TA205, an anti‐talin monoclonal antibody, inhibits integrin–talin interaction
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[1] Junichi Takagi,et al. Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[2] Stephanie Kreis,et al. A Fluorescence Cell Biology Approach to Map the Second Integrin-binding Site of Talin to a 130-Amino Acid Sequence within the Rod Domain* , 2004, Journal of Biological Chemistry.
[3] J. Qin,et al. Membrane-mediated structural transitions at the cytoplasmic face during integrin activation , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[4] R. Liddington,et al. Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation , 2003, Science.
[5] I. Campbell,et al. Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit. , 2003, Biochemistry.
[6] R. Liddington,et al. Structural determinants of integrin recognition by talin. , 2003, Molecular cell.
[7] Richard O Hynes,et al. Integrins Bidirectional, Allosteric Signaling Machines , 2002, Cell.
[8] Jun Qin,et al. A Structural Mechanism of Integrin αIIbβ3 “Inside-Out” Activation as Regulated by Its Cytoplasmic Face , 2002, Cell.
[9] David A. Calderwood,et al. The Phosphotyrosine Binding-like Domain of Talin Activates Integrins* , 2002, The Journal of Biological Chemistry.
[10] S. Lam,et al. Localization of an Integrin Binding Site to the C Terminus of Talin* , 2001, The Journal of Biological Chemistry.
[11] B. Yaspan,et al. Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain. , 2001, The Journal of biological chemistry.
[12] Toshio Hakoshima,et al. Structural basis of the membrane‐targeting and unmasking mechanisms of the radixin FERM domain , 2000, The EMBO journal.
[13] P. Karplus,et al. Structure of the ERM Protein Moesin Reveals the FERM Domain Fold Masked by an Extended Actin Binding Tail Domain , 2000, Cell.
[14] R. Hynes,et al. The Talin Head Domain Binds to Integrin β Subunit Cytoplasmic Tails and Regulates Integrin Activation* , 1999, The Journal of Biological Chemistry.
[15] S. Lam,et al. Identification of a talin-binding site in the integrin beta(3) subunit distinct from the NPLY regulatory motif of post-ligand binding functions. The talin n-terminal head domain interacts with the membrane-proximal region of the beta(3) cytoplasmic tail. , 1999, The Journal of biological chemistry.
[16] K. Pestonjamasp,et al. Regulation of F-actin binding to platelet moesin in vitro by both phosphorylation of threonine 558 and polyphosphatidylinositides. , 1999, Molecular biology of the cell.
[17] S. Aota,et al. Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies , 1997, The Journal of Biological Chemistry.
[18] S. Barry,et al. Monoclonal antibodies recognizing the N- and C-terminal regions of talin disrupt actin stress fibers when microinjected into human fibroblasts. , 1997, Cell motility and the cytoskeleton.
[19] S. Aota,et al. Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory anti-alpha5 and anti-beta1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the alpha5 subunit. , 1997, The Journal of biological chemistry.
[20] Tina M. Leisner,et al. Direct Binding of the Platelet Integrin αIIbβ3 (GPIIb-IIIa) to Talin , 1996, The Journal of Biological Chemistry.
[21] W. Goldmann,et al. Native talin is a dumbbell-shaped homodimer when it interacts with actin. , 1994, Journal of structural biology.
[22] Sarah E. Ades,et al. Sequence and domain structure of talin , 1990, Nature.
[23] C. Otey,et al. Characterization of monoclonal antibodies to chicken gizzard talin. , 1990, Hybridoma.
[24] K. Burridge,et al. Detection of metavinculin in human platelets using a modified talin overlay assay. , 1989, European journal of cell biology.
[25] B. Paschal,et al. Properties of talin from chicken gizzard smooth muscle. , 1987, The Journal of biological chemistry.
[26] M. Beckerle,et al. Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage , 1986, Nature.