Multiple Forms of Rabbit Cytochrome P450: Comparison of Chemical Physical, Immunological and Biocatalytic Properties
暂无分享,去创建一个
[1] B. Masters,et al. Cloning and expression of three rabbit kidney cDNAs encoding lauric acid omega-hydroxylases. , 1990, Biochemistry.
[2] T. Kronbach,et al. Hybrid cytochromes P-450 identify a substrate binding domain in P-450IIC5 and P-450IIC4. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[3] T. Poulos,et al. Putidaredoxin competitively inhibits cytochrome b5-cytochrome P-450cam association: a proposed molecular model for a cytochrome P-450cam electron-transfer complex. , 1989, Biochemistry.
[4] P. Beaune,et al. The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction. , 1989, British journal of clinical pharmacology.
[5] R. Tukey,et al. Regulation of the rabbit cytochrome P-450 3c gene. Age-dependent expression and transcriptional activation by rifampicin. , 1989, The Journal of biological chemistry.
[6] S. Imaoka,et al. Purification and characterization of hepatic microsomal prostaglandin omega-hydroxylase cytochrome P-450 from pregnant rabbits. , 1989, Journal of biochemistry.
[7] R. Tukey,et al. Genetic contributions to the variation among rabbits of liver microsomal deoxycorticosterone synthesis. , 1989, Archives of biochemistry and biophysics.
[8] J. Falck,et al. Metabolism of 20-hydroxyeicosatetraenoic acid by cyclooxygenase. Formation and identification of novel endothelium-dependent vasoconstrictor metabolites. , 1989, The Journal of biological chemistry.
[9] M. J. Coon,et al. Induction and tissue-specific expression of rabbit cytochrome P450IIE1 and IIE2 genes. , 1989, Molecular pharmacology.
[10] T. Poulos. Reversing enzyme specificity , 1989, Nature.
[11] R. Lindberg,et al. Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue , 1989, Nature.
[12] P. Srivastava,et al. Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae. , 1989, Biochemistry.
[13] G. Vergères,et al. Identification of the membrane anchor of microsomal rat liver cytochrome P-450. , 1989, Biochemistry.
[14] R J Edwards,et al. Identification and location of alpha-helices in mammalian cytochromes P450. , 1989, Biochemistry.
[15] R. Gasser,et al. Primary structures of cytochrome P-450 isozyme 5 from rabbit and rat and regulation of species-dependent expression and induction in lung and liver: identification of cytochrome P-450 gene subfamily IVB. , 1989, Molecular pharmacology.
[16] Y. Nogi,et al. Expression of a human P-450IIC gene in yeast cells using galactose-inducible expression system. , 1989, Molecular pharmacology.
[17] S. D. Black,et al. Membrane topology of mammalian cytochromes P-450 from liver endoplasmic reticulum. Determination by trypsinolysis of phenobarbital-treated microsomes. , 1989, The Journal of biological chemistry.
[18] J. Derancourt,et al. Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily. , 1989, Drug metabolism and disposition: the biological fate of chemicals.
[19] D. Nelson,et al. Secondary structure prediction of 52 membrane-bound cytochromes P450 shows a strong structural similarity to P450cam. , 1989, Biochemistry.
[20] S. Sligar,et al. The roles of active site hydrogen bonding in cytochrome P-450cam as revealed by site-directed mutagenesis. , 1988, The Journal of biological chemistry.
[21] E. Johnson,et al. Positive effectors of the binding of an active site-directed amino steroid to rabbit cytochrome P-450 3c. , 1988, The Journal of biological chemistry.
[22] P. Srivastava,et al. Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase. , 1988, Biochemistry.
[23] G. Kreibich,et al. Signals for the incorporation and orientation of cytochrome P450 in the endoplasmic reticulum membrane , 1988, The Journal of cell biology.
[24] E. Johnson,et al. Modulation of rabbit and human hepatic cytochrome P-450-catalyzed steroid hydroxylations by alpha-naphthoflavone. , 1988, Molecular pharmacology.
