The management of dyspepsia: a systematic review.

[1]  A. Axon,et al.  Is there a rationale for eradication of Helicobacter pylori? Cost-benefit: the case for. , 1998, British medical bulletin.

[2]  A. D. De Schepper,et al.  A double-blind fluoroscopic study of cisapride on gastrointestinal motility in patients with functional dyspepsia. , 1993, Scandinavian journal of gastroenterology. Supplement.

[3]  J. Dent,et al.  Postprandial antropyloroduodenal motility and gastric emptying in gastroparesis--effects of cisapride. , 1994, Gut.

[4]  W. McIlroy,et al.  Should unpublished data be included in meta-analyses? Current convictions and controversies. , 1993, JAMA.

[5]  A. Zinsmeister,et al.  Effect of six weeks of treatment with cisapride in gastroparesis and intestinal pseudoobstruction. , 1989, Gastroenterology.

[6]  P. Malfertheiner,et al.  The association between non‐ulcer dyspepsia and Helicobacter pylori infection , 1994 .

[7]  M. Korman,et al.  Campylobacter pylori--a role in non-ulcer dyspepsia? , 1989, Scandinavian journal of gastroenterology. Supplement.

[8]  M. Hradský,et al.  Effect of pirenzepine in the treatment of non-ulcer dyspepsia. A double-blind study. , 1982, Scandinavian journal of gastroenterology. Supplement.

[9]  L. Sandvik,et al.  The effect of cimetidine in non-ulcer dyspepsia. Experience with a multi-cross-over model. , 1985, Scandinavian journal of gastroenterology.

[10]  I. Wiklund,et al.  Does endoscopy have a positive impact on quality of life in dyspepsia? , 1998, Gastrointestinal endoscopy.

[11]  D. Forman,et al.  Current European concepts in the management of Helicobacter pylori infection. The Maastricht Consensus Report. European Helicobacter Pylori Study Group. , 1997, Gut.

[12]  A. Hasman,et al.  The diagnostic outcome of upper gastrointestinal endoscopy: Are referral source and patient age determining factors? , 1994 .

[13]  A. Johnson.  Controlled Trial of Metoclopramide in the Treatment of Flatulent Dyspepsia , 1971, British medical journal.

[14]  R. Dhiman,et al.  Gastric emptying in patients with non ulcer dyspepsia (dysmotility type). , 1997, Tropical gastroenterology : official journal of the Digestive Diseases Foundation.

[15]  B. Shuter,et al.  Efficacy of cisapride therapy in functional dyspepsia , 1995, Alimentary pharmacology & therapeutics.

[16]  P. Pazzi,et al.  Misoprostol for the treatment of chronic erosive gastritis: a double-blind placebo-controlled trial. , 1994, The American journal of gastroenterology.

[17]  R. Hannon.  Efficacy of cisapride in patients with nonulcer dyspepsia: a placebo-controlled study , 1987 .

[18]  M. Gear,et al.  Endoscopic studies of dyspepsia in a general practice. , 1980, British medical journal.

[19]  H. Adami,et al.  Absence of therapeutic benefit from antacids or cimetidine in non-ulcer dyspepsia. , 1986, The New England journal of medicine.

[20]  N. Kumar,et al.  Controlled therapeutic trial to determine the optimum dose of antacids in duodenal ulcer. , 1984, Gut.

[21]  S. Fullerton,et al.  Management Strategies for Helicobacter pylori-Seropositive Patients with Dyspepsia: Clinical and Economic Consequences , 1997, Annals of Internal Medicine.

[22]  P. Malfertheiner,et al.  Elan study proves symptomatic benefit of Helicobacter pylori eradication in functional dyspepsia(FD) , 2000 .

[23]  Roger Jones,et al.  Dyspeptic symptoms in the community. , 1989, Gut.

[24]  R. Aggarwal,et al.  Healing of chronic antral gastritis: effect of sucralfate and colloidal bismuth subcitrate. , 1996, Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology.

[25]  F. Rocca,et al.  Cimetidine vs antacids in non-ulcer dyspepsia , 1986 .

[26]  H. Devlin,et al.  Appropriate use of upper gastrointestinal endoscopy--a prospective audit. Steering Group of the Upper Gastrointestinal Endoscopy Audit Committee. , 1994, Gut.

[27]  W. V. Van Ganse,et al.  Relief of epigastric pain in nonulcer dyspepsia: controlled trial of the promotility drug cisapride. , 1989, Clinical therapeutics.

[28]  S. Lam,et al.  Antacids. Indications and limitations. , 1994, Drugs.

[29]  A. Ippoliti,et al.  A controlled trial of metoclopramide in symptomatic gastroesophageal reflux. , 1977, The New England journal of medicine.

[30]  G. Mela,et al.  Open access endoscopy: a large-scale analysis of its use in dyspeptic patients. , 1993, Journal of clinical gastroenterology.

[31]  G. H. Steele.  Cost-effective management of dyspepsia and gastroesophageal reflux disease. , 1996, Primary care.

[32]  R. J. Hayes,et al.  Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. , 1995, JAMA.

[33]  R. McCallum,et al.  Cisapride in the Long-Term Treatment of Chronic Gastroparesis: A 2-Year Open-Label Study , 1997, The Journal of international medical research.

[34]  F. Hobbs,et al.  Effect of Helicobacter pylori eradication therapy on dyspeptic symptoms in primary care. , 1996, Family practice.

[35]  C. Goethals,et al.  Cisapride in the treatment of chronic functional dyspepsia: results of a double-blind, placebo-controlled, crossover study , 1987 .

