Production of the soluble form of KIT, s-KIT, abolishes stem cell factor-induced melanogenesis in human melanocytes.
暂无分享,去创建一个
[1] D. Kardassis,et al. Exposure of normal human melanocytes to a tumor promoting phorbol ester reverses growth suppression by transforming growth factor beta , 2008, Journal of cellular physiology.
[2] L. Larue,et al. Notch1 and Notch2 receptors influence progressive hair graying in a dose‐dependent manner , 2007, Developmental dynamics : an official publication of the American Association of Anatomists.
[3] S. Nishikawa,et al. Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells , 2006, The Journal of cell biology.
[4] Johan Lennartsson,et al. Normal and Oncogenic Forms of the Receptor Tyrosine Kinase Kit , 2005, Stem cells.
[5] A. Hachiya,et al. Biphasic expression of two paracrine melanogenic cytokines, stem cell factor and endothelin-1, in ultraviolet B-induced human melanogenesis. , 2004, The American journal of pathology.
[6] L. Rönnstrand. Signal transduction via the stem cell factor receptor/c-Kit , 2004, Cellular and Molecular Life Sciences CMLS.
[7] Kyoung-Chan Park,et al. Transforming growth factor-beta1 decreases melanin synthesis via delayed extracellular signal-regulated kinase activation. , 2004, The international journal of biochemistry & cell biology.
[8] G. Imokawa,et al. The epidermal stem cell factor is over-expressed in lentigo senilis: implication for the mechanism of hyperpigmentation. , 2004, The Journal of investigative dermatology.
[9] M. Kawaguchi,et al. Localization of tumour necrosis factor‐α converting enzyme in normal human skin , 2004 .
[10] J. Peschon,et al. Tumor Necrosis Factor-α-converting Enzyme Controls Surface Expression of c-Kit and Survival of Embryonic Stem Cell-derived Mast Cells* , 2004, Journal of Biological Chemistry.
[11] R. Black,et al. TACE/ADAM-17 enzymatic activity is increased in response to cellular stimulation. , 2003, Biochemical and biophysical research communications.
[12] J. Arribas,et al. Protein ectodomain shedding. , 2002, Chemical reviews.
[13] J. Baselga,et al. Metalloprotease-dependent Protransforming Growth Factor-α Ectodomain Shedding in the Absence of Tumor Necrosis Factor-α-converting Enzyme* , 2001, The Journal of Biological Chemistry.
[14] G. Imokawa,et al. The mechanism of epidermal hyperpigmentation in dermatofibroma is associated with stem cell factor and hepatocyte growth factor expression. , 2001, The Journal of investigative dermatology.
[15] V. Broudy,et al. The fifth immunoglobulin-like domain of the Kit receptor is required for proteolytic cleavage from the cell surface. , 2001, Cytokine.
[16] M. Kashima,et al. Serum levels of soluble stem cell factor and soluble KIT are elevated in patients with atopic dermatitis and correlate with the disease severity , 2001, The British journal of dermatology.
[17] V. Broudy,et al. Soluble Kit receptor blocks stem cell factor bioactivity in vitro. , 2001, Leukemia research.
[18] A. Hachiya,et al. The paracrine role of stem cell factor/c-kit signaling in the activation of human melanocytes in ultraviolet-B-induced pigmentation. , 2001, The Journal of investigative dermatology.
[19] G. Imokawa,et al. Intracellular Signaling Mechanisms Leading to Synergistic Effects of Endothelin-1 and Stem Cell Factor on Proliferation of Cultured Human Melanocytes , 2000, The Journal of Biological Chemistry.
[20] L. Scott,et al. Soluble stem cell factor receptor (CD117) and IL-2 receptor alpha chain (CD25) levels in the plasma of patients with mastocytosis: relationships to disease severity and bone marrow pathology. , 2000, Blood.
[21] A. Joachimiak,et al. Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[22] Inoue,et al. Modulation of melanocyte‐stimulating hormone receptor expression on normal human melanocytes: evidence for a regulatory role of ultraviolet B, interleukin‐1α, interleukin‐1β, endothelin‐1 and tumour necrosis factor‐α , 1998 .
[23] J. A. Burch,et al. The SCF/KIT Pathway Plays a Critical Role in the Control of Normal Human Melanocyte Homeostasis , 1998 .
