论文信息 - Does the CAPON Gene Confer Susceptibility to Schizophrenia? - 字舞流文

Does the CAPON Gene Confer Susceptibility to Schizophrenia?

Eastwood discusses a new study in PLoS Medicine that suggests that overexpression of the CAPON gene, leading to disruption of NMDA receptor function, may be important in the etiology of severe mental illnesses.

[1] Bin Xu,et al. Increased Expression in Dorsolateral Prefrontal Cortex of CAPON in Schizophrenia and Bipolar Disorder , 2005, PLoS medicine.

[2] Lin He,et al. Association of the carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase gene with schizophrenia in the Chinese Han population. , 2005, Biochemical and biophysical research communications.

[3] N. Craddock,et al. The genetics of schizophrenia and bipolar disorder: dissecting psychosis , 2005, Journal of Medical Genetics.

[4] A. Bassett,et al. Linkage disequilibrium mapping of schizophrenia susceptibility to the CAPON region of chromosome 1q22. , 2004, American journal of human genetics.

[5] Paul J. Harrison,et al. Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence , 2005, Molecular Psychiatry.