[36]  S. Müller-lissner,et al.  Treatment of chronic constipation with cisapride and placebo. , 1987, Gut.

[37]  R. Watson,et al.  Open access gastroscopy — 3 year experience of a new service , 1998, Irish Journal of Medical Science.

[38]  H. Iishi,et al.  Gastric emptying and gastrointestinal symptoms in patients with atrophic gastritis and the effects of domperidone. , 1989, Scandinavian journal of gastroenterology.

[39]  A. Fraser,et al.  Diagnostic tests for Helicobacter pylori--can they help select patients for endoscopy? , 1996, The New Zealand medical journal.

[40]  C D Schleck,et al.  Dyspepsia and dyspepsia subgroups: a population-based study. , 1992, Gastroenterology.

[41]  K. Bodger,et al.  Prescribing patterns for dyspepsia in primary care: a prospective study of selected general practitioners , 1996, Alimentary pharmacology & therapeutics.

[42]  R. McCallum,et al.  Metoclopramide: pharmacology and clinical application. , 1983, Annals of internal medicine.

[43]  E. A. Ayoola,et al.  Non-ulcer dyspepsia in Nigerians clinical and therapeutic results. , 1986, Scandinavian journal of gastroenterology. Supplement.

[44]  A. Berstad,et al.  Effect of cimetidine in patients with non-ulcer dyspepsia and erosive prepyloric changes. , 1985, Scandinavian journal of gastroenterology.

[45]  M. Rutter,et al.  The one-stop dyspepsia clinic—an alternative to open-access endoscopy for patients with dyspepsia , 1998, Journal of the Royal Society of Medicine.

[46]  R. N. Brogden,et al.  Domperidone , 1982, Drugs.

[47]  S. Naik,et al.  Effect of high dose liquid antacids on symptoms and endoscopic and histological changes in gastroduodenal mucosa in non-ulcer dyspepsia. , 1988, Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology.

[48]  P. Bytzer,et al.  Placebo-Controlled Trial of Cisapride and Nizatidine in Unselected Patients With Functional Dyspepsia , 1998, American Journal of Gastroenterology.

[49]  A. Al-Quorain,et al.  A double-blind, randomized, placebo-controlled trial of cisapride in Saudi Arabs with functional dyspepsia. , 1995, Scandinavian journal of gastroenterology.

[50]  S. Brown,et al.  Open access gastroscopy: too much to swallow? , 1990, BMJ.

[51]  I. Kagevi,et al.  Endoscopic findings and diagnoses in unselected dyspeptic patients at a primary health care center. , 1989, Scandinavian journal of gastroenterology.

[52]  W. Thompson,et al.  Dyspepsia: is a trial of therapy appropriate? , 1995, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[53]  R. Brook,et al.  Overuse of upper gastrointestinal endoscopy in a country with open-access endoscopy: a prospective study in primary care. , 1997, Gastrointestinal endoscopy.

[54]  K. Gibiński.  Step by step towards the natural history of peptic ulcer disease. , 1983, Journal of Clinical Gastroenterology.

[55]  P. Jalovaara,et al.  Sucralfate versus placebo in treatment of non-ulcer dyspepsia. , 1987, The American journal of medicine.

[56]  J. van Dam,et al.  Prospective screening of dyspeptic patients by Helicobacter pylori serology. , 1996, Gastrointestinal endoscopy.

[57]  C. Wastell,et al.  A controlled trial of cimetidine for the treatment of nonulcer dyspepsia. , 1986, Journal of clinical gastroenterology.

[58]  T C Chalmers,et al.  Meta-analysis of clinical trials as a scientific discipline. I: Control of bias and comparison with large co-operative trials. , 1987, Statistics in medicine.

[59]  D. Schlich,et al.  A double-blind crossover trial of domperidone in chronic postprandial dyspepsia. , 1979, Postgraduate medical journal.

[60]  R. Jones.  Upper gastrointestinal endoscopy--a view from general practice. , 1986, The Journal of the Royal College of General Practitioners.

[61]  J. H. Baron,et al.  Acid, pepsin, and mucus secretion in patients with gastric and duodenal ulcer before and after colloidal bismuth subcitrate (De-Nol). , 1986, Gut.

[62]  George Davey Smith,et al.  meta-analysis bias in location and selection of studies , 1998 .

[63]  T. Northfield,et al.  Serology for Helicobacter pylori compared with symptom questionnaires in screening before direct access endoscopy. , 1995, Gut.

[64]  P. Funch‐jensen,et al.  Sucralfate in gastritis. , 1987, Scandinavian journal of gastroenterology. Supplement.

[65]  T. Hersh,et al.  Metoclopramide therapy in fifty-five patients with delayed gastric emptying. , 1980, The American journal of gastroenterology.

[66]  T. Rokkas,et al.  Non-ulcer dyspepsia and short term De-Nol therapy: a placebo controlled trial with particular reference to the role of Campylobacter pylori. , 1988, Gut.

[67]  A. Ferguson,et al.  A limited, direct access endoscopy service for general practitioners. , 1982, Health bulletin.

[68]  R. Brignoli,et al.  Cisapride or cimetidine in the treatment of functional dyspepsia. Results of a double-blind, randomized, Swiss multicentre study. , 1994, Scandinavian journal of gastroenterology.

[69]  N. Talley,et al.  Non‐ulcer dyspepsia: myths and realities , 1991, Alimentary pharmacology & therapeutics.

[70]  E. Rossi,et al.  Prevalence of Helicobacter pylori infection and related gastroduodenal lesions in spouses of Helicobacter pylori positive patients with duodenal ulcer. , 1996, Gut.

