Association between high dietary intake of the n−3 polyunsaturated fatty acid docosahexaenoic acid and reduced risk of Crohn's disease

There are plausible mechanisms for how dietary docosahexaenoic acid (DHA), an n−3 polyunsaturated fatty acid, could prevent Crohn's disease (CD).

[1]  A. Griffiths,et al.  Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease. , 2014, The Cochrane database of systematic reviews.

[2]  W. Willett,et al.  Long-term intake of dietary fat and risk of ulcerative colitis and Crohn's disease , 2013, Gut.

[3]  K. Tsuneyama,et al.  Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet. , 2013, The Journal of toxicological sciences.

[4]  J. J. Moreno,et al.  Effect of eicosapentaenoic acid-derived prostaglandin E3 on intestinal epithelial barrier function. , 2013, Prostaglandins, leukotrienes, and essential fatty acids.

[5]  E. Riboli,et al.  Body Mass Index and the Risk for Crohn's Disease and Ulcerative Colitis: Data From a European Prospective Cohort Study (The IBD in EPIC Study) , 2013, The American Journal of Gastroenterology.

[6]  Kenneth A. Philbrick,et al.  Docosahexaenoic acid attenuates hepatic inflammation, oxidative stress, and fibrosis without decreasing hepatosteatosis in a Ldlr(-/-) mouse model of western diet-induced nonalcoholic steatohepatitis. , 2013, The Journal of nutrition.

[7]  L. Dauchet,et al.  Natural history of elderly-onset inflammatory bowel disease: a population-based cohort study , 2013, Gut.

[8]  B. Levy.  Resolvin D1 and Resolvin E1 Promote the Resolution of Allergic Airway Inflammation via Shared and Distinct Molecular Counter-Regulatory Pathways , 2012, Front. Immun..

[9]  David C. Wilson,et al.  Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease , 2012, Nature.

[10]  S. Serini,et al.  EPA and DHA differentially affect in vitro inflammatory cytokine release by peripheral blood mononuclear cells from Alzheimer's patients. , 2012, Current Alzheimer research.

[11]  Bertram Wiedenmann,et al.  Omega-3 fatty acids and their lipid mediators: towards an understanding of resolvin and protectin formation. , 2012, Prostaglandins & other lipid mediators.

[12]  E. Giovannucci,et al.  Higher predicted vitamin D status is associated with reduced risk of Crohn's disease. , 2012, Gastroenterology.

[13]  A. Ananthakrishnan.  Environmental Triggers for Inflammatory Bowel Disease , 2012, Current Gastroenterology Reports.

[14]  E. Szigethy,et al.  Inflammatory bowel disease. , 2011, Pediatric clinics of North America.

[15]  S. Shaikh,et al.  The nutritional and clinical significance of lipid rafts , 2010, Current opinion in clinical nutrition and metabolic care.

[16]  J. Mindell,et al.  National Diet and Nutrition Survey. Headline results from Year 1 of the Rolling Programme (2008/2009): Chapter 4 Physical measurements , 2010 .

[17]  E. Riboli,et al.  Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested case–control study within a European prospective cohort study , 2009, Gut.

[18]  Charles N. Serhan,et al.  Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators , 2008, Nature Reviews Immunology.

[19]  A. Cohen,et al.  Omega-3 free fatty acids for the maintenance of remission in Crohn disease: the EPIC Randomized Controlled Trials. , 2008, JAMA.

[20]  P. Palange,et al.  From the authors , 2007, European Respiratory Journal.

[21]  K. Fritsche.  Fatty acids as modulators of the immune response. , 2006, Annual review of nutrition.

[22]  Makoto Arita,et al.  Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[23]  K. Wakai,et al.  Dietary Risk Factors for Inflammatory Bowel Disease: A Multicenter Case‐Control Study in Japan , 2005, Inflammatory bowel diseases.

[24]  N. Espat,et al.  NF-κB inhibition by ω-3 fatty acids modulates LPS-stimulated macrophage TNF-α transcription , 2003 .

[25]  N. Espat,et al.  NF-kappa B inhibition by omega -3 fatty acids modulates LPS-stimulated macrophage TNF-alpha transcription. , 2003, American journal of physiology. Lung cellular and molecular physiology.

[26]  N E Day,et al.  European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection , 2002, Public Health Nutrition.

[27]  S. Wootton,et al.  Eicosapentaenoic and docosapentaenoic acids are the principal products of α-linolenic acid metabolism in young men* , 2002, British Journal of Nutrition.

[28]  E. Cabré,et al.  Effect of olive oil on early and late events of colon carcinogenesis in rats: modulation of arachidonic acid metabolism and local prostaglandin E2 synthesis , 2000, Gut.

[29]  J. Hibbeln,et al.  In vivo conversion of linoleic acid to arachidonic acid in human adults. , 1999, Prostaglandins, leukotrienes, and essential fatty acids.

[30]  V. Todorović,et al.  [Platelet function]. , 1998, Srpski arhiv za celokupno lekarstvo.

[31]  N Slimani,et al.  Pilot phase studies on the accuracy of dietary intake measurements in the EPIC project: overall evaluation of results. European Prospective Investigation into Cancer and Nutrition. , 1997, International journal of epidemiology.

[32]  N E Day,et al.  Validation of dietary assessment methods in the UK arm of EPIC using weighed records, and 24-hour urinary nitrogen and potassium and serum vitamin C and carotenoids as biomarkers. , 1997, International journal of epidemiology.

[33]  J. Lennard-jones,et al.  Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD). , 1996, Gut.

[34]  M. Campieri,et al.  Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease. , 1996, The New England journal of medicine.

[35]  Deventer,et al.  Soluble Fc gamma receptor III (CD 16) and eicosanoid concentrations in gut lavage fluid from patients with inflammatory bowel disease: reflection of mucosal inflammation. , 1996, Gut.

[36]  R A Goldbohm,et al.  Reproducibility of a food frequency questionnaire and stability of dietary habits determined from five annually repeated measurements. , 1995, European journal of clinical nutrition.

[37]  S. Dahlén,et al.  Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. , 1987, Science.

[38]  J. White,et al.  Effect of docosahexaenoic acid (DHA) on arachidonic acid metabolism and platelet function. , 1983, Biochemical and biophysical research communications.

[39]  E. Goetzl,et al.  Human neutrophil chemotactic and degranulating activities of leukotriene B5 (LTB5) derived from eicosapentaenoic acid. , 1983, Biochemical and biophysical research communications.

[40]  E. Corey,et al.  Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene biosynthesis. , 1983, Proceedings of the National Academy of Sciences of the United States of America.