Identification of Potential Vaccine and Drug Target Candidates by Expressed Sequence Tag Analysis and Immunoscreening of Onchocerca volvulus Larval cDNA Libraries
暂无分享,去创建一个
Steven A. Williams | Jing Liu | M. Lizotte-Waniewski | D. Guiliano | Wenhong Lu | S. Lustigman | S. Williams | Sara Lustigman | Wenhong Lu | Michelle Lizotte-Waniewski | Wilson Tawe | David B. Guiliano | Jing Liu | W. Tawe
[1] J. Daub,et al. Helminth genome analysis: the current status of the filarial and schistosome genome projects , 1999, Parasitology.
[2] A. Prince,et al. Onchocerca volvulus: immunization of chimpanzees with X-irradiated third-stage (L3) larvae. , 1992, Experimental parasitology.
[3] C. Mello,et al. Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos , 1997, Cell.
[4] J. McKerrow,et al. Molecular cloning and characterization of onchocystatin, a cysteine proteinase inhibitor of Onchocerca volvulus. , 1992, The Journal of biological chemistry.
[5] K. Nakai,et al. PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. , 1999, Trends in biochemical sciences.
[6] A. Lujan,et al. Onchocerciasis and immunity in humans: enhanced T cell responsiveness to parasite antigen in putatively immune individuals. , 1988, The Journal of infectious diseases.
[7] J. Wastling,et al. Cyclosporin A: antiparasite drug, modulator of the host-parasite relationship and immunosuppressant , 1992, Parasitology.
[8] D. Babin,et al. The isoinhibitors of chymotrypsin/elastase from Ascaris lumbricoides: the primary structure. , 1984, Archives of biochemistry and biophysics.
[9] P. Enyong,et al. Immunity to Onchocerciasis: Cells from Putatively Immune Individuals Produce Enhanced Levels of Interleukin-5, Gamma Interferon, and Granulocyte-Macrophage Colony-Stimulating Factor in Response to Onchocerca volvulus Larval and Male Worm Antigens , 2000, Infection and Immunity.
[10] J. Catmull,et al. Identification and characterisation of a novel repetitive antigen from Onchocerca spp. , 1994, Molecular and biochemical parasitology.
[11] J. Richer,et al. Dirofilaria immitis: proteases produced by third- and fourth-stage larvae. , 1992, Experimental parasitology.
[12] T. Meyer,et al. Protective immunity linked with a distinct developmental stage of a filarial parasite. , 1994, Journal of immunology.
[13] J. Lok,et al. Induction of protective immunity against larval Onchocerca volvulus in a mouse model. , 1993, The American journal of tropical medicine and hygiene.
[14] Tabbarra Kf. Book review: Onchocerciasis and its control, WHO technical report series no. 852, report of WHO expert committee on onchocerciasis control. , 1996 .
[15] A. Prince,et al. Identification and characterization of an Onchocerca volvulus cDNA clone encoding a highly immunogenic calponin-like protein. , 1994, Molecular and biochemical parasitology.
[16] T. Nutman,et al. Polymerase chain reaction-based diagnosis of Onchocerca volvulus infection: improved detection of patients with onchocerciasis. , 1994, The Journal of infectious diseases.
[17] E. Jorgensen,et al. The Caenorhabditis elegans unc-49 Locus Encodes Multiple Subunits of a Heteromultimeric GABA Receptor , 1999, The Journal of Neuroscience.
[18] P. Hotez,et al. A NOVEL PROTEIN ASSOCIATED WITH THE TRANSITION TO PARASITISM BY INFECTIVE HOOKWORM LARVAE , 1996 .
[19] B. Meyer,et al. The nuclear hormone receptor SEX-1 is an X-chromosome signal that determines nematode sex , 1998, Nature.
[20] K. Hoffmann,et al. Molecular Identification of a Schistosoma mansoni Tegumental Protein with Similarity to Cytoplasmic Dynein Light Chains* , 1996, The Journal of Biological Chemistry.
[21] S. Lustigman,et al. A novel developmentally regulated galectin of Onchocerca volvulus. , 2000, Molecular and biochemical parasitology.
[22] A highly conserved nematode protein folding operon in Caenorhabditis elegans and Caenorhabditis briggsae. , 1999, Gene.
[23] S. Hartmann,et al. A filarial cysteine protease inhibitor down‐regulates T cell proliferation and enhances interleukin‐10 production , 1997, European journal of immunology.
[24] M. Selkirk,et al. Resistance of filarial nematode parasites to oxidative stress. , 1998, International journal for parasitology.