[71]  B. Marshall,et al.  The future of Helicobacter pylori eradication: a personal perspective , 1997, Alimentary Pharmacology and Therapeutics.

[72]  R. Hunt,et al.  What role does Helicobacter pylori play in dyspepsia and nonulcer dyspepsia? Arguments for and against H. pylori being associated with dyspeptic symptoms. , 1997, Gastroenterology.

[73]  K. Haarmann,et al.  A double-blind study of domperidone in the symptomatic treatment of chronic post-prandial upper gastrointestinal distress. , 1979, Postgraduate medical journal.

[74]  J. Malagelada,et al.  Binding properties in vitro of antacids for conjugated bile acids. , 1977, Gastroenterology.

[75]  J. Dunbar,et al.  New patients presenting to their GP with dyspepsia: does Helicobacter pylori eradication minimise the cost of managing these patients? , 1997, International journal of clinical practice.

[76]  O. B. Schaffalitzky de Muckadell,et al.  Management of dyspeptic patients in primary care. Value of the unaided clinical diagnosis and of dyspepsia subgrouping. , 1998, Scandinavian journal of gastroenterology.

[77]  P. Graham.  Upper gastrointestinal endoscopy. Findings in an isolated rural general practice. , 1989, Australian Family Physician.

[78]  R. Logan,et al.  The epidemiology and transmission of Helicobacter pylori infection in children. , 1995, Alimentary pharmacology & therapeutics.

[79]  N. Talley,et al.  Non-ulcer dyspepsia: potential causes and pathophysiology. , 1988, Annals of internal medicine.

[80]  A. Levi,et al.  Long term acid suppressing treatment in general practice , 1994, BMJ.

[81]  J. Y. Kang,et al.  Effect of colloidal bismuth subcitrate on symptoms and gastric histology in non-ulcer dyspepsia. A double blind placebo controlled study. , 1990, Gut.

[82]  D. Mwakyusa.  Effects of domperidone in dyspepsia. , 1987, East African medical journal.

[83]  J. Kellow,et al.  Life stress and non-ulcer dyspepsia: a case-control study. , 1991, Journal of psychosomatic research.

[84]  Hsiao‐Bai Yang,et al.  Long-term outcome of triple therapy in Helicobacter pylori-related nonulcer dyspepsia: a prospective controlled assessment. , 1996, The American journal of gastroenterology.

[85]  G. Creytens.  Effect of the non-antidopaminergic drug cisapride on postprandial nausea , 1984 .

[86]  J. Malagelada,et al.  Does Helicobacter pylori infection increase gastric sensitivity in functional dyspepsia? , 1995, Gut.

[87]  P. Pikkarainen,et al.  Etiology of dyspepsia: four hundred unselected consecutive patients in general practice. , 1995, Scandinavian journal of gastroenterology.

[88]  S. Harasawa,et al.  Dyspepsia and dyspepsia subgroups in Japan: symptom profiles and experience with cisapride. , 1993, Scandinavian journal of gastroenterology. Supplement.

[89]  P. Miskovitz,et al.  Clinical evaluation of domperidone in the treatment of chronic postprandial idiopathic upper gastrointestinal distress. , 1981, The American journal of gastroenterology.

[90]  T. Rokkas,et al.  Campylobacter pylori and non-ulcer dyspepsia. , 1987, The American journal of gastroenterology.

[91]  J R Bennett,et al.  The endoscopic assessment of esophagitis: a progress report on observer agreement. , 1996, Gastroenterology.

[92]  O. Bonnevie,et al.  Controlled clinical trial of treatment with cimetidine for non-ulcer dyspepsia. , 2009, Acta medica Scandinavica.

[93]  S. Misra,et al.  Sucralfate versus ranitidine in non-ulcer dyspepsia: results of a prospective, randomized, open, controlled trial. , 1992, Indian Journal of Gastroenterology.

[94]  A. Sonnenberg.  Cost-benefit analysis of testing for Helicobacter pylori in dyspeptic subjects. , 1996, The American journal of gastroenterology.

[95]  S. Broor,et al.  Cimetidine in the treatment of non-ulcer dyspepsia: results of a randomized double-blind, placebo-controlled study. , 1989, Current medical research and opinion.

[96]  O. B. Schaffalitzky de Muckadell,et al.  Efficacy and outcome of an open access endoscopy service. , 1991, Danish medical bulletin.

[97]  O. Flaten,et al.  The multi-crossover model for classifying patients as responders to a given treatment. , 1991, Scandinavian journal of gastroenterology.

[98]  T. Abell,et al.  Effect of cisapride therapy for severe dyspepsia on gastrointestinal symptoms and quality of life. , 1993, Scandinavian journal of gastroenterology. Supplement.

[99]  P. Ranløv,et al.  Antacid treatment of duodenal ulcer. , 2009, Acta medica Scandinavica.

[100]  J. Malagelada,et al.  Manometric evaluation of functional upper gut symptoms. , 1985, Gastroenterology.

[101]  A. Lonardo,et al.  Are routine duodenal and antral biopsies useful in the management of "functional" dyspepsia? A diagnostic and therapeutic study. , 1993, Journal of clinical gastroenterology.

[102]  Rosemary K Piquette.  Torsade De Pointes Induced by Cisapride/Clarithromycin Interaction , 1999, The Annals of pharmacotherapy.

[103]  A. Axon.  Duodenal ulcer: the villain unmasked? , 1991, BMJ.

[104]  J. Parsonnet.  Helicobacter pylori and gastric cancer. , 1993, Gastroenterology clinics of North America.

