Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice
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L. Zender | S. Aerts | G. Halder | T. Roskams | J. Marine | Randy L. Johnson | M. de Waegeneer | J. Jacobs | S. Verhulst | I. Mannaerts | L. V. van Grunsven | Laura Van den Mooter | Matthias Van Haele | Ruçhan Karaman | Jun Xie | W. Kowalczyk | I. Moya | Stéphanie A. Castaldo | Ana Algueró-Nadal | Panagiotis Karras | H. Hillen | S. Soheily | E. Verboven | L. van Huffel | L. Sansores-García | L. Van Huffel
[1] A. van Oudenaarden,et al. Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration. , 2019, Cell stem cell.
[2] T. Igaki,et al. Cell competition: Emerging mechanisms to eliminate neighbors , 2018, Development, growth & differentiation.
[3] T. Luedde,et al. Necroptosis microenvironment directs lineage commitment in liver cancer , 2018, Nature.
[4] G. Berx,et al. Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes. , 2017, Cell stem cell.
[5] Yasuyuki Fujita,et al. Cell competition in mammals - novel homeostatic machinery for embryonic development and cancer prevention. , 2017, Current opinion in cell biology.
[6] R. Jain,et al. YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis. , 2017, Developmental cell.
[7] J. Ajani,et al. Large tumor suppressor homologs 1 and 2 regulate mouse liver progenitor cell proliferation and maturation through antagonism of the coactivators YAP and TAZ , 2016, Hepatology.
[8] A. Bauer,et al. YAP promotes proliferation, chemoresistance, and angiogenesis in human cholangiocarcinoma through TEAD transcription factors , 2015, Hepatology.
[9] Manal M. Hassan,et al. Inactivation of Hippo Pathway Is Significantly Associated with Poor Prognosis in Hepatocellular Carcinoma , 2015, Clinical Cancer Research.
[10] Kun-Liang Guan,et al. The emerging roles of YAP and TAZ in cancer , 2015, Nature Reviews Cancer.
[11] S. O’Day,et al. Metastatic melanoma to the liver: A contemporary and comprehensive review of surgical, systemic, and regional therapeutic options , 2014, Cancer.
[12] Christof Fellmann,et al. An optimized microRNA backbone for effective single-copy RNAi. , 2013, Cell reports.
[13] G. Halder,et al. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment , 2013, Nature Reviews Drug Discovery.
[14] E. Olson,et al. Hippo pathway effector Yap promotes cardiac regeneration , 2013, Proceedings of the National Academy of Sciences.
[15] R. Wells,et al. Robust cellular reprogramming occurs spontaneously during liver regeneration. , 2013, Genes & development.
[16] David M. Thomas,et al. The Hippo pathway and human cancer , 2013, Nature Reviews Cancer.
[17] Shuji Ogino,et al. Restriction of intestinal stem cell expansion and the regenerative response by YAP , 2012, Nature.
[18] G. Gores,et al. Cholangiocarcinomas can originate from hepatocytes in mice. , 2012, The Journal of clinical investigation.
[19] S. Bicciato,et al. The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells , 2011, Cell.
[20] John McAnally,et al. Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size , 2011, Science Signaling.
[21] Dexi Liu,et al. Hydrodynamic cell delivery for simultaneous establishment of tumor growth in mouse lung, liver and kidney , 2011, Cancer biology & therapy.
[22] M. Giovannini,et al. The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals. , 2010, Developmental cell.
[23] Jiandie D. Lin,et al. TEAD mediates YAP-dependent gene induction and growth control. , 2008, Genes & development.
[24] C. Mein,et al. Yes-associated protein (YAP) functions as a tumor suppressor in breast , 2008, Cell Death and Differentiation.
[25] G. Feldmann,et al. Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals , 2007, Cell.
[26] G. Blandino,et al. The transcriptional coactivator Yes-associated protein drives p73 gene-target specificity in response to DNA Damage. , 2005, Molecular cell.
[27] L. Johnston,et al. Drosophila Myc Regulates Organ Size by Inducing Cell Competition , 2004, Cell.
[28] Konrad Basler,et al. dMyc Transforms Cells into Super-Competitors , 2004, Cell.