The Chemical Reactivity of -Lactams, -Sultams and -Phospholactams
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[1] R. Wade,et al. pKa Calculations for class A β‐lactamases: Influence of substrate binding , 2008, Protein science : a publication of the Protein Society.
[2] Laurent Maveyraud,et al. X-ray Analysis of the NMC-A β-Lactamase at 1.64-Å Resolution, a Class A Carbapenemase with Broad Substrate Specificity* , 1998, The Journal of Biological Chemistry.
[3] L. Mourey,et al. Inhibition of the NMC-A β-Lactamase by a Penicillanic Acid Derivative and the Structural Bases for the Increase in Substrate Profile of This Antibiotic Resistance Enzyme , 1998 .
[4] R. Pratt,et al. Salicyloyl Cyclic Phosphate, a “Penicillin-Like” Inhibitor of β-Lactamases , 1998 .
[5] W. J. Stevens,et al. Acylation of β-Lactams by Class A β-Lactamase: An ab Initio Theoretical Study on the Effects of the Oxy-Anion Hole , 1997 .
[6] D. Chadwick,et al. Antibiotic resistance : origins, evolution, selection, and spread , 1997 .
[7] M. Ishiguro,et al. Modeling study on a hydrolytic mechanism of class A β-lactamases , 1996 .
[8] Laurent Maveyraud,et al. Crystal Structure of 6Alpha-Hydroxymethylpenicillanate Complexed to the Tem-1 Beta-Lactamase from Escherichia Coli: Evidence on the Mechanism of Action of a Novel Inhibitor Designed by a Computer-Aided Process , 1996 .
[9] I. Massova,et al. Design, Synthesis, and Evaluation of a Potent Mechanism-Based Inhibitor for the TEM .beta.-Lactamase with Implications for the Enzyme Mechanism , 1995 .
[10] M. Page,et al. Reactivity of β-lactams and phosphonamidates and reactions with β-lactamase , 1995 .
[11] K. Bush,et al. Biochemical comparison of imipenem, meropenem and biapenem: permeability, binding to penicillin-binding proteins, and stability to hydrolysis by beta-lactamases. , 1995, The Journal of antimicrobial chemotherapy.
[12] M. Karplus,et al. Hydrolysis rate difference between cyclic and acyclic phosphate esters: solvation versus strain , 1993 .
[13] C. Betzel,et al. Molecular structure of the acyl-enzyme intermediate in β-lactam hydrolysis at 1.7 Å resolution , 1992, Nature.
[14] R. Chabin,et al. Inhibition of human serine proteases by substituted 2-azetidinones. , 1992, Archives of biochemistry and biophysics.
[15] W. Hagmann,et al. Mechanism of inhibition of human leukocyte elastase by two cephalosporin derivatives. , 1992, Biochemistry.
[16] B. Santarsiero,et al. Distorted amides as models for activated peptide N-C(O) units. 3. Synthesis, hydrolytic profile, and molecular structure of 2,3,4,5-tetrahydro-2-oxo-1,5-propanobenzazepine , 1991 .
[17] A. J. Bennet,et al. Oxygen-18 exchange accompanying the basic hydrolysis of primary, secondary, and tertiary toluamides. 2. The importance of amine leaving abilities from the anionic tetrahedral intermediate , 1990 .
[18] R. Vessière,et al. SYNTHESIS AND REACTIONS OF -SULTAMS. A REVIEW , 1986 .
[19] K. Nakajima,et al. Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. Studies with peptide substrates related to the alpha 1-protease inhibitor reactive site. , 1979, The Journal of biological chemistry.
[20] D. Blow,et al. Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin , 1969, Nature.