[105]  A. Thomson,et al.  A double-blind randomized study of cisapride in the treatment of nonulcer dyspepsia. The Canadian Cisapride Nud Study Group. , 1997, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

[106]  M. Teh,et al.  Effect of cisapride on functional dyspepsia in patients with and without histological gastritis: A double‐blind placebo‐controlled trial , 1997, Journal of gastroenterology and hepatology.

[107]  P. Funch‐jensen,et al.  Controlled clinical trial with sucralfate in the treatment of macroscopic gastritis. , 1989, Scandinavian journal of gastroenterology.

[108]  J. Dent,et al.  Healing and relapse of severe peptic esophagitis after treatment with omeprazole. , 1988, Gastroenterology.

[109]  J. Freston.  Emerging strategies for managing peptic ulcer disease. , 1994, Scandinavian journal of gastroenterology. Supplement.

[110]  S. Passaretti,et al.  Effect of long-term oral therapy with cisapride in reflux antral gastritis: results of a double-blind placebo-controlled trial , 1990 .

[111]  L. O’Neill,et al.  Uncensored open access gastroscopy — limited resources — unlimited demand , 1998, Irish journal of medical science.

[112]  J. Knottnerus,et al.  Discriminant value of symptoms in patients with dyspepsia. , 1994, The Journal of family practice.

[113]  R. McCallum,et al.  The effect of chronic oral domperidone therapy on gastrointestinal symptoms, gastric emptying, and quality of life in patients with gastroparesis. , 1997, The American journal of gastroenterology.

[114]  E. Boyle,et al.  Is Helicobacter pylori associated with non-ulcer dyspepsia and will eradication improve symptoms? A meta-analysis , 1999, BMJ.

[115]  S. Hadi.  Clinical investigation of ranitidine in patients with gastritis. , 1989, Clinical therapeutics.

[116]  N. Talley,et al.  Review article: functional dyspepsia—should treatment be targeted on disturbed physiology? , 1995, Alimentary pharmacology & therapeutics.

[117]  H. Leufkens,et al.  A prospective follow‐up study of 5669 users of lansoprazole in daily practice , 1997, Alimentary pharmacology & therapeutics.

[118]  R. Vargas,et al.  The effect of various dose regimens of famotidine on basal nocturnal and meal–stimulated gastric secretion , 1987, Clinical pharmacology and therapeutics.

[119]  S. Zuberi,et al.  Lack of therapeutic effect of cimetidine in non-ulcer dyspepsia. , 1988, JPMA. The Journal of the Pakistan Medical Association.

[120]  M. Clarke,et al.  Identifying relevant studies for systematic reviews , 1995, BMJ.

[121]  W. Corbett,et al.  What happens to patients following open access gastroscopy? An outcome study from general practice. , 1994, The British journal of general practice : the journal of the Royal College of General Practitioners.

[122]  Miwa,et al.  Cure of Helicobacter pylori infection does not improve symptoms in non‐ulcer dyspepsia patients—a double‐blind placebo‐controlled study , 2000, Alimentary pharmacology & therapeutics.

[123]  R. Brummer,et al.  The effect of a single rectal dose of cisapride on delayed gastric emptying , 1997, Alimentary pharmacology & therapeutics.

[124]  M. Gear,et al.  Study of Dyspepsia in a General Practice as Assessed by Endoscopy and Radiology , 1974, British medical journal.

[125]  S. Gorbach.  Bismuth therapy in gastrointestinal diseases. , 1990, Gastroenterology.

[126]  G. Lux,et al.  Treatment of duodenal ulcer with low-dose antacids. , 1986, Scandinavian journal of gastroenterology.

[127]  H. Iishi,et al.  Effecf of treatment with cisapride alone or in combination with domperidone on gastric emptying and gastrointestinal symptoms in dyspeptic patients , 1992, Alimentary pharmacology & therapeutics.

[128]  J. Misiewicz,et al.  Open-access endoscopy service for general practitioners. , 1979, British medical journal.

[129]  A. Klovning.  Diagnostic methods in dyspepsia: the usefulness of upper abdominal ultrasound and gastroscopy. , 1998, Scandinavian journal of primary health care.

[130]  A. Verbeek,et al.  Management in general practice of patients with persistent dyspepsia. A decision analysis. , 1997, Journal of clinical gastroenterology.

[131]  C. O'Morain,et al.  Effect of treatment on Campylobacter pylori in peptic disease: a randomised prospective trial. , 1988, Gut.

[132]  R. Smallwood,et al.  Human antroduodenal motility, pyloric closure, and domperidone. , 1984, Scandinavian journal of gastroenterology. Supplement.

[133]  A H Briggs,et al.  Handling uncertainty when performing economic evaluation of healthcare interventions. , 1999, Health technology assessment.

[134]  B. M. Brock,et al.  Scoring system to improve cost effectiveness of open access endoscopy. , 1984, British medical journal.

[135]  M. Osnes,et al.  Ranitidine effectively relieves symptoms in a subset of patients with functional dyspepsia. , 1997, Scandinavian journal of gastroenterology.

[136]  A. Prinzie,et al.  Symptomatic treatment of non-ulcer dyspepsia with cimetidine , 1985 .

[137]  R. Tallis,et al.  Metoclopramide and tardive dyskinesia in the elderly. , 1984, British medical journal.

[138]  O. Nyrén,et al.  Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability over time. , 1995, Gastroenterology.

[139]  M. Comberlato,et al.  Drug Treatment of Functional Dyspepsia: A Meta‐Analysis of Randomized Controlled Clinical Trials , 1989, Journal of clinical gastroenterology.

