Patient-derived explants, xenografts and organoids: 3-dimensional patient-relevant pre-clinical models in endometrial cancer.
暂无分享,去创建一个
C. Pritchard | M. MacFarlane | E. Moss | G. Miles | A. Collins | J. Wood
[1] C. Pritchard,et al. Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery , 2020, British Journal of Cancer.
[2] D. Timmerman,et al. Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening , 2019, Nature Cell Biology.
[3] P. Beale,et al. Phase 2 study of anastrozole in recurrent estrogen (ER)/progesterone (PR) positive endometrial cancer: The PARAGON trial - ANZGOG 0903. , 2019, Gynecologic oncology.
[4] F. Amant,et al. Development of Patient-Derived Tumor Xenograft Models. , 2018, Methods in molecular biology.
[5] C. Moiola,et al. Patient-Derived Xenograft Models for Endometrial Cancer Research , 2018, International journal of molecular sciences.
[6] C. Moiola,et al. Modeling Endometrial Cancer: Past, Present, and Future , 2018, International journal of molecular sciences.
[7] M. Hashizume,et al. Basement membrane destruction by pancreatic stellate cells leads to local invasion in pancreatic ductal adenocarcinoma. , 2018, Cancer letters.
[8] R. Wenham,et al. New therapies for advanced, recurrent, and metastatic endometrial cancers , 2017, Gynecologic Oncology Research and Practice.
[9] Rameen Beroukhim,et al. Patient-derived xenografts undergo murine-specific tumor evolution , 2017, Nature Genetics.
[10] Eric C. Huang,et al. The Use of Endometrial Cancer Patient–Derived Organoid Culture for Drug Sensitivity Testing Is Feasible , 2017, International Journal of Gynecologic Cancer.
[11] D. Moore,et al. Ex Vivo Explant Cultures of Non-Small Cell Lung Carcinoma Enable Evaluation of Primary Tumor Responses to Anticancer Therapy. , 2017, Cancer research.
[12] Bon-Kyoung Koo,et al. Long-term, hormone-responsive organoid cultures of human endometrium in a chemically-defined medium , 2017, Nature Cell Biology.
[13] T. Hope,et al. A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle , 2017, Nature Communications.
[14] P. Beale,et al. Phase II study of anastrozole in recurrent estrogen (ER) / progesterone (PR) positive endometrial cancer: The PARAGON trial—ANZGOG 0903. , 2016 .
[15] M. Inoue,et al. Drug screening and grouping by sensitivity with a panel of primary cultured cancer spheroids derived from endometrial cancer , 2016, Cancer science.
[16] D. Lambrechts,et al. Characterization of patient-derived tumor xenograft models of endometrial cancer for preclinical evaluation of targeted therapies. , 2015, Gynecologic oncology.
[17] G. Fleming. Second-Line Therapy for Endometrial Cancer: The Need for Better Options. , 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[18] Harikrishna Narasimhan,et al. Predicting clinical response to anticancer drugs using an ex vivo platform that captures tumour heterogeneity , 2015, Nature Communications.
[19] M. Spector,et al. Organoid Models of Human and Mouse Ductal Pancreatic Cancer , 2015, Cell.
[20] B. Weigelt,et al. Classification of endometrial carcinoma: more than two types. , 2014, The Lancet. Oncology.
[21] Mitsuaki Suzuki,et al. Applicability of the concept of "platinum sensitivity" to recurrent endometrial cancer: the SGSG-012/GOTIC-004/Intergroup study. , 2013, Gynecologic oncology.
[22] Steven J. M. Jones,et al. Integrated genomic characterization of endometrial carcinoma , 2013, Nature.
[23] Joseph M. Negri,et al. The role of tumour–stromal interactions in modifying drug response: challenges and opportunities , 2013, Nature Reviews Drug Discovery.
[24] Yong-Man Kim,et al. Progression-free survival is accurately predicted in patients treated with chemotherapy for epithelial ovarian cancer by the histoculture drug response assay in a prospective correlative clinical trial at a single institution. , 2013, Anticancer research.
[25] D. Miller,et al. Late-Breaking Abstract 1: Randomized phase III noninferiority trial of first line chemotherapy for metastatic or recurrent endometrial carcinoma: A Gynecologic Oncology Group study , 2012 .
[26] Jae-Hyun Park,et al. Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. , 2012, Cancer cell.
[27] John J. Evans,et al. The resistance of intracellular mediators to doxorubicin and cisplatin are distinct in 3D and 2D endometrial cancer , 2012, Journal of Translational Medicine.
[28] S. Schwartz,et al. Generation and characterization of orthotopic murine models for endometrial cancer , 2012, Clinical & Experimental Metastasis.
[29] A. Bryant,et al. Adjuvant chemotherapy for endometrial cancer after hysterectomy. , 2011, The Cochrane database of systematic reviews.
[30] P. Schwartz,et al. Critical evaluation of human endometrial explants as an ex vivo model system: a molecular approach. , 2011, Molecular human reproduction.