[25] A. Kern,et al. Acanthocheilonema viteae: vaccination of jirds with irradiation-attenuated stage-3 larvae and with exported larval antigens. , 1991, Experimental parasitology.
[26] J. E. Rall,et al. Kostrouchova, M., Krause, M., Kostrouch, Z. & Rall, J.E. CHR3: a Caenorhabditis elegans orphan nuclear hormone receptor required for proper epidermal development and molting. Development 125, 1617-1626 , 1998 .
[27] M. Krause,et al. CHR3: a Caenorhabditis elegans orphan nuclear hormone receptor required for proper epidermal development and molting. , 1998, Development.
[28] Andrew Smith. Genome sequence of the nematode C-elegans: A platform for investigating biology , 1998 .
[29] J. Culotti,et al. daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans. , 1998, Development.
[30] S. Williams. Deep within the filarial genome: progress of the filarial genome project. , 1999, Parasitology today.
[31] T R Bürglin,et al. Caenorhabditis elegans as a model for parasitic nematodes. , 1998, International journal for parasitology.
[32] C. Wang. Parasite enzymes as potential targets for antiparasitic chemotherapy. , 1984, Journal of medicinal chemistry.
[33] H. Kolbe,et al. Characterization of a schistosome T cell-stimulating antigen (Sm10) associated with protective immunity in humans. , 1997, Molecular and biochemical parasitology.
[34] M. Qasim,et al. Expression and characterization of elastase inhibitors from the ascarid nematodes Anisakis simplex and Ascaris suum. , 1999, Molecular and biochemical parasitology.
[35] A. Fire,et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans , 1998, Nature.
[36] S. Lustigman,et al. Characterization of an Onchocerca volvulus L3-specific larval antigen, Ov-ALT-1. , 1998, Molecular and biochemical parasitology.
[37] P. Hotez,et al. Cloning and Characterization of Ancylostoma-secreted Protein , 1996, The Journal of Biological Chemistry.
[38] M. M. Wong,et al. Brugia pahangi: identification and characterization of an aminopeptidase associated with larval molting. , 1993, Experimental parasitology.
[39] K. Curtis,et al. Molecular characterization of a parasite antigen in sera from onchocerciasis patients that is immunologically cross-reactive with human keratin. , 1995, The Journal of infectious diseases.
[40] R. Lucius,et al. Acanthocheilonema viteae: characterization of a molt-associated excretory/secretory 18-kDa protein. , 1999, Experimental parasitology.
[41] J. Donelson,et al. Construction of Onchocerca volvulus cDNA libraries and partial characterization of the cDNA for a major antigen. , 1988, Molecular and biochemical parasitology.
[42] E. Vegeto,et al. Nuclear Hormone Receptors as Targets for New Drug Discovery , 1993, Nature Biotechnology.
[43] K. Ray,et al. Cytoplasmic dynein (ddlc1) mutations cause morphogenetic defects and apoptotic cell death in Drosophila melanogaster , 1996, Molecular and cellular biology.
[44] M. Taylor,et al. Protective immunity against Onchocerca volvulus and O. lienalis infective larvae in mice. , 1994, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.
[45] R. Lucius,et al. The filarial antigens Av33/Ov33-3 show striking similarities to the major pepsin inhibitor from Ascaris suum. , 1993, Molecular and biochemical parasitology.
[46] G. Bloom. Motor proteins for cytoplasmic microtubules , 1992, Current Biology.
[47] K. Fujikawa,et al. Primary structure of the major pepsin inhibitor from the intestinal parasitic nematode Ascaris suum. , 1990, Biochemistry.
[48] J. Donelson,et al. OvGalBP, a filarial antigen with homology to vertebrate galactoside-binding proteins. , 1994, Molecular and biochemical parasitology.
[49] A. Scott,et al. Molecular cloning of a serine proteinase inhibitor from Brugia malayi , 1995, Infection and immunity.
[50] J. Barry,et al. Temporal reiteration of a precise gene expression pattern during nematode development. , 1996, The EMBO journal.
[51] R. Laskey,et al. Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence , 1991, Cell.
[52] W. F. Gregory,et al. Age‐specific acquisition of immunity to infective larvae in a bancroftian filariasis endemic area of Papua New Guinea , 1991, Parasite immunology.
[53] J. Daub,et al. A survey of genes expressed in adults of the human hookworm, Necator americanus , 2000, Parasitology.
[54] R. Jenkins,et al. Protective immunity induced by vaccination with Onchocerca volvulus tropomyosin in rodents , 1996, Parasite immunology.
[55] K. F. Tabbarra. Onchocerciasis and its Control , 1996 .
[56] M. Taylor,et al. Characterization of a secreted antigen of Onchocerca volvulus with host‐protective potential , 1996, Parasite immunology.