[140]  G. Goulis,et al.  EFFECT OF CISAPRIDE IN NONULCER DYSPEPSIA : A PLACEBO-CONTROLLED TRIAL , 1991 .

[141]  N. Talley,et al.  Should antibiotic treatment of Helicobacter-positive patients with non‐ulcer dyspepsia now be recommended? , 1998, European Journal of Gastroenterology and Hepathology.

[142]  P. Unge.  What other regimens are under investigation to treat Helicobacter pylori infection? , 1997, Gastroenterology.

[143]  C. Prakash,et al.  Cisapride. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use as a prokinetic agent in gastrointestinal motility disorders. , 1988, Drugs.

[144]  R. Hunt,et al.  Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis. , 1997, Gastroenterology.

[145]  R. Vargas,et al.  Comparison of effects of oral and intravenous famotidine on inhibition of nocturnal gastric acid secretion. , 1986, The American journal of medicine.

[146]  Breslin,et al.  Screening for Helicobacter pylori in young dyspeptic patients referred for investigation—endoscopy for those who test negative , 1998, Alimentary pharmacology & therapeutics.

[147]  A. Axon,et al.  Validation of a rapid whole blood test for diagnosing Helicobacter pylori infection , 1997, BMJ.

[148]  A. Li,et al.  Antibacterial treatment of gastric ulcers associated with Helicobacter pylori. , 1995, The New England journal of medicine.

[149]  J. Severens,et al.  Review article: symptom improvement through eradication of Helicobacter pylori in patients with non‐ulcer dyspepsia , 1996, Alimentary pharmacology & therapeutics.

[150]  R. Hunt,et al.  Is there an optimal degree of acid suppression for healing of duodenal ulcers? A model of the relationship between ulcer healing and acid suppression. , 1990, Gastroenterology.

[151]  A. Berstad,et al.  Low-dose antacids and pirenzepine in the treatment of patients with non-ulcer dyspepsia and erosive prepyloric changes. A randomized, double-blind, placebo-controlled trial. , 1988, Scandinavian journal of gastroenterology.

[152]  I. Macintyre.  Open-access endoscopy for general practitioners. , 1988, Practitioner.

[153]  J. Behar,et al.  Cimetidine in the treatment of symptomatic gastroesophageal reflux: a double blind controlled trial. , 1978, Gastroenterology.

[154]  A. Axon,et al.  Screening dyspepsia by serology to Helicobacter pylori , 1991, The Lancet.

[155]  A. Miller,et al.  A COMPARISON OF CONTROLLED RELEASE METOCLOPRAMIDE AND DOMPERIDONE IN THE TREATMENT OF NAUSEA AND VOMITING , 1991, The British journal of clinical practice.

[156]  D. Russell,et al.  “Open‐access” endoscopy for general practitioners: Experience of a private gastrointestinal clinic , 1986, The Medical journal of Australia.

[157]  M. Deruyttere,et al.  Cisapride in the management of chronic functional dyspepsia: a multicenter, double-blind, placebo-controlled study. , 1987, Clinical therapeutics.

[158]  R. Kaplan.  Modern methods of searching the medical literature. , 1993, The Medical journal of Australia.

[159]  J. Primrose,et al.  Pain provocation test in peptic duodenitis. , 1983, Gastrointestinal endoscopy.

[160]  J. Misiewicz,et al.  Evaluation of one-visit endoscopic clinic for patients with dyspepsia. , 1979, British medical journal.

[161]  B. Delaney,et al.  Near patient tests for Helicobacter pylori in primary care: How accurate do thev need to be? , 1998 .

[162]  P. Bytzer.  Diagnosing dyspepsia: any controversies left? , 1996, Gastroenterology.

[163]  W. Schlippert.  Cimetidine. H2-receptor blockade in gastrointestinal disease. , 1978, Archives of internal medicine.

[164]  O. Nyrén.  Secretory abnormalities in functional dyspepsia. , 1991, Scandinavian journal of gastroenterology. Supplement.

[165]  I. Fumagalli,et al.  Cisapride versus metoclopramide in the treatment of functional dyspepsia. A double-blind comparative trial. , 1994, Scandinavian journal of gastroenterology.

[166]  P. Fidalgo,et al.  Cisapride compared with ranitidine in the treatment of functional dyspepsia. , 1995, European journal of gastroenterology & hepatology.

[167]  J. Elashoff,et al.  Healing of duodenal ulcer with an antacid regimen. , 1977, The New England journal of medicine.

[168]  S. J. Roberts,et al.  Prescribing of antacids and ulcer‐healing drugs in primary care in the north of England , 1995, Alimentary pharmacology & therapeutics.

[169]  M. McCullagh,et al.  IMPACT OF HELICOBACTER PYLORI ERADICATION ON THE PRESCRIBING OF ULCER-HEALING DRUGS IN THE TREATMENT OF PEPTIC ULCER DISEASE IN GENERAL PRACTICE , 1997 .

[170]  A. Blum,et al.  Curing Helicobacter pylori infection in patients with duodenal ulcer may provoke reflux esophagitis. , 1997, Gastroenterology.

[171]  J. Freston.  Cimetidine. I. Developments, pharmacology, and efficacy. , 1982, Annals of internal medicine.

[172]  E. El-Omar,et al.  A substantial proportion of non-ulcer dyspepsia patients have the same abnormality of acid secretion as duodenal ulcer patients. , 1995, Gut.

[173]  J. Gray,et al.  Accuracy of serology for the diagnosis of Helicobacter pylori infection--a comparison of eight kits. , 1996, Journal of clinical pathology.