[24] M. B. Davis,et al. Endothelin-1 is a paracrine growth factor that modulates melanogenesis of human melanocytes and participates in their responses to ultraviolet radiation. , 1998, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[25] S. Nishikawa,et al. Murine Cutaneous Mastocytosis and Epidermal Melanocytosis Induced by Keratinocyte Expression of Transgenic Stem Cell Factor , 1998, The Journal of experimental medicine.
[26] H. Kawasaki,et al. Serum soluble c‐kit receptor and expression of c‐kit protein and mRNA in acute myeloid leukemia , 1998, European journal of haematology.
[27] D. Gawkrodger,et al. alpha-MSH and melanogenesis in normal human adult melanocytes. , 1998, Pigment cell research.
[28] V. Broudy,et al. Stem cell factor and hematopoiesis. , 1997, Blood.
[29] G. Imokawa,et al. The role of endothelin-1 in epidermal hyperpigmentation and signaling mechanisms of mitogenesis and melanogenesis. , 1997, Pigment cell research.
[30] M. Asaka,et al. Low levels of serum soluble c-kit relates to delayed engraftment after bone marrow transplantation. , 1997, Leukemia and Lymphoma.
[31] Nicole Nelson,et al. A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells , 1997, Nature.
[32] J. Ortonne,et al. Nitric oxide produced by ultraviolet-irradiated keratinocytes stimulates melanogenesis. , 1997, The Journal of clinical investigation.
[33] A. Chakraborty,et al. Production and release of proopiomelanocortin (POMC) derived peptides by human melanocytes and keratinocytes in culture: regulation by ultraviolet B. , 1996, Biochimica et biophysica acta.
[34] H. Törmä,et al. Increased expression of inducible nitric oxide synthase in psoriatic skin and cytokine‐stimulated cultured keratinocytes , 1996, The British journal of dermatology.
[35] S. Nishikawa,et al. Distinct stages of melanocyte differentiation revealed by anlaysis of nonuniform pigmentation patterns. , 1996, Development.
[36] B. Gilchrest,et al. Proopiomelanocortin gene product regulation in keratinocytes. , 1996, The Journal of investigative dermatology.
[37] G. Imokawa,et al. Signalling mechanisms of endothelin-induced mitogenesis and melanogenesis in human melanocytes. , 1996, The Biochemical journal.
[38] S. Nishikawa,et al. Effects of monoclonal anti-c-kit antibody (ACK2) on melanocytes in newborn mice. , 1995, The Journal of investigative dermatology.
[39] T. Suda,et al. Soluble c‐kit molecule in serum from healthy individuals and patients with haemopoietic disorders , 1995, British journal of haematology.
[40] B. Czarnetzki,et al. Expression of stem cell factor in cutaneous mastocytosis , 1995, The British journal of dermatology.
[41] G. Imokawa,et al. Endothelin-1 as a new melanogen: coordinated expression of its gene and the tyrosinase gene in UVB-exposed human epidermis. , 1995, The Journal of investigative dermatology.
[42] H. Atkins,et al. Identification and characterization of a soluble c-kit receptor produced by human hematopoietic cell lines. , 1995, Blood.
[43] M. Asaka,et al. Soluble c‐kit levels in acute GVHD after allogeneic bone marrow transplantation , 1995, British journal of haematology.
[44] S. Boyce,et al. Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[45] M. Eisenstein,et al. The fourth immunoglobulin domain of the stem cell factor receptor couples ligand binding to signal transduction , 1995, Cell.
[46] H. Serve,et al. Mechanism of down-regulation of c-kit receptor. Roles of receptor tyrosine kinase, phosphatidylinositol 3'-kinase, and protein kinase C. , 1994, The Journal of biological chemistry.
[47] F. Trautinger,et al. Proopiomelanocortin-derived peptides are synthesized and released by human keratinocytes. , 1994, The Journal of clinical investigation.
[48] V. Broudy,et al. Human umbilical vein endothelial cells display high-affinity c-kit receptors and produce a soluble form of the c-kit receptor , 1994 .
[49] E. Huang,et al. The kit-ligand (steel factor) and its receptor c-kit/W: pleiotropic roles in gametogenesis and melanogenesis. , 1993, Development (Cambridge, England). Supplement.