[25] D. Mead,et al. Positive charges at the NH2 terminus convert the membrane-anchor signal peptide of cytochrome P-450 to a secretory signal peptide. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[26] S. Tsunasawa,et al. Microheterogeneity in the major phenobarbital-inducible forms of rabbit liver microsomal cytochrome P-450 as revealed by nucleotide sequencing of cloned cDNAs. , 1988, Biochemistry.
[27] D. Williams,et al. Regulation of the induction of a cytochrome P-450 prostaglandin omega-hydroxylase by pregnancy in rabbit lung. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[28] O. Gotoh,et al. cDNA cloning and inducible expression during pregnancy of the mRNA for rabbit pulmonary prostaglandin omega-hydroxylase (cytochrome P-450p-2). , 1987, The Journal of biological chemistry.
[29] T. Poulos,et al. High-resolution crystal structure of cytochrome P450cam. , 1987, Journal of molecular biology.
[30] N. Kagawa,et al. Structural analysis of cloned cDNAs for polycyclic hydrocarbon-inducible forms of rabbit liver microsomal cytochrome P-450. , 1987, Journal of biochemistry.
[31] R. Tukey,et al. Characterization of a second gene product related to rabbit cytochrome P-450 1. , 1987, The Journal of biological chemistry.
[32] M. J. Coon,et al. cDNA and derived amino acid sequence of ethanol-inducible rabbit liver cytochrome P-450 isozyme 3a (P-450ALC). , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[33] F. Gonzalez,et al. Isolation, complementary DNA sequence, and regulation of rat hepatic lauric acid omega-hydroxylase (cytochrome P-450LA omega). Identification of a new cytochrome P-450 gene family. , 1987, The Journal of biological chemistry.
[34] C. Kasper,et al. Induction of the hepatic mixed-function oxidase system by synthetic glucocorticoids. Transcriptional and post-transcriptional regulation. , 1987, The Journal of biological chemistry.
[35] F. Gonzalez,et al. Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme. , 1986, The Journal of biological chemistry.
[36] B. Kemper,et al. Evidence that rabbit cytochrome P-450 K is encoded by the plasmid pP-450 PBc2. , 1986, Biochemical and biophysical research communications.
[37] S. Govind,et al. Structure of genes in the cytochrome P-450PBc subfamily: conservation of intron locations in the phenobarbital-inducible family. , 1986, DNA.
[38] S. Yamamoto,et al. Effect of peroxisomal proliferators on microsomal prostaglandin A omega-hydroxylase. , 1986, Journal of biochemistry.
[39] J. Blanchard,et al. Cloning of a cDNA coding for P-450 LM3c from rabbit liver microsomes and regulation of its expression. , 1986, Nucleic acids research.
[40] P. Watkins,et al. Macrolide antibiotics inhibit the degradation of the glucocorticoid-responsive cytochrome P-450p in rat hepatocytes in vivo and in primary monolayer culture. , 1986, The Journal of biological chemistry.
[41] J. Ozols. Complete amino acid sequence of a cytochrome P-450 isolated from beta-naphthoflavone-induced rabbit liver microsomes. Comparison with phenobarbital-induced and constitutive isozymes and identification of invariant residues. , 1986, The Journal of biological chemistry.
[42] S. Sligar,et al. Nucleotide sequence of the Pseudomonas putida cytochrome P-450cam gene and its expression in Escherichia coli. , 1986, The Journal of biological chemistry.
[43] G. Schwab,et al. Two catalytically distinct subforms of cytochrome P-450 3b as obtained from inbred rabbits. , 1985, Biochemistry.
[44] R. Tukey,et al. Multiple gene-like sequences related to the rabbit hepatic progesterone 21-hydroxylase cytochrome P-450 1. , 1985, The Journal of biological chemistry.
[45] O. Hayaishi. Advances in Prostaglandin, Thromboxane, and Leukotriene Research , 1985 .
[46] P. Watkins,et al. Demonstration in multiple species of inducible hepatic cytochromes P-450 and their mRNAs related to the glucocorticoid-inducible cytochrome P-450 of the rat. , 1985, Molecular pharmacology.
