AF64A depletes hippocampal high-affinity choline uptake but does not alter the density of α-bungarotoxin binding sites or modify the effect of exogenous choline

[1]  B. Morley,et al.  AF64 depletes hypothalamic high-affinity choline uptake and disrupts the circadian rhythm of locomotor activity without altering the density of nicotinic acetylcholine receptors , 1989, Brain Research.

[2]  P. Potter,et al.  Inhibition of high affinity choline transport attenuates both cholinergic and non-cholinergic effects of ethylcholine aziridinium (AF64A) , 1989, Brain Research.

[3]  B. Morley.  Alpha-bungarotoxin receptors in the CNS. , 1989, Progress in brain research.

[4]  C. Estrada,et al.  Biochemical and histological modifications of the rat retina induced by the cholinergic neurotoxin AF64A , 1988, Brain Research.

[5]  W. D. Blaker,et al.  Biochemical and behavioral effects of intrahippocampal AF64A in rats , 1987, Pharmacology Biochemistry and Behavior.

[6]  B. Morley,et al.  A time course and dose-response study of the regulation of brain nicotinic receptors by dietary choline , 1987, Brain Research.

[7]  A. Fisher,et al.  Reversible and Irreversible Inhibition of High‐Affinity Choline Transport Caused by Ethylcholine Aziridinium Ion , 1987, Journal of neurochemistry.

[8]  P. Potter,et al.  Effect of cholinergic deficit induced by ethylcholine aziridinium on serotonergic parameters in rat brain , 1987, Neuroscience.

[9]  L. Butcher,et al.  Is ethylcholine mustard aziridinium ion a specific cholinergic neurotoxin? , 1987, Neuroscience.

[10]  T. J. Walsh,et al.  AF64A (ethylcholine aziridinium ion), a cholinergic neurotoxin, selectively impairs working memory in a multiple component T-maze task , 1987, Brain Research.

[11]  T. Millar,et al.  The toxic effects of ethylcholine mustard aziridinium ion on cholinergic cells in the chicken retina , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[12]  E. Vizi,et al.  Selective impairment of acetylcholine release and content in the central nervous system following intracerebroventricular administration of ethylcholine mustard aziridinium ion (AF64A) in the rat , 1986, Neurochemistry International.

[13]  R J Rylett,et al.  An Attempt to Produce Cholinergic Hypofunction in Rat Brain using Choline Mustard Aziridinium Ion: Neurochemical and Histological Parameters , 1986, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[14]  F. Fonnum,et al.  Ultrastructural and neurochemical effects of the presumed cholinergic toxin AF64A in the rat interpeduncular nucleus , 1986, Brain Research.

[15]  B. Morley,et al.  Increases in the concentration of brain α-bungarotoxin binding sites induced by dietary choline are age-dependent , 1986, Brain Research.

[16]  D. Davies,et al.  Cholinergic neurotoxicity induced by ethylcholine aziridinium (AF64A) in neuron-enriched cultures , 1986, Brain Research.

[17]  A. Fisher,et al.  Histochemical and Electronmicroscopic Study of the Brain of the AF64A-Treated Rat , 1986 .

[18]  H. Yamamura,et al.  Regional differences in ethylcholine mustard aziridinium ion (AF64A)-induced deficits in presynaptic cholinergic markers for the rat central nervous system. , 1985, The Journal of pharmacology and experimental therapeutics.

[19]  M. McNamee,et al.  Purification and characterization of the α-bungarotoxin binding protein from rat brain , 1985, Brain Research.

[20]  E. Barnard,et al.  Brain and muscle nicotinic acetylcholine receptors are different but homologous proteins. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[21]  J. Coyle,et al.  Method for the quantitation and characterization of the cholinergic neurotoxin, monoethylcholine mustard aziridinium ion (AF64A) , 1985, Journal of Neuroscience Methods.

[22]  D. McKeag,et al.  Intracerebroventricular administration of ethylcholine mustard aziridinium ion (AF64A) reduces release of acetylcholine from rat hippocampal slices , 1985, Neuropharmacology.

[23]  T. J. Walsh,et al.  AF64A, a cholinergic neurotoxin, selectively depletes acetylcholine in hippocampus and cortex, and produces long-term passive avoidance and radial-arm maze deficits in the rat , 1984, Brain Research.

[24]  L. Jarrard,et al.  Non-cholinergic neurotoxic effects of AF64A in the substantia nigra , 1984, Brain Research.

[25]  J. Coyle,et al.  Selective cholinergic neurotoxin: AF64A's effects in rat striatum , 1984, Brain Research.

[26]  E. Mimnaugh,et al.  Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers. , 1983, The Journal of pharmacology and experimental therapeutics.

[27]  M. Zigmond,et al.  Selective Presynaptic Cholinergic Neurotoxicity Following Intrahippocampal AF64A Injection in Rats , 1983, Journal of neurochemistry.

[28]  G. Kemp,et al.  Characterization of a putative nicotinic acetylcholine receptor in mammalian brain , 1981, Brain Research Reviews.

[29]  A. Fisher,et al.  The AF64a-treated mouse: possible model for central cholinergic hypofunction. , 1981, Science.

[30]  B. Morley.  The properties of brain nicotine receptors. , 1981, Pharmacology & therapeutics.

[31]  Y. Arimatsu,et al.  Localization of α-bungarotoxin binding sites in mouse brain by light and electron microscopic autoradiography , 1978, Brain Research.

[32]  S. Hunt,et al.  The electron microscopic autoradiographic localization of α-bungarotoxin binding sites within the central nervous system of the rat , 1978, Brain Research.

[33]  R. Bradley,et al.  Regional distribution of nicotinic acetylcholine receptor in rat brain , 1977, Brain Research.

[34]  R. Bradley,et al.  Effects of dietary choline on nicotinic acetylcholine receptors in brain , 1977, Nature.

[35]  M. Kuhar,et al.  Activation of high-affinity choline uptake in vitro by depolarizing agents. , 1976, Molecular pharmacology.

[36]  O. H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.