel Prostaglandin-based Pharmaceutical Compound. , 2018, Drug Metabolism Letters.

[2]  Ó. Pozo,et al.  Targeting human urinary metabolome by LC-MS/MS: a review. , 2018, Bioanalysis.

[3]  Bofei Zhang,et al.  RaMP: A Comprehensive Relational Database of Metabolomics Pathways for Pathway Enrichment Analysis of Genes and Metabolites , 2018, Metabolites.

[4]  D. Fitzgerald,et al.  Question 1: Why do children still die from asthma? , 2018, Paediatric respiratory reviews.

[5]  G. Siuzdak,et al.  METLIN: A Technology Platform for Identifying Knowns and Unknowns. , 2018, Analytical chemistry.

[6]  S. Jee,et al.  Elevated Metabolites of Steroidogenesis and Amino Acid Metabolism in Preadolescent Female Children With High Urinary Bisphenol A Levels: A High-Resolution Metabolomics Study , 2017, Toxicological sciences : an official journal of the Society of Toxicology.

[7]  X. Nie,et al.  Metabolic profiling of asthma in mice and the interventional effects of SPA using liquid chromatography and Q-TOF mass spectrometry. , 2017, Molecular bioSystems.

[8]  Hui Wang,et al.  UHPLC-Q-TOF/MS based plasma metabolomics reveals the metabolic perturbations by manganese exposure in rat models. , 2017, Metallomics : integrated biometal science.

[9]  T. Asano,et al.  Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis , 2016, Mediators of inflammation.

[10]  Yonggui Pan,et al.  Pathway Analysis and Metabolites Identification by Metabolomics of Etiolation Substrate from Fresh-Cut Chinese Water Chestnut (Eleocharis tuberosa) , 2016, Molecules.

[11]  Fengguo Xu,et al.  Time-resolved metabolomics analysis of individual differences during the early stage of lipopolysaccharide-treated rats , 2016, Scientific Reports.

[12]  Massimo Broggini,et al.  Comparative metabolomics profiling of isogenic KRAS wild type and mutant NSCLC cells in vitro and in vivo , 2016, Scientific Reports.

[13]  W. Yao,et al.  Metabolic alterations in the sera of Chinese patients with mild persistent asthma: a GC-MS-based metabolomics analysis , 2015, Acta Pharmacologica Sinica.

[14]  J. McDunn,et al.  Metabolomic Endotype of Asthma , 2015, The Journal of Immunology.

[15]  Huwei Liu,et al.  Metabolomics Approach Reveals Integrated Metabolic Network Associated with Serotonin Deficiency , 2015, Scientific Reports.

[16]  Yue-qin Tang,et al.  A metabolomic and pharmacokinetic study on the mechanism underlying the lipid-lowering effect of orally administered berberine. , 2015, Molecular bioSystems.

[17]  R. Pawankar,et al.  Allergic diseases and asthma: a global public health concern and a call to action , 2014, The World Allergy Organization journal.

[18]  V·V·贝祖格鲁夫,et al.  Broncholytic drug on the basis of prostaglandin , 2013 .

[19]  Frank J. Gonzalez,et al.  LC-MS-based metabolomics in profiling of drug metabolism and bioactivation , 2012 .

[20]  H. Ressom,et al.  LC-MS-based metabolomics. , 2012, Molecular bioSystems.

[21]  M. Belvisi,et al.  Prostaglandin E2 mediates cough via the EP3 receptor: implications for future disease therapy. , 2009, American journal of respiratory and critical care medicine.

[22]  G. Saidel,et al.  Role of the malate-aspartate shuttle on the metabolic response to myocardial ischemia. , 2008, Journal of theoretical biology.

[23]  P. Barnes How corticosteroids control inflammation: Quintiles Prize Lecture 2005 , 2006, British journal of pharmacology.

[24]  S. Bornstein,et al.  The rapid release of corticosterone from the adrenal induced by ACTH is mediated by nitric oxide acting by prostaglandin E2 , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[25]  D. Kang,et al.  Uric acid as a mediator of endothelial dysfunction, inflammation, and vascular disease. , 2005, Seminars in nephrology.

[26]  A. Fernie,et al.  Metabolite profiling: from diagnostics to systems biology , 2004, Nature Reviews Molecular Cell Biology.

[27]  H. Jabbour,et al.  Expression, localization, and signaling of PGE(2) and EP2/EP4 receptors in human nonpregnant endometrium across the menstrual cycle. , 2001, The Journal of clinical endocrinology and metabolism.

[28]  J. Oates,et al.  EP(2) receptor mediates bronchodilation by PGE(2) in mice. , 2000, Journal of applied physiology.

[29]  M. Marletta,et al.  Guanylate cyclase and the .NO/cGMP signaling pathway. , 1999, Biochimica et biophysica acta.

[30]  L. Walch,et al.  Prostanoid receptors involved in the relaxation of human bronchial preparations , 1999, British journal of pharmacology.

[31]  W. J. Visek,et al.  Ammonia metabolism, urea cycle capacity and their biochemical assessment. , 2009, Nutrition reviews.

[32]  A. Lehninger,et al.  Occurrence of the malate-aspartate shuttle in various tumor types. , 1976, Cancer research.