Nuclear transport receptor karyopherin-α2 promotes malignant breast cancer phenotypes in vitro
暂无分享,去创建一个
E. Dahl | M. Rose | R. Knüchel | E. Noetzel | J. Bornemann | M. Gajewski
[1] F. Wang,et al. Octamer 4 Small Interfering RNA Results in Cancer Stem Cell-Like Cell Apoptosis , 2012 .
[2] Sven Diederichs,et al. The hallmarks of cancer , 2012, RNA biology.
[3] Yu-Sun Chang,et al. Importin subunit alpha‐2 is identified as a potential biomarker for non‐small cell lung cancer by integration of the cancer cell secretome and tissue transcriptome , 2011, International journal of cancer.
[4] G. Kristiansen,et al. KPNA2 Expression Is an Independent Adverse Predictor of Biochemical Recurrence after Radical Prostatectomy , 2011, Clinical Cancer Research.
[5] H. Kuwano,et al. Significance of Karyopherin-α 2 (KPNA2) Expression in Esophageal Squamous Cell Carcinoma , 2010 .
[6] N. Klugbauer,et al. The Nuclear Import of the Small GTPase Rac1 is Mediated by the Direct Interaction with Karyopherin α2 , 2010, Traffic.
[7] Matthias Ochs,et al. A review of recent methods for efficiently quantifying immunogold and other nanoparticles using TEM sections through cells, tissues and organs. , 2009, Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft.
[8] E. Dahl,et al. Nuclear karyopherin α2 expression predicts poor survival in patients with advanced breast cancer irrespective of treatment intensity , 2008, International journal of cancer.
[9] C Caldas,et al. Proliferation markers and survival in early breast cancer: a systematic review and meta-analysis of 85 studies in 32,825 patients. , 2008, Breast.
[10] E. Dahl,et al. Promoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancer , 2008, BMC Cancer.
[11] A. Regev,et al. An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors , 2008, Nature Genetics.
[12] G. Kristiansen,et al. The extracellular matrix protein ITIH5 is a novel prognostic marker in invasive node-negative breast cancer and its aberrant expression is caused by promoter hypermethylation , 2008, Oncogene.
[13] G. Kristiansen,et al. KPNA2 protein expression in invasive breast carcinoma and matched peritumoral ductal carcinoma in situ , 2007, Virchows Archiv.
[14] I. Petersen,et al. Comparison of gene expression data from human and mouse breast cancers: Identification of a conserved breast tumor gene set , 2007, International journal of cancer.
[15] Ryan E. Mills,et al. Classical Nuclear Localization Signals: Definition, Function, and Interaction with Importin α* , 2007, Journal of Biological Chemistry.
[16] Wen-Lin Kuo,et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. , 2006, Cancer cell.
[17] Christian Pilarsky,et al. Molecular Profiling of Laser-Microdissected Matched Tumor and Normal Breast Tissue Identifies Karyopherin α2 as a Potential Novel Prognostic Marker in Breast Cancer , 2006, Clinical Cancer Research.
[18] A. Clark,et al. Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma , 2005, Cancer.
[19] Yukinori Endo,et al. A Rac switch regulates random versus directionally persistent cell migration , 2005, The Journal of cell biology.
[20] S. Gelling,et al. Systematic identification and molecular characterization of genes differentially expressed in breast and ovarian cancer , 2005, The Journal of pathology.
[21] L. Pemberton,et al. Karyopherins: from nuclear-transport mediators to nuclear-function regulators. , 2004, Trends in cell biology.
[22] D. Goldfarb,et al. Importin α: A multipurpose nuclear-transport receptor , 2004 .
[23] Pamela A. Silver,et al. Nuclear transport and cancer: from mechanism to intervention , 2004, Nature Reviews Cancer.
[24] G. Borisy,et al. Cell Migration: Integrating Signals from Front to Back , 2003, Science.
[25] R. Tibshirani,et al. Repeated observation of breast tumor subtypes in independent gene expression data sets , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[26] M. Hodel,et al. Characterization of the Auto-inhibitory Sequence within the N-terminal Domain of Importin α* , 2003, Journal of Biological Chemistry.
[27] S. Nadler,et al. An intracellular targeted NLS peptide inhibitor of karyopherin α:NF-κB interactions , 2003 .
[28] Michael Karin,et al. NF-κB in cancer: from innocent bystander to major culprit , 2002, Nature Reviews Cancer.
[29] L. Thiberville,et al. Inhibition of tumor growth and metastatic spreading by overexpression of inter‐alpha‐trypsin inhibitor family chains , 2002, International journal of cancer.
[30] G. Blobel,et al. Karyopherins and nuclear import. , 2001, Current opinion in structural biology.
[31] G. Christofori,et al. Cell adhesion in tumor invasion and metastasis: loss of the glue is not enough. , 2001, Biochimica et biophysica acta.
[32] D. Helfman,et al. Cytoskeletal changes in cell transformation and tumorigenesis. , 2001, Current opinion in genetics & development.
[33] Christian A. Rees,et al. Molecular portraits of human breast tumours , 2000, Nature.
[34] Jiandong Chen,et al. Nuclear exclusion of p53 in a subset of tumors requires MDM2 function , 2000, Oncogene.
[35] B. Rayet,et al. Aberrant rel/nfkb genes and activity in human cancer , 1999, Oncogene.
[36] D. Görlich. Transport into and out of the cell nucleus , 1998, The EMBO journal.
[37] G. Curigliano,et al. Prognostic significance of cytoplasmic p53 overexpression in colorectal cancer. An immunohistochemical analysis. , 1996, European journal of cancer.
[38] R. Kreienberg,et al. Subcellular localization of accumulated p53 in ovarian cancer cells. , 1996, Gynecologic oncology.
[39] D. Lauffenburger,et al. Cell Migration: A Physically Integrated Molecular Process , 1996, Cell.
[40] A. Ashworth,et al. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1 , 1995, Science.
[41] G. Blobel,et al. The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex , 1995, Cell.
[42] D. Lane,et al. Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasms , 1990, The Journal of pathology.
[43] H. Kuwano,et al. Significance of karyopherin-{alpha} 2 (KPNA2) expression in esophageal squamous cell carcinoma. , 2010, Anticancer research.
[44] A. Hall,et al. Cell migration: Rho GTPases lead the way. , 2004, Developmental biology.
[45] D. Goldfarb,et al. Importin alpha: a multipurpose nuclear-transport receptor. , 2004, Trends in cell biology.
[46] S. Nadler,et al. An intracellular targeted NLS peptide inhibitor of karyopherin alpha:NF-kappa B interactions. , 2003, Biochemical and biophysical research communications.
[47] Michael Karin,et al. NF-kappaB in cancer: from innocent bystander to major culprit. , 2002, Nature reviews. Cancer.
[48] A. Brunet,et al. [MAP kinase module: role in the control of cell proliferation]. , 1995, Comptes rendus des seances de la Societe de biologie et de ses filiales.