[47] P. Watkins,et al. Identification of an inducible form of cytochrome P-450 in human liver. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[48] R. Tukey,et al. Cloning and characterization of cDNAs encoding 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible rabbit mRNAs for cytochrome P-450 isozymes 4 and 6. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[49] G. Maurer. Metabolism of cyclosporine. , 1985, Transplantation proceedings.
[50] L. Ghizzoni,et al. Characterization of variations in rabbit hepatic progesterone 21-hydroxylase activity by serial biopsy. , 1985, Biochemical and biophysical research communications.
[51] I. Phillips,et al. Induction of cytochrome P-450 by phenobarbital is mediated at the level of transcription. , 1985, Biochemical pharmacology.
[52] J. Ozols,et al. The complete amino acid sequence of a constitutive form of liver microsomal cytochrome P-450. , 1985, The Journal of biological chemistry.
[53] K. Griffin,et al. Variations in hepatic progesterone 21-hydroxylase activity reflect differences in the microsomal concentration of rabbit cytochrome P-450 1. , 1985, Archives of biochemistry and biophysics.
[54] G. Schwab,et al. Variation in hepatic microsomal cytochrome P-450 1 concentration among untreated rabbits alters the efficiency of estradiol hydroxylation. , 1985, Archives of biochemistry and biophysics.
[55] J. Raucy,et al. Variations among untreated rabbits in benzo(a)pyrene metabolism and its modulation by 7,8-benzoflavone. , 1985, Molecular pharmacology.
[56] C. Larroque,et al. Isolation and partial characterization of a rifampicin induced rabbit liver microsomal cytochrome P-450. , 1985, Biochemical and biophysical research communications.
[57] D. Williams,et al. A prostaglandin omega-hydroxylase cytochrome P-450 (P-450PG-omega) purified from lungs of pregnant rabbits. , 1984, The Journal of biological chemistry.
[58] M. J. Coon,et al. Immunochemical evidence for a role of cytochrome P-450 in liver microsomal ethanol oxidation. , 1984, Archives of biochemistry and biophysics.
[59] M. Ingelman-Sundberg,et al. Induction of the ethanol-inducible form of rabbit liver microsomal cytochrome P-450 by inhibitors of alcohol dehydrogenase. , 1984, Biochemical and biophysical research communications.
[60] K. Griffin,et al. Use of a monoclonal antibody specific for rabbit microsomal cytochrome P-450 3b to characterize the participation of this cytochrome in the microsomal 6 beta- and 16 alpha-hydroxylation of progesterone. , 1984, Biochemistry.
[61] B. Kemper,et al. Differential induction and tissue-specific expression of closely related members of the phenobarbital-inducible rabbit cytochrome P-450 gene family. , 1984, The Journal of biological chemistry.
[62] R. Tukey,et al. Structural gene products of the Ah locus. Transcriptional regulation of cytochrome P1-450 and P3-450 mRNA levels by 3-methylcholanthrene. , 1984, Molecular pharmacology.
[63] K. Griffin,et al. Three monoclonal antibodies to rabbit microsomal cytochrome P-450 1 recognize distinct epitopes that are shared to different degrees among other electrophoretic types of cytochrome P-450. , 1984, The Journal of biological chemistry.
[64] J. Whitlock,et al. Regulation of cytochrome P1-450 gene transcription by 2,3,7, 8-tetrachlorodibenzo-p-dioxin in wild type and variant mouse hepatoma cells. , 1984, The Journal of biological chemistry.
[65] B. Kemper,et al. Isolation and sequence analysis of three cloned cDNAs for rabbit liver proteins that are related to rabbit cytochrome P-450 (form 2), the major phenobarbital-inducible form. , 1984, Biochemistry.
[66] M. J. Coon,et al. Complete amino acid sequence and predicted membrane topology of phenobarbital-induced cytochrome P-450 (isozyme 2) from rabbit liver microsomes. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[67] C. Kasper,et al. Transcriptional regulation of rat liver epoxide hydratase, NADPH-Cytochrome P-450 oxidoreductase, and cytochrome P-450b genes by phenobarbital. , 1983, The Journal of biological chemistry.
