ChroCoLoc: an application for calculating the probability of co-localization of microarray gene expression

UNLABELLED With the production of whole genome microarray chips the ability arises to investigate whether the regulation of particular groups of genes may be influenced by their chromosomal localization. Chromosome Co-Localization probability calculator (ChroCoLoc) is a publicly available web-based tool for the analysis of co-localization of co-expressed genes identified by microarray experiments. AVAILABILITY http://www.ebi.ac.uk/expressionprofiler/

[1]  F. Baas,et al.  The Human Transcriptome Map: Clustering of Highly Expressed Genes in Chromosomal Domains , 2001, Science.

[2]  T. Liesegang.  The human transcriptome map: Clustering of highly expressed genes in chromosomal domains. Caron H, ∗ van Schaik B, van der Mee M, et al. Science 2001;291:1289–1292. , 2001 .

[3]  Purvesh Khatri,et al.  Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate , 2003, Nucleic Acids Res..

[4]  Andrea Bisognin,et al.  Detection of chromosomal regions showing differential gene expression in human skeletal muscle and in alveolar rhabdomyosarcoma , 2004, BMC Bioinform..

[5]  Douglas A. Hosack,et al.  Identifying biological themes within lists of genes with EASE , 2003, Genome Biology.

[6]  Cheng-Fu Chang,et al.  Calculating the statistical significance of physical clusters of co-regulated genes in the genome: the role of chromatin in domain-wide gene regulation. , 2004, Nucleic acids research.

[7]  Christian Schwager,et al.  Embryonic Stem Cell-Like Features of Testicular Carcinoma in Situ Revealed by Genome-Wide Gene Expression Profiling , 2004, Cancer Research.

[8]  Aedín C. Culhane,et al.  Expression Profiler: next generation - an online platform for analysis of microarray data , 2004, Nucleic Acids Res..

[9]  Catherine A. Ball,et al.  Caryoscope: An Open Source Java application for viewing microarray data in a genomic context , 2004, BMC Bioinformatics.

[10]  E. Birney,et al.  EnsMart: a generic system for fast and flexible access to biological data. , 2003, Genome research.

[11]  Terrence S. Furey,et al.  Generation and annotation of the DNA sequences of human chromosomes 2 and 4 , 2005, Nature.

[12]  Benjamin Georgi,et al.  BIOINFORMATICS APPLICATIONS NOTE Gene expression MACAT—microarray chromosome analysis tool , 2022 .