Flexible Distributed Pressure Sensing Strip for a Urethral Catheter

A multi-sensor flexible strip is developed for a urethral catheter to measure distributed pressure in a human urethra. The developed sensor strip has important clinical applications in urodynamic testing for analyzing the causes of urinary incontinence in patients. There are two major challenges in the development of the sensor. First, a highly sensitive sensor strip that is flexible enough for urethral insertion into a human body is required. Second, the sensor has to work reliably in a liquid in vivo environment in the human body. Capacitive force sensors are designed and micro-fabricated using polyimide/polydimethylsiloxane (PDMS) substrates and copper electrodes. To remove the parasitic influence of urethral tissues, which create fringe capacitance that can lead to significant errors, a reference fringe capacitance measurement sensor is incorporated on the strip. The sensing strip is embedded on a catheter and experimental in vitro evaluation is presented using a bench-top pressure chamber. The sensors on the strip are able to provide the required sensitivity and the range. Preliminary experimental results also show promise that by using measurements from the reference parasitic sensor on the strip, the influence of parasitics from human tissue on the pressure measurements can be removed.

[1]  C. Schulman,et al.  Urinary incontinence in Belgium: a population-based epidemiological survey. , 1997, European urology.

[2]  H. Bruschini,et al.  Urodynamic changes induced by the intravaginal electrode during pelvic floor electrical stimulation , 2003, Neurourology and urodynamics.

[3]  J. Bonache,et al.  Prevalence of Urinary Incontinence among Spanish Older People Living at Home , 1998, European Urology.

[4]  K. Wise,et al.  Temperature sensitivity in silicon piezoresistive pressure transducers , 1983, IEEE Transactions on Electron Devices.

[5]  P. Abrams,et al.  Good urodynamic practices: Uroflowmetry, filling cystometry, and pressure‐flow studies * * , 2002, Neurourology and urodynamics.

[6]  Barbara Sternfeld,et al.  Is Urinary Incontinence a Barrier to Exercise in Women? , 2005, Obstetrics and gynecology.

[7]  T. Wagner,et al.  Economic costs of urinary incontinence in 1995. , 1998, Urology.

[8]  Mario Di Giovanni,et al.  Flat and Corrugated Diaphragm Design Handbook , 1982 .

[9]  A. Herzog,et al.  Prevalence and Incidence of Urinary Incontinence in Community‐Dwelling Populations , 1990, Journal of the American Geriatrics Society.

[10]  A. Erdman,et al.  Flexible Tactile Sensor for Tissue Elasticity Measurements , 2009, Journal of Microelectromechanical Systems.

[11]  D. Neal,et al.  Ambulatory monitoring of bladder and detrusor pressure during natural filling. , 1989, The Journal of urology.

[12]  A. S. Sezen,et al.  An Ultraminiature MEMS Pressure Sensor With High Sensitivity for Measurement of Intramuscular Pressure (IMP) in Patients With Neuromuscular Diseases , 2009 .

[13]  Hyeun Joong Yoon,et al.  Micro devices for a cerebrospinal fluid (CSF) shunt system , 2004 .

[14]  Srinivas Tadigadapa,et al.  Piezoelectric MEMS sensors: state-of-the-art and perspectives , 2009 .

[15]  S. Kageyama,et al.  Urinary incontinence among community‐dwelling people aged 40 years or older in Japan: Prevalence, risk factors, knowledge and self‐perception , 2000, International journal of urology : official journal of the Japanese Urological Association.

[16]  Rohit Varma,et al.  Implantable micromechanical parylene-based pressure sensors for unpowered intraocular pressure sensing , 2007 .

[17]  Kari Bø,et al.  Urinary Incontinence, Pelvic Floor Dysfunction, Exercise and Sport , 2004, Sports medicine.

[18]  P. H. Powell,et al.  Urinary incontinence: prevalence and needs. , 1979, British journal of urology.

[19]  S. L. Stanton,et al.  The standardization of terminology of lower urinary tract function recommended by the international continence society , 1990, International Urogynecology Journal.

[20]  A. S. St Leger,et al.  The prevalence, severity and factors associated with urinary incontinence in a random sample of the elderly. , 1979, Age and ageing.

[21]  M B Brown,et al.  Prevalence of urinary incontinence and other urological symptoms in the noninstitutionalized elderly. , 1986, The Journal of urology.

[22]  Nader Najafi,et al.  Initial Animal Studies of a Wireless, Batteryless, MEMS Implant for Cardiovascular Applications , 2004, Biomedical microdevices.