论文信息 - Role of CSF-CRP in Diagnosis of Meningitis

Role of CSF-CRP in Diagnosis of Meningitis

Background: Meningitis is an acute inflammation of the membranes covering brain and spinal cord. Meningitis may be caused by infection with virus, bacteria, fungus etc. Diagnosis of meningitis and differentiating between various types of meningitis remains a challenge for the physician. Aim: The aim of this study is to examine the role of CSF-CRP in diagnosis of meningitis. Material and method: A total of 60 children with meningitis and suspected meningitis were included in the study. Detailed history was taken and clinical examination was done. Routine CSF examination included cell count, protein, sugar, gram stain, culture, ADA and chloride levels estimation. The Level of C Reactive Protein in CSF of all meningitis groups was recorded. Result: Out of 60 cases, clinically and by CSF examination, tuberculous meningitis was diagnosed in 25 cases (42 %), followed by bacterial meningitis, 20 cases (33 %). 8 (13 %) cases were diagnosed viral meningitis and 7 children (12 %) were normal. A statistically significant association between CSF CRP positivity and Pyogenic meningitis was seen. Conclusion: CSF-CRP levels can be used as anearly diagnostic tool or confirmatory test in meningitis. It helps in differentiating various types of meningitis.

S. Chaudhary | A. Chaudhary

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