[174]  J. Christiansen,et al.  Incidence of Perforated and Bleeding Peptic Ulcers before and after the Introduction of H2‐Receptor Antagonists , 1988, Annals of surgery.

[175]  M. Fennerty.  Empirical H2 blocker therapy or prompt endoscopy in the management of dyspepsia. , 1995, Gastrointestinal endoscopy.

[176]  J. Knottnerus,et al.  How well do general practitioners manage dyspepsia? , 1989, The Journal of the Royal College of General Practitioners.

[177]  T. Hausken,et al.  Wide gastric antrum in patients with non-ulcer dyspepsia. Effect of cisapride. , 1992, Scandinavian journal of gastroenterology.

[178]  J. H. Baron,et al.  Randomised double blind controlled study of recurrence of gastric ulcer after treatment for eradication of Helicobacter pylori infection , 1997, BMJ.

[179]  M. Eisner.  Gastrointestinal Effects of Metoclopramide in Man. In Vitro Experiments with Human Smooth Muscle Preparations , 1968, British medical journal.

[180]  L. Rutgeerts,et al.  Oral Domperidone in Chronic Postprandial Dyspepsia , 1979 .

[181]  D. Woods,et al.  Medline and Embase complement each other in literature searches , 1998, BMJ.

[182]  R. Milo.  Non-cholinergic, non-antidopaminergic treatment of chronic digestive symptoms suggestive of a motility disorder: a two-step pilot evaluation of cisapride , 1984 .

[183]  J. Malagelada.  Gastrointestinal motor disturbances in functional dyspepsia. , 1991, Scandinavian journal of gastroenterology. Supplement.

[184]  M. Numans,et al.  How much ulcer is ulcer-like? Diagnostic determinants of peptic ulcer in open access gastroscopy. , 1994, Family practice.

[185]  N. Kalantzis,et al.  Cisapride, metoclopramide, and ranitidine in the treatment of severe nonulcer dyspepsia. , 1992, Clinical therapeutics.

[186]  L. Barbara,et al.  Effect of chronic administration of cisapride on gastric emptying of a solid meal and on dyspeptic symptoms in patients with idiopathic gastroparesis. , 1987, Gut.

[187]  A. Zinsmeister,et al.  Lack of discriminant value of dyspepsia subgroups in patients referred for upper endoscopy. , 1993, Gastroenterology.

[188]  N. D'imperio,et al.  Pirenzepine in non-ulcer dyspepsia. A double-blind, placebo controlled trial. , 1982, Scandinavian journal of gastroenterology. Supplement.

[189]  J. Bernier,et al.  Patients: Effect of a New Gastrokinetic Agent (cisapride) , 2022 .

[190]  C. Venables.  Endoscopy: its diagnostic role in dyspepsia. , 1988, Scandinavian journal of gastroenterology. Supplement.

[191]  A. Wicks,et al.  DO YOUNG PATIENTS WITH DYSPEPSIA NEED INVESTIGATION? , 1988, The Lancet.

[192]  E. Kuipers,et al.  The prevalence of Helicobacter pylori in peptic ulcer disease. , 1995, Alimentary pharmacology & therapeutics.

[193]  G. Gasbarrini,et al.  Pirenzepine in the treatment of benign gastroduodenal diseases. A double-blind controlled clinical trial. , 1979, Scandinavian journal of gastroenterology. Supplement.

[194]  F. J. Hailey,et al.  Evaluation of bismuth subsalicylate in relieving symptoms of indigestion. , 1984, Archives of internal medicine.

[195]  M. Blaser,et al.  Intrafamilial clustering of Helicobacter pylori infection. , 1990, The New England journal of medicine.

[196]  J. H. Baron,et al.  Cost effectiveness of screening for and eradication of Helicobacter pylori in management of dyspeptic patients under 45 years of age , 1996, BMJ.

[197]  D. Coggon,et al.  20 YEARS OF HOSPITAL ADMISSIONS FOR PEPTIC ULCER IN ENGLAND AND WALES , 1981, The Lancet.

[198]  R. Knill-Jones,et al.  Symptomatic benefit from eradicating Helicobacter pylori infection in patients with nonulcer dyspepsia. , 1998, The New England journal of medicine.

[199]  T. Northfield,et al.  The impact of direct access endoscopy, Helicobacter pylori near patient testing and acid suppressants on the management of dyspepsia in general practice. , 1997, International journal of clinical practice.

[200]  I. François,et al.  Nonulcer dyspepsia: effect of the gastrointestinal prokinetic drug cisapride , 1987 .

[201]  J. Hippisley-Cox,et al.  A pilot study of a randomized controlled trial of pragmatic eradication of Helicobactor pylori in primary care. , 1997, The British journal of general practice : the journal of the Royal College of General Practitioners.

[202]  A. Hungin.  Use of an open-access gastroscopy service by a general practice: findings and subsequent specialist referral rate. , 1987, The Journal of the Royal College of General Practitioners.

[203]  J. Barone,et al.  Cisapride: A Gastrointestinal Prokinetic Drug , 1994, The Annals of pharmacotherapy.

[204]  M. V. Van Outryve,et al.  Domperidone for the symptomatic treatment of chronic post-prandial nausea and vomiting. , 1979, Postgraduate medical journal.

[205]  B. Shuter,et al.  Lack of association between gastric emptying of solids and symptoms in nonulcer dyspepsia. , 1989, Journal of clinical gastroenterology.

[206]  T. Hausken,et al.  Gastric antral motility in functional dyspepsia. Effect of mental stress and cisapride. , 1996, Scandinavian journal of gastroenterology.