[31] A. Bryant,et al. Hormonal therapy in advanced or recurrent endometrial cancer. , 2010, The Cochrane database of systematic reviews.
[32] K. Moxley,et al. Endometrial Carcinoma: A Review of Chemotherapy, Drug Resistance, and the Search for New Agents , 2010, The oncologist.
[33] R. Casper,et al. Letrozole stimulates the growth of human endometrial explants cultured in three-dimensional fibrin matrix. , 2009, Fertility and sterility.
[34] P. Adegboyega,et al. Immunohistochemical profiling of cytokeratin expression by endometrial stroma sarcoma. , 2008, Human pathology.
[35] R. Kamps,et al. Effects of selective oestrogen receptor modulators on proliferation in tissue cultures of pre- and postmenopausal human endometrium , 2008, The Journal of Steroid Biochemistry and Molecular Biology.
[36] H. Jabbour,et al. F-prostanoid receptor regulation of fibroblast growth factor 2 signaling in endometrial adenocarcinoma cells. , 2007, Endocrinology.
[37] G. Fleming,et al. The relationship between histology and outcome in advanced and recurrent endometrial cancer patients participating in first-line chemotherapy trials: a Gynecologic Oncology Group study. , 2007, Gynecologic oncology.
[38] R. Casper,et al. Expression of Glycodelin and Cyclooxygenase‐2 in Human Endometrial Tissue Following Three‐dimensional Culture , 2007, American journal of reproductive immunology.
[39] X. Matías-Guiu,et al. Proteasome Inhibitors Induce Death but Activate NF-κB on Endometrial Carcinoma Cell Lines and Primary Culture Explants* , 2006, Journal of Biological Chemistry.
[40] Etienne Marbaix,et al. Response of matrix metalloproteinases and tissue inhibitors of metalloproteinases messenger ribonucleic acids to ovarian steroids in human endometrial explants mimics their gene- and phase-specific differential control in vivo. , 2005, The Journal of clinical endocrinology and metabolism.
[41] Patrick Neven,et al. Endometrial cancer , 2005, The Lancet.
[42] Sung Yeon Kim,et al. Formation of tamoxifen-DNA adducts in human endometrial explants exposed to α-hydroxytamoxifen , 2005 .
[43] R. Burger,et al. Phase III trial of doxorubicin plus cisplatin with or without paclitaxel plus filgrastim in advanced endometrial carcinoma: a Gynecologic Oncology Group Study. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[44] Minoti Sharma,et al. Biotransformation of tamoxifen in a human endometrial explant culture model. , 2003, Chemico-biological interactions.
[45] Jing Xu,et al. Three-dimensional in vitro culture of endometrial explants mimics the early stages of endometriosis. , 2003, Fertility and sterility.
[46] J. Olson,et al. Antioxidant inhibits tamoxifen-DNA adducts in endometrial explant culture. , 2003, Biochemical and biophysical research communications.
[47] V. Brunetto,et al. Goserelin Acetate as Treatment for Recurrent Endometrial Carcinoma: A Gynecologic Oncology Group Study , 2002, American journal of clinical oncology.
[48] K. Osteen,et al. Effect of TCDD exposure on CYP1A1 and CYP1B1 expression in explant cultures of human endometrium. , 2001, Toxicological sciences : an official journal of the Society of Toxicology.
[49] S. Koury,et al. Expression of AhR and ARNT mRNA in cultured human endometrial explants exposed to TCDD. , 2001, Toxicological sciences : an official journal of the Society of Toxicology.
[50] Joan L. Walker,et al. A phase II trial of anastrozole in advanced recurrent or persistent endometrial carcinoma: a Gynecologic Oncology Group study. , 2000, Gynecologic oncology.
[51] P. Courtoy,et al. The expression of interstitial collagenase in human endometrium is controlled by progesterone and by oestradiol and is related to menstruation. , 1995, The Biochemical journal.
[52] D. Decker,et al. Effects of Progestational Agents in Treatment of Endometrial Carcinoma , 1985, Obstetrics and gynecology.
[53] John J. Evans,et al. Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer. , 2013, Experimental cell research.
[54] F. Landoni,et al. Endometrial cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. , 2013, Annals of oncology : official journal of the European Society for Medical Oncology.
[55] H. Jabbour,et al. Interleukin-11 in endometrial adenocarcinoma is regulated by prostaglandin F2alpha-F-prostanoid receptor interaction via the calcium-calcineurin-nuclear factor of activated T cells pathway and negatively regulated by the regulator of calcineurin-1. , 2010, The American journal of pathology.
[56] J. Fiorica,et al. Phase II trial of alternating courses of megestrol acetate and tamoxifen in advanced endometrial carcinoma: a Gynecologic Oncology Group study. , 2004, Gynecologic oncology.
[57] A. Stavreus-Evers,et al. Development and characterization of an endometrial tissue culture system. , 2003, Reproductive biomedicine online.
[58] R. Schenken,et al. Whole explants of peritoneum and endometrium: a novel model of the early endometriosis lesion. , 1999, Fertility and sterility.