Concurrent oral shedding of feline calicivirus and feline herpesvirus 1 in cats with chronic gingivostomatitis.

Oral mucosal salivary samples were collected from 25 cats with chronic gingivostomatitis and 24 cats with periodontal disease. Viral culture and isolation of feline calicivirus and feline herpesvirus 1 were performed. Eighty-eight per cent of cats with chronic gingivostomatitis were shedding both viruses, compared to 21% of cats without chronic oral inflammatory disease. Cats with chronic gingivostomatitis are significantly more likely to concurrently shed both feline calicivirus and feline herpesvirus 1 than are cats with classical periodontal disease.

[1]  J. Slots,et al.  Herpesviruses: a unifying causative factor in periodontitis? , 2000, Oral microbiology and immunology.

[2]  R. Johnson,et al.  Sites of persistence of feline calicivirus. , 1989, Research in veterinary science.

[3]  J. Taboada,et al.  Systemic diseases with cutaneous manifestations. , 1995, The Veterinary clinics of North America. Small animal practice.

[4]  D. Greenspan,et al.  Herpetic gingivostomatitis in a 70-year-old man. , 1995, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[5]  T. J. Gruffydd-Jones,et al.  Cytokine mRNA Expression in Lesions in Cats with Chronic Gingivostomatitis , 1999, Clinical Diagnostic Laboratory Immunology.

[6]  Scott Fw,et al.  Long-term immunity in cats vaccinated with an inactivated trivalent vaccine. , 1999, American journal of veterinary research.

[7]  J. Slots,et al.  Herpesviruses in human periodontal disease. , 2000, Journal of periodontal research.

[8]  A M Hargis,et al.  Feline herpesvirus 1-associated facial and nasal dermatitis and stomatitis in domestic cats. , 1999, The Veterinary clinics of North America. Small animal practice.

[9]  U. Truyen,et al.  Genetic and antigenic heterogeneity among feline calicivirus isolates from distinct disease manifestations. , 1997, Virus research.

[10]  C. Greene,et al.  Comparison of nested polymerase chain reaction, virus isolation, and fluorescent antibody testing for identifying feline herpesvirus in cats with conjunctivitis. , 1997, American journal of veterinary research.

[11]  H. Kida,et al.  Detection of feline herpesvirus 1 transcripts in trigeminal ganglia of latently infected cats , 2005, Archives of Virology.

[12]  K. Gulliya,et al.  Effects of Preactivated MC540 in the Treatment of Lymphocytic Plasmacytic Stomatitis in Feline Leukemia virus and Feline Immunodeficiency virus Positive Cats , 1993, Journal of veterinary dentistry.

[13]  J. Regezi,et al.  Vascular adhesion molecules in oral lichen planus. , 1996, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[14]  B. Seal,et al.  Phenotypic and genotypic variation of feline calicivirus during persistent infection of cats. , 1998, Veterinary microbiology.

[15]  D. Harbour,et al.  Chronic gingivitis in a colony of cats infected with feline immunodeficiency virus and feline calicivirus , 1993, Veterinary Record.

[16]  R. Rosychuk,et al.  Feline gingivitis-stomatitis-pharyngitis. , 1993, The Veterinary clinics of North America. Small animal practice.

[17]  R. Wardley,et al.  The pathology and sites of persistence associated with three different strains of feline calicivirus. , 1977, Research in veterinary science.

[18]  N. Pedersen,et al.  Inflammatory Oral Cavity Diseases of the Cat , 1992, Veterinary Clinics of North America: Small Animal Practice.

[19]  D. Chisholm,et al.  Plasma cell mucositis: a review and case report. , 2007, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[20]  S. Dawson,et al.  Neutralisation patterns among recent British and North American feline calicivirus isolates from different clinical origins , 1990, Veterinary Record.

[21]  G. Reubel,et al.  Acute and chronic faucitis of domestic cats. A feline calicivirus-induced disease. , 1992, The Veterinary clinics of North America. Small animal practice.

[22]  G. Browning,et al.  Detection of feline calicivirus, feline herpesvirus 1 and Chlamydia psittaci mucosal swabs by multiplex RT-PCR/PCR. , 2001, Veterinary microbiology.

[23]  M. Siegel,et al.  Diagnosing and treating common oral pathologies. , 1991, Pediatric clinics of North America.

[24]  O. Jarrett,et al.  Serological analysis of feline calicivirus isolates from the United States and United Kingdom. , 1997, Veterinary microbiology.

[25]  H. Poulet,et al.  Comparison between acute oral/respiratory and chronic stomatitis/gingivitis isolates of feline calicivirus: pathogenicity, antigenic profile and cross-neutralisation studies , 2000, Archives of Virology.

[26]  G. Reubel,et al.  Effect of chronic feline immunodeficiency virus infection on experimental feline calicivirus-induced disease. , 1994, Veterinary microbiology.

[27]  G. Browning,et al.  Differential sensitivity of culture and the polymerase chain reaction for detection of feline herpesvirus 1 in vaccinated and unvaccinated cats , 1997, Archives of Virology.

[28]  G. Wilcox,et al.  Association of calicivirus infection with chronic gingivitis and pharyngitis in cats , 1984 .

[29]  H Lutz,et al.  Prevalence of feline calicivirus, feline leukaemia virus and antibodies to FIV in cats with chronic stomatitis , 1989, Veterinary Record.

[30]  N. Pedersen,et al.  Chronic oral infections of cats and their relationship to persistent oral carriage of feline calici-, immunodeficiency, or leukemia viruses. , 1991, Veterinary immunology and immunopathology.

[31]  N. Christou,et al.  Endothelial Cells: Role in Infection and Inflammation , 1998, World Journal of Surgery.

[32]  L. R. Eversole,et al.  Immunopathogenesis of oral lichen planus and recurrent aphthous stomatitis. , 1997, Seminars in cutaneous medicine and surgery.

[33]  B. Sherry,et al.  High sensitivity polymerase chain reaction assay for active and latent feline herpesvirus- infections in domestic cats , 1997, Veterinary Record.

[34]  G. Reubel,et al.  Detection of active and latent feline herpesvirus 1 infections using the polymerase chain reaction , 2005, Archives of Virology.

[35]  S. Dawson,et al.  Typing of feline calicivirus isolates from different clinical groups by virus neutralisation tests , 1993, Veterinary Record.