Ovine multiparity is associated with diminished vaginal muscularis, increased elastic fibres and vaginal wall weakness: implication for pelvic organ prolapse

[1]  J. Werkmeister,et al.  Vaginal wall weakness in parous ewes: a potential preclinical model of pelvic organ prolapse , 2017, International Urogynecology Journal.

[2]  Anthony W. Papageorgiou,et al.  Real-time measurement of the vaginal pressure profile using an optical-fiber-based instrumented speculum , 2016, Journal of biomedical optics.

[3]  J. Werkmeister,et al.  Tissue response to collagen containing polypropylene meshes in an ovine vaginal repair model. , 2016, Acta biomaterialia.

[4]  J. Werkmeister,et al.  Identification and Characterization of Human Endometrial Mesenchymal Stem/Stromal Cells and Their Potential for Cellular Therapy , 2016, Stem cells translational medicine.

[5]  C. Gargett,et al.  Endometrial mesenchymal stem cells as a cell based therapy for pelvic organ prolapse. , 2016, World journal of stem cells.

[6]  S. Abramowitch,et al.  Impact of parity on ewe vaginal mechanical properties relative to the nonhuman primate and rodent , 2016, International Urogynecology Journal.

[7]  J. Werkmeister,et al.  Changes in pelvic organ prolapse mesh mechanical properties following implantation in rats. , 2016, American journal of obstetrics and gynecology.

[8]  K. Kluivers,et al.  Risk factors for pelvic organ prolapse and its recurrence: a systematic review , 2015, International Urogynecology Journal.

[9]  J. Werkmeister,et al.  Regional Variation in Tissue Composition and Biomechanical Properties of Postmenopausal Ovine and Human Vagina , 2014, PloS one.

[10]  S. Lye,et al.  Expression of Extracellular Matrix-Remodeling Proteins Is Altered in Vaginal Tissue of Premenopausal Women With Severe Pelvic Organ Prolapse , 2014, Reproductive Sciences.

[11]  J. Werkmeister,et al.  Influence of Reproductive Status on Tissue Composition and Biomechanical Properties of Ovine Vagina , 2014, PloS one.

[12]  J. Ashton-Miller,et al.  Relationship between intra-abdominal pressure and vaginal wall movements during Valsalva in women with and without pelvic organ prolapse: technique development and early observations , 2014, International Urogynecology Journal.

[13]  C. Maher,et al.  Epidemiology and outcome assessment of pelvic organ prolapse , 2013, International Urogynecology Journal.

[14]  A. Feola,et al.  Deterioration in biomechanical properties of the vagina following implantation of a high‐stiffness prolapse mesh , 2013, BJOG : an international journal of obstetrics and gynaecology.

[15]  I. Milsom,et al.  Prevalence and risk factors for pelvic organ prolapse 20 years after childbirth: a national cohort study in singleton primiparae after vaginal or caesarean delivery , 2013, BJOG : an international journal of obstetrics and gynaecology.

[16]  Antonio J. M. Ferreira,et al.  Biomechanical Properties of Vaginal Tissue in Women with Pelvic Organ Prolapse , 2012, Gynecologic and Obstetric Investigation.

[17]  J. Werkmeister,et al.  A Preclinical Evaluation of Alternative Synthetic Biomaterials for Fascial Defect Repair Using a Rat Abdominal Hernia Model , 2012, PloS one.

[18]  A. Lenis,et al.  Animal models of female pelvic organ prolapse: lessons learned. , 2012, Expert review of obstetrics & gynecology.

[19]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[20]  Madhusudhan Budatha,et al.  Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans. , 2011, The Journal of clinical investigation.

[21]  P. Geavlete,et al.  Pelvic Organ Prolapse Quantification System (POP–Q) – a new era in pelvic prolapse staging , 2011, Journal of medicine and life.

[22]  Steven Abramowitch,et al.  Parity negatively impacts vaginal mechanical properties and collagen structure in rhesus macaques. , 2010, American journal of obstetrics and gynecology.

[23]  L. Meyn,et al.  Alteration of Vaginal Elastin Metabolism in Women With Pelvic Organ Prolapse , 2010, Obstetrics and gynecology.

[24]  P. Zimmern,et al.  Extracellular matrix expression of human prolapsed vaginal wall , 2010, Neurourology and urodynamics.