[68] I. Senciall,et al. Progesterone C21 hydroxylation and steroid carboxylic acid biosynthesis in the rabbit. In vitro studies with endocrine, metabolic, and potential target tissues. , 1983, Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire.
[69] J. Ozols,et al. The complete amino acid sequence of rabbit phenobarbital-induced liver microsomal cytochrome P-450. , 1983, The Journal of biological chemistry.
[70] E. Johnson,et al. Allosteric regulation of the 16 alpha-hydroxylation of progesterone as catalyzed by rabbit microsomal cytochrome P-450 3b. , 1983, The Journal of biological chemistry.
[71] M. Ingelman-Sundberg,et al. On the significance of the cytochrome P-450-dependent hydroxyl radical-mediated oxygenation mechanism. , 1982, Xenobiotica; the fate of foreign compounds in biological systems.
[72] H. H. Dieter,et al. Functional and structural polymorphism of rabbit microsomal cytochrome P-450 form 3b. , 1982, The Journal of biological chemistry.
[73] U. Muller-eberhard,et al. Rabbit hepatic progesterone 21-hydroxylase exhibits a bimodal distribution of activity. , 1982, Science.
[74] M. J. Coon,et al. Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits. , 1982, The Journal of biological chemistry.
[75] U. Muller-eberhard,et al. Identification of rabbit microsomal cytochrome P-450 isozyme, form 1, as a hepatic progesterone 21-hydroxylase. , 1982, Biochemical and biophysical research communications.
[76] M. J. Coon,et al. Specificity in the activation and inhibition by flavonoids of benzo[a]pyrene hydroxylation by cytochrome P-450 isozymes from rabbit liver microsomes. , 1981, The Journal of biological chemistry.
[77] M. J. Coon,et al. Properties of electrophoretically homogeneous constitutive forms of liver microsomal cytochrome P-450. , 1981, The Journal of biological chemistry.
[78] K. Ogita,et al. Effect of Cytochrome b5 on Fatty Acid ω- and (ω-1)-Hydroxylation Catalyzed by Partially Purified Cytochrome P-450 from Rabbit Kidney Cortex Microsomes , 1981 .
[79] M. Huang,et al. Studies on the mechanism of activation of microsomal benzo[a]pyrene hydroxylation by flavonoids. , 1981, The Journal of biological chemistry.
[80] D. Jerina,et al. Species-specific enhancement by 7,8-benzoflavone of hepatic microsomal metabolism of benzo[e]pyrene 9,10-dihydrodiol to bay-region diol epoxides. , 1981, Cancer research.
[81] U. Muller-eberhard,et al. Identification of the form of cytochrome P-450 induced in neonatal rabbit liver microsomes by phenobarbital. , 1980, Molecular pharmacology.
[82] E. Johnson,et al. Isolation and characterization of a constitutive form of rabbit liver microsomal cytochrome P-450. , 1980, The Journal of biological chemistry.
[83] M. J. Coon,et al. Purification and properties of P-450LM3b, a constitutive form of cytochrome P-450, from rabbit liver microsomes. , 1979, Biochemical and biophysical research communications.
[84] P. Thomas,et al. Preparation of monospecific antibodies against two forms of rat liver cytochrome P-450 and quantitation of these antigens in microsomes. , 1979, Archives of biochemistry and biophysics.
[85] U. Muller-eberhard,et al. Identification of the major cytochrome P-450 form transplacentally induced in neonatal rabbits by 3,3,7,8-tetrachlorodibenzo-p-dioxin. , 1978, Journal of Biological Chemistry.
[86] W. Powell. omega-Oxidation of prostaglandins by lung and liver microsomes. Changes in enzyme activity induced by pregnancy, pseudopregnancy, and progesterone treatment. , 1978, The Journal of biological chemistry.
[87] A. Kappas,et al. 7,8-Benzoflavone stimulates the metabolic activation of aflatoxin B1 to mutagens by human liver. , 1978, Biochemical and biophysical research communications.
[88] A. Conney,et al. Activation of monooxygenases in human liver by 7,8‐benzoflavone , 1977, Clinical pharmacology and therapeutics.