[57] J. McCarthy,et al. A Cyclosporin A-sensitive small molecular weight cyclophilin of filarial parasites. , 1996, Molecular and biochemical parasitology.
[58] K. Mehta,et al. Transglutaminase-catalyzed reaction is important for molting of Onchocerca volvulus third-stage larvae , 1995, Antimicrobial agents and chemotherapy.
[59] J. E. Rall,et al. Steroid/thyroid hormone receptor genes in Caenorhabditis elegans. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[60] A. Winter,et al. A divergent multi-domain cyclophilin is highly conserved between parasitic and free-living nematode species and is important in larval muscle development. , 1998, Molecular and biochemical parasitology.
[61] D. Vassilatis,et al. Cloning of an avermectin-sensitive glutamate-gated chloride channel from Caenorhabditis elegans , 1994, Nature.
[62] H. Gamble,et al. Purification of a 44 kilodalton protease which mediates the ecdysis of infective Haemonchus contortus larvae. , 1989, Molecular and biochemical parasitology.
[63] R. Maizels,et al. Identification of Abundantly Expressed Novel and Conserved Genes from the Infective Larval Stage of Toxocara canis by an Expressed Sequence Tag Strategy , 1999, Infection and Immunity.
[64] R. Bucala,et al. Filarial Nematode Parasites Secrete a Homologue of the Human Cytokine Macrophage Migration Inhibitory Factor , 1998, Infection and Immunity.
[65] T. Nutman,et al. Immunity to onchocerciasis: identification of a putatively immune population in a hyperendemic area of Ecuador. , 1994, The Journal of infectious diseases.
[66] J. Berg. Genome sequence of the nematode C. elegans: a platform for investigating biology. , 1998, Science.
[67] R. W. Padgett,et al. Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[68] M. Blaxter,et al. Differentially expressed, abundant trans-spliced cDNAs from larval Brugia malayi. , 1997, Molecular and biochemical parasitology.
[69] G. Wilson,et al. Molecular characterization of a cyclosporin A-insensitive cyclophilin from the parasitic nematode Brugia malayi. , 1995, Biochemistry.
[70] M. Taylor,et al. Onchocerca volvulus larval antigen, OvB20, induces partial protection in a rodent model of onchocerciasis , 1995, Infection and immunity.
[71] Thomas L. Madden,et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.
[72] G. Frank,et al. Molecular cloning of a developmentally regulated protein isolated from excretory-secretory products of larval Dirofilaria immitis. , 1996, Molecular and biochemical parasitology.
[73] V. Fried,et al. A hookworm glycoprotein that inhibits neutrophil function is a ligand of the integrin CD11b/CD18. , 1994, The Journal of biological chemistry.
[74] N. Sangster,et al. Pharmacology of anthelmintic resistance. , 1999, Parasitology today.
[75] J. Browne,et al. Onchocerca volvulus: a comparative study of in vitro neutrophil killing of microfilariae and humoral responses in infected and endemic normals. , 1995, Experimental parasitology.
[76] J. Browne,et al. Onchocerca volvulus: in vitro cytotoxic effects of human neutrophils and serum on third-stage larvae. , 1994, Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit.
[77] J. McKerrow,et al. Cloning of a Cysteine Protease Required for the Molting of Onchocerca volvulus Third Stage Larvae* , 1996, The Journal of Biological Chemistry.
[78] S. Lustigman,et al. Identification of larval-stage-specific antigens of Onchocerca volvulus uniquely recognized by putative immune sera from humans and vaccination sera from animal models. , 1997, Annals of tropical medicine and parasitology.
[79] W. F. Gregory,et al. Onchocerca volvulus: characterization of an immunodominant hypodermal antigen present in adult and larval parasites. , 1993, Experimental parasitology.
[80] N. Raikhel,et al. Protein import into the nucleus: an integrated view. , 1995, Annual review of cell and developmental biology.
[81] R. Tuan,et al. Characterization of genes encoding members of the nuclear hormone receptor superfamily from Onchocerca volvulus. , 1995, Molecular and biochemical parasitology.
[82] M. Blaxter,et al. Genes expressed in Brugia malayi infective third stage larvae. , 1996, Molecular and biochemical parasitology.
[83] M. Taylor,et al. Tropomyosin implicated in host protective responses to microfilariae in onchocerciasis. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[84] R. Maizels,et al. A novel serpin expressed by blood-borne microfilariae of the parasitic nematode Brugia malayi inhibits human neutrophil serine proteinases. , 1999, Blood.
[85] P. Hotez,et al. Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum. , 1999, Molecular and biochemical parasitology.