[25]  R. Negro,et al.  Age-related pelvic floor modifications and prolapse risk factors in postmenopausal women , 2010, Menopause.

[26]  M. Damaser,et al.  The Impact of Cesarean Delivery on Pelvic Floor Dysfunction in Lysyl Oxidase Like-1 Knockout Mice , 2010, Female pelvic medicine & reconstructive surgery.

[27]  Ling Ouyang,et al.  [Expression and significance of elastin and fibulin-5 in anterior vaginal tissue of women with pelvic organ prolapse]. , 2009, Zhonghua fu chan ke za zhi.

[28]  M. Eijkemans,et al.  The prevalence of pelvic organ prolapse symptoms and signs and their relation with bladder and bowel disorders in a general female population , 2009, International Urogynecology Journal.

[29]  H. Taylor,et al.  Diminished vaginal HOXA13 expression in women with pelvic organ prolapse , 2009, Menopause.

[30]  Jennifer M Wu,et al.  Prevalence of symptomatic pelvic floor disorders in US women. , 2008, JAMA.

[31]  K. Candiotti,et al.  Vaginal smooth muscle cell apoptosis is increased in women with pelvic organ prolapse , 2008, International Urogynecology Journal.

[32]  A. Markland,et al.  Prolapse and incontinence surgery in older women. , 2008, The Journal of urology.

[33]  H. Tibbals,et al.  Biomechanical properties of the vaginal wall: effect of pregnancy, elastic fiber deficiency, and pelvic organ prolapse. , 2008, American journal of obstetrics and gynecology.

[34]  P. Bousquet,et al.  Comparative histological analysis of anterior vaginal wall in women with pelvic organ prolapse or control subjects. A pilot study , 2008, International Urogynecology Journal.

[35]  Renaud de Tayrac,et al.  Collagen-coated vs noncoated low-weight polypropylene meshes in a sheep model for vaginal surgery. A pilot study , 2007, International Urogynecology Journal.

[36]  I. Diez-Itza,et al.  Risk factors for the recurrence of pelvic organ prolapse after vaginal surgery: a review at 5 years after surgery , 2007, International Urogynecology Journal.

[37]  K. Csiszȧr,et al.  Pelvic organ prolapse in fibulin-5 knockout mice: pregnancy-induced changes in elastic fiber homeostasis in mouse vagina. , 2007, The American journal of pathology.

[38]  P. Moalli,et al.  Remodeling of vaginal connective tissue in patients with prolapse , 2006, Obstetrics and gynecology.

[39]  J. Deprest,et al.  The biology behind fascial defects and the use of implants in pelvic organ prolapse repair , 2006, International Urogynecology Journal.

[40]  L. Meyn,et al.  Remodeling of Vaginal Connective Tissue in Patients With Prolapse , 2005, Current opinion in obstetrics & gynecology.

[41]  O. Nyrén,et al.  Prevalence of symptomatic pelvic organ prolapse in a Swedish population , 2005, International Urogynecology Journal.

[42]  John O L DeLancey,et al.  The hidden epidemic of pelvic floor dysfunction: achievable goals for improved prevention and treatment. , 2005, American journal of obstetrics and gynecology.

[43]  M. Collins,et al.  Aspartic acid racemization: evidence for marked longevity of elastin in human skin , 2003, The British journal of dermatology.

[44]  J. Schaffer,et al.  Morphometric properties of the posterior vaginal wall in women with pelvic organ prolapse. , 2002, American journal of obstetrics and gynecology.

[45]  J. Schaffer,et al.  Morphometric analysis of smooth muscle in the anterior vaginal wall of women with pelvic organ prolapse. , 2002, American journal of obstetrics and gynecology.

[46]  J. Delancey,et al.  Pelvic organ prolapse in young women , 1997, Obstetrics and gynecology.

[47]  J. Colling,et al.  Epidemiology of Surgically Managed Pelvic Organ Prolapse and Urinary Incontinence , 1997, Obstetrics and gynecology.

[48]  L. Brubaker,et al.  The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. , 1996, American journal of obstetrics and gynecology.

[49]  James B. Brown,et al.  THE AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY , 1991 .

[50]  R. Zacharin,et al.  Genital Prolapse in Ruminants , 1969, The Australian & New Zealand journal of obstetrics & gynaecology.

[51]  B. Fischer.  Lessons Learned. , 2016, Schizophrenia bulletin.