[89] M. J. Coon,et al. Amino-terminal sequence of phenobarbital-inducible cytochrome P-450 from rabbit liver microsomes: similarity to hydrophobic amino-terminal segments of preproteins. , 1977, Biochemical and biophysical research communications.
[90] U. Muller-eberhard,et al. Purification of the major cytochrome P-450 of liver microsomes from rabbits treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). , 1977, Biochemical and biophysical research communications.
[91] U. Muller-eberhard,et al. Multiple forms of cytochrome P-450: resolution and purification of rabbit liver aryl hydrocarbon hydroxylase. , 1977, Biochemical and biophysical research communications.
[92] M. J. Coon,et al. Properties of electrophoretically homogeneous phenobarbital-inducible and beta-naphthoflavone-inducible forms of liver microsomal cytochrome P-450. , 1976, The Journal of biological chemistry.
[93] R. Philpot,et al. Separation and purification of two forms of hepatic cytochrome P-450 from untreated rabbits. , 1976, Molecular pharmacology.
[94] Y. Imai,et al. Purification of a substrate complex of cytochrome P-450 from liver microsomes of 3-methylcholanthrene-treated rabbits. , 1976, Biochemical and biophysical research communications.
[95] A. Y. Lu,et al. Purification of liver microsomal cytochrome P-448 from 3-methylcholanthrene-treated rabbits. , 1975, Molecular pharmacology.
[96] M. J. Coon,et al. Purified liver microsomal cytochrome P-450. Separation and characterization of multiple forms. , 1975, The Journal of biological chemistry.
[97] M. J. Coon,et al. Cytochrome P-450 purified to apparent homogeneity from phenobarbital-induced rabbit liver microsomes: catalytic activity and other properties. , 1974, Biochemical and biophysical research communications.
[98] Y. Imai,et al. A gel-electrophoretically homogeneous preparation of cytochrome P-450 from liver microsomes of phenobarbital-pretreated rabbits. , 1974, Biochemical and biophysical research communications.
[99] M. J. Coon,et al. Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components. , 1969, The Journal of biological chemistry.
[100] R. Branch,et al. Genetic polymorphism of S-mephenytoin hydroxylation. , 1989, Pharmacology & therapeutics.
[101] M. J. Coon,et al. The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci. , 1989, DNA.
[102] Y. Imai. Characterization of rabbit liver cytochrome P-450 (laurate omega-1 hydroxylase) synthesized in transformed yeast cells. , 1988, Journal of biochemistry.
[103] P. Fort,et al. Complete sequence of cytochrome P450 3c cDNA and presence of two mRNA species with 3' untranslated regions of different lengths. , 1988, DNA.
[104] M. Negishi,et al. Primary structures of multiple forms of cytochrome P-450 isozyme 2 derived from rabbit pulmonary and hepatic cDNAs. , 1988, Molecular pharmacology.
[105] J. Dees,et al. Differential expression of cytochrome P-450 1 and related forms in rabbit liver and kidney. , 1987, Archives of biochemistry and biophysics.
[106] M. J. Coon,et al. Cytochrome P-450 isozymes 2 and 5 in rabbit lung and liver. Comparisons of structure and inducibility. , 1987, Drug metabolism and disposition: the biological fate of chemicals.
[107] 香川 憲夫. Molecular cloning and structural analysis of cDNAs encoding polycyclic hydrocarbon-inducible forms of rabbit liver microsomal cytochrome P-450 , 1986 .
[108] S. Yamamoto,et al. Isolation of cytochrome P-450 highly active in prostaglandin omega-hydroxylation from lung microsomes of rabbits treated with progesterone. , 1984, Journal of biochemistry.
[109] A. Conney,et al. Activation and inhibition of benzo(a)pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occurring flavonoids. , 1981, Cancer research.
[110] D. Kupfer. Endogenous substrates of monooxygenases: fatty acids and prostaglandins. , 1980, Pharmacology & therapeutics.
[111] U. Muller-eberhard,et al. Characterization of three forms of rabbit microsomal cytochrome P-450 by peptide mapping utilizing limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. , 1979, Archives of biochemistry and biophysics.