[207]  R. Spiller,et al.  The urea breath test for Helicobacter pylori. , 1994, Gut.

[208]  P. Both,et al.  Cisapride in functional dyspepsia in general practice. A placebo-controlled, randomized, double-blind study. , 1997 .

[209]  M. Bramble.  Open access endoscopy--a nationwide survey of current practice. , 1992, Gut.

[210]  Nj Talley,et al.  Functional dyspepsia : a classification with guidelines for diagnosis and management , 1991 .

[211]  D. Piper,et al.  Randomized, double-blind, placebo-controlled crossover trial of cimetidine and pirenzepine in nonulcer dyspepsia. , 1986, Gastroenterology.

[212]  A R Jadad,et al.  Guides for reading and interpreting systematic reviews: II. How did the authors find the studies and assess their quality? , 1998, Archives of pediatrics & adolescent medicine.

[213]  D. Graham,et al.  Why do apparently healthy people use antacid tablets? , 1983, The American journal of gastroenterology.

[214]  A. Axon,et al.  Helicobacter pylori: the research explosion , 1995 .

[215]  W. Allum,et al.  Early detection of gastric cancer. , 1990, BMJ.

[216]  A. Komaroff,et al.  Diagnosis and Treatment of Dyspepsia , 1982, Medical decision making : an international journal of the Society for Medical Decision Making.

[217]  S. W. Hosking,et al.  Duodenal ulcer healing by eradication of Helicobacter pylori without anti-acid treatment: randomised controlled trial , 1994, The Lancet.

[218]  P. Malfertheiner,et al.  Chronic erosive gastritis--a therapeutic approach with bismuth. , 1988, Scandinavian journal of gastroenterology. Supplement.

[219]  R. Hopkins,et al.  Relationship between Helicobacter pylori eradication and reduced duodenal and gastric ulcer recurrence: a review. , 1996, Gastroenterology.

[220]  L. Rutgeerts,et al.  Domperidone in the treatment of functional dyspepsia in patients with delayed gastric emptying. , 1979, Postgraduate medical journal.

[221]  S Greenland,et al.  Invited commentary: a critical look at some popular meta-analytic methods. , 1994, American journal of epidemiology.

[222]  P. Schroeder.  Upper gastrointestinal endoscopy at a student health centre. , 1990, Scandinavian journal of primary health care.

[223]  H. Ursin,et al.  Psychotherapy in functional dyspepsia. , 1994, Journal of psychosomatic research.

[224]  N. Talley,et al.  Absence of benefit of eradicating Helicobacter pylori in patients with nonulcer dyspepsia. , 1999, The New England journal of medicine.

[225]  T. Halvorsen,et al.  Cimetidine responders in non-ulcer dyspepsia. , 1988, Scandinavian journal of gastroenterology.

[226]  A. M. Kazi,et al.  A placebo controlled trial of bismuth salicylate in Helicobacter pylori associated gastritis. , 1990, JPMA. The Journal of the Pakistan Medical Association.

[227]  M. Ebell,et al.  Evaluation of the dyspeptic patient: a cost-utility study. , 1997, The Journal of family practice.

[228]  S. Puthucheary,et al.  Helicobacter pylori infection and non-ulcer dyspepsia: the effect of treatment with colloidal bismuth subcitrate. , 1991, Scandinavian journal of gastroenterology.

[229]  R. Heatley.  Open access upper gastrointestinal endoscopy. , 1993, BMJ.

[230]  F. Hobbs,et al.  Dyspepsia in England and Scotland. , 1990, Gut.

[231]  E. Krag.  Non-ulcer dyspepsia introduction: epidemiological data. , 1982, Scandinavian journal of gastroenterology. Supplement.

[232]  W. Rösch.  Cisapride in non-ulcer dyspepsia. Results of a placebo-controlled trial. , 1987, Scandinavian journal of gastroenterology.

[233]  L. Melton,et al.  Gastrointestinal tract symptoms and self-reported abuse: a population-based study. , 1994, Gastroenterology.

[234]  H. Anthoni,et al.  Domperidone in the Treatment of Dyspepsia: A Double-Blind Placebo-Controlled Study , 1979, The Journal of international medical research.

[235]  U. Brodin,et al.  Treatment with cimetidine, antacid, or placebo in patients with dyspepsia of unknown origin. , 1988, Scandinavian journal of gastroenterology.

[236]  A A Stinnett,et al.  Estimating CE Ratios under Second-order Uncertainty , 1997, Medical decision making : an international journal of the Society for Medical Decision Making.

[237]  R. West.  Does blinding of readers affect results of meta-analyses? , 1997, The Lancet.

[238]  J. Saunders,et al.  Dyspepsia: incidence of a non-ulcer disease in a controlled trial of ranitidine in general practice. , 1986, British medical journal.

[239]  M. Bramble,et al.  Reasons for variations in the use of open access gastroscopy by general practitioners. , 1995, Gut.

[240]  A. Axon,et al.  Gastric cancer: a curable disease in Britain. , 1993, BMJ.

[241]  S. Parr.  Chewable cimetidine versus chewable antacid in dyspepsia: which provides faster pain relief? , 1989, Current medical research and opinion.

[242]  S. James,et al.  MeSH terms must be used in Medline searches , 1997, BMJ.

[243]  M. Gear,et al.  A follow-up survey of patients with dyspepsia in one general practice. , 1978, The Journal of the Royal College of General Practitioners.

[244]  M. Hartnett,et al.  Domperidone, a new dopamine antagonist. , 1986, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[245]  F. Halter,et al.  Study with two prokinetics in functional dyspepsia and GORD: domperidone vs. cisapride. , 1997, Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.

