The locus coeruleus‐dorsal hippocampal CA1 pathway is involved in depression‐induced perioperative neurocognitive disorders in adult mice

Patients undergoing surgical anesthesia increasingly suffer from preoperative depression. Clinical studies have shown that depression is a risk factor for perioperative neurocognitive disorders (PNDs) in elder patients. However, the underlying mechanism, especially at the neural circuit level, remains poorly understood.

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