[50] H. Langen,et al. Mechanism of kit ligand, phorbol ester, and calcium-induced down-regulation of c-kit receptors in mast cells. , 1993, The Journal of biological chemistry.
[51] D. Williams,et al. Altered metabolism of mast-cell growth factor (c-kit ligand) in cutaneous mastocytosis. , 1993, The New England journal of medicine.
[52] S. Nishikawa,et al. Interspecies molecular chimeras of kit help define the binding site of the stem cell factor , 1993, Molecular and cellular biology.
[53] M. Brizzi,et al. Soluble c-kit proteins and antireceptor monoclonal antibodies confine the binding site of the stem cell factor. , 1993, The Journal of biological chemistry.
[54] R. Halaban,et al. White mutants in mice shedding light on humans. , 1993, The Journal of investigative dermatology.
[55] G. Imokawa,et al. Endothelins secreted from human keratinocytes are intrinsic mitogens for human melanocytes. , 1992, The Journal of biological chemistry.
[56] S. Lev,et al. Dimerization and activation of the kit receptor by monovalent and bivalent binding of the stem cell factor. , 1992, The Journal of biological chemistry.
[57] D. Williams,et al. The Steel factor. , 1992, Developmental biology.
[58] R. Spritz,et al. Dominant negative and loss of function mutations of the c-kit (mast/stem cell growth factor receptor) proto-oncogene in human piebaldism. , 1992, American journal of human genetics.
[59] C. Heldin,et al. Activation of the human c‐kit product by ligand‐induced dimerization mediates circular actin reorganization and chemotaxis. , 1991, The EMBO journal.
[60] R. Spritz,et al. Mutation of the KIT (mast/stem cell growth factor receptor) protooncogene in human piebaldism. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[61] G. Imokawa,et al. Effects of endothelins on signal transduction and proliferation in human melanocytes. , 1991, The Journal of biological chemistry.
[62] S. Nishikawa,et al. In utero manipulation of coat color formation by a monoclonal anti‐c‐kit antibody: two distinct waves of c‐kit‐dependency during melanocyte development. , 1991, The EMBO journal.
[63] A. Reith,et al. The murine W/c-kit and Steel loci and the control of hematopoiesis. , 1991, Seminars in hematology.
[64] B. Hogan,et al. Embryonic expression of a haematopoietic growth factor encoded by the SI locus and the ligand for c-kit , 1990, Nature.
[65] Y. Yarden,et al. Developmental expression of c-kit, a proto-oncogene encoded by the W locus. , 1990, Development.
[66] R. Halaban,et al. Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes , 1988, The Journal of cell biology.
[67] G. Imokawa,et al. Selective aberration and pigment loss in melanosomes of malignant melanoma cells in vitro by glycosylation inhibitors: premelanosomes as glycoprotein. , 1983, The Journal of investigative dermatology.
[68] G. Imokawa,et al. Loss of melanogenic properties in tyrosinases induced by glucosylation inhibitors within malignant melanoma cells. , 1982, Cancer research.
[69] G. Szabó,et al. Mitotic activity of epidermal melanocytes in UV-irradiated mouse skin. , 1978, The Journal of investigative dermatology.
[70] M. Seiji,et al. Transfer mechanism of melanosomes in epidermal cell culture. , 1976, The Journal of investigative dermatology.
[71] Monika Bzowska,et al. Structure and functions of tumor necrosis factor-alpha converting enzyme. , 2003, Acta biochimica Polonica.
[72] D. Williams,et al. Signaling through the interaction of membrane-restricted stem cell factor and c-kit receptor tyrosine kinase: genetic evidence for a differential role in erythropoiesis. , 1998, Blood.
[73] J. Burn,et al. Novel mutations and deletions of the KIT (steel factor receptor) gene in human piebaldism. , 1995, American journal of human genetics.
[74] J. Wypych,et al. Soluble kit receptor in human serum. , 1995, Blood.
[75] S. Galli,et al. The kit ligand, stem cell factor. , 1994, Advances in immunology.
[76] M. Zamora,et al. Cultured human keratinocytes synthesize and secrete endothelin-1. , 1993, The Journal of investigative dermatology.