[246]  J. Chung.  Cisapride in chronic dyspepsia: results of a double-blind, placebo-controlled trial. , 1993, Scandinavian journal of gastroenterology. Supplement.

[247]  T. Poynard,et al.  Meta-analysis of randomized clinical trials comparing lansoprazole with ranitidine or famotidine in the treatment of acute duodenal ulcer. , 1995, European Journal of Gastroenterology and Hepathology.

[248]  M. Falzon,et al.  Double blind trial of colloidal bismuth subcitrate versus placebo in Helicobacter pylori positive patients with non-ulcer dyspepsia. , 1992, The Italian journal of gastroenterology.

[249]  S. Passaretti,et al.  Longterm oral cisapride improves interdigestive antroduodenal motility in dyspeptic patients. , 1990, Gut.

[250]  G. Cruickshank,et al.  A multi-centre pilot study of tri-potassium di-citrato bismuthate ('De-Nol') in general practice. , 1973, Current medical research and opinion.

[251]  N. Talley.  Drug treatment of functional dyspepsia. , 1991, Scandinavian journal of gastroenterology. Supplement.

[252]  G. Sachs,et al.  The continuing development of gastric acid pump inhibitors , 1993, Alimentary pharmacology & therapeutics.

[253]  A. Thulin,et al.  Endoscopic findings in patients with ulcer-like dyspepsia. , 1985, Scandinavian journal of gastroenterology. Supplement.

[254]  K. Wormsley,et al.  Clinical and endocrine aspects of treatment with ranitidine. , 1981, Scandinavian journal of gastroenterology. Supplement.

[255]  G. Bensi,et al.  Treatment of chronic erosive gastritis: a double-blind trial of pirenzepine and cimetidine. , 1989, Clinical therapeutics.

[256]  O. Bonnevie.  Survival in peptic ulcer , 1978 .

[257]  C. Mcnulty,et al.  Campylobacter pyloridis and associated gastritis: investigator blind, placebo controlled trial of bismuth salicylate and erythromycin ethylsuccinate. , 1986, British medical journal.

[258]  J. Cello,et al.  Lack of effect of treatment for Helicobacter pylori on symptoms of nonulcer dyspepsia. , 1999, Archives of internal medicine.

[259]  S. Lam,et al.  Sucralfate in clinical practice , 1994, Journal of gastroenterology and hepatology.

[260]  M W Gear,et al.  Open-access upper alimentary endoscopy. , 1989, British journal of hospital medicine.

[261]  T. Miwa,et al.  Famotidine in the treatment of gastritis. , 1987, Scandinavian journal of gastroenterology. Supplement.

[262]  B. Thjódleifsson,et al.  Efficacy of sucralfate in treatment of non-ulcer dyspepsia. A double-blind placebo-controlled study. , 1993, Scandinavian journal of gastroenterology.

[263]  W. Rösch.  Efficacy of cisapride in the treatment of epigastric pain and concomitant symptoms in non-ulcer dyspepsia. , 1989, Scandinavian journal of gastroenterology. Supplement.

[264]  C. Mcnulty.  Bismuth subsalicylate in the treatment of gastritis due to Campylobacter pylori. , 1990, Reviews of infectious diseases.

[265]  J. Yardley,et al.  The effect of bismuth subsalicylate on the histologic gastritis seen with Campylobacter pylori: a placebo-controlled, randomized study. , 1989, The American journal of gastroenterology.

[266]  N. Talley.  A critique of therapeutic trials in Helicobacter pylori-positive functional dyspepsia. , 1994, Gastroenterology.

[267]  S. Nundy,et al.  Clinical trial on the effect of domperidone on non-ulcer dyspepsia. , 1986, The Indian journal of medical research.

[268]  M. Bortolotti,et al.  Interdigestive gastroduodenal motility in patients with ulcer-like dyspepsia: effect of ranitidine. , 1992, Hepato-gastroenterology.

[269]  P. Cann,et al.  Open access gastroscopy. Service is efficient and effective. , 1993, BMJ.

[270]  G. Långström,et al.  Omeprazole and H2-receptor antagonists in the acute treatment of duodenal ulcer, gastric ulcer and reflux oesophagitis: a meta-analysis. , 1995, European journal of gastroenterology & hepatology.

[271]  G. Cust,et al.  Changing pattern of admissions and operations for duodenal ulcer , 1989, The British journal of surgery.

[272]  N. Talley,et al.  Initial endoscopy or empirical therapy with or without testing for Helicobacter pylori for dyspepsia: A decision analysis , 1996 .

[273]  P. Malfertheiner,et al.  Gastrointestinal motility in patients with non-ulcer dyspepsia: a role for Helicobacter pylori infection? , 1993, The American journal of gastroenterology.

[274]  B. Bloom,et al.  Alternative Management Strategies for Patients with Suspected Peptic Ulcer Disease , 1995, Annals of Internal Medicine.

[275]  G. Goulis,et al.  Double-Blind Evaluation of Domperidone in Acute Vomiting and Dyspeptic Disorders , 1981, The Journal of international medical research.

[276]  J. Sloan,et al.  Screening for Helicobacter pylori antibody could reduce endoscopy workload in young dyspeptic patients , 1992 .

[277]  O. B. Schaffalitzky de Muckadell,et al.  Predicting endoscopic diagnosis in the dyspeptic patient. The value of predictive score models. , 1997, Scandinavian journal of gastroenterology.

[278]  Pirenzepine in Non-Ulcer Dyspepsia: A Double-Blind Multicentre Trial , 1990, The Journal of international medical research.