Myostatin expression in ventricular myocardium in a rat model of volume‐overload heart failure

Background  Mechanical stress increases myocardial myostatin expression. However, the expression of myostatin in chronic heart failure resulting from volume‐overload and after treatment with β‐blockers is little known. The authors hypothesize that myostatin plays a role in the failing myocardium because of volume‐overload.

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