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[1]  L. Fritts,et al.  Limited dissemination of pathogenic SIV after vaginal challenge of rhesus monkeys immunized with a live, attenuated lentivirus. , 2009, Virology.

[2]  C. Rouzioux,et al.  Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses1 , 2009, The Journal of Immunology.

[3]  Austin Hughes,et al.  Ultradeep Pyrosequencing Detects Complex Patterns of CD8+ T-Lymphocyte Escape in Simian Immunodeficiency Virus-Infected Macaques , 2009, Journal of Virology.

[4]  D. H. Young,et al.  Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control. , 2009, Blood.

[5]  L. Picker,et al.  Effector-memory T cell responses are associated with protection of rhesus monkeys from mucosal SIV challenge , 2009, Nature Medicine.

[6]  M. McChesney,et al.  Antiviral CD8+ T cells in the genital tract control viral replication and delay progression to AIDS after vaginal SIV challenge in rhesus macaques immunized with virulence attenuated SHIV 89.6 , 2009, Journal of internal medicine.

[7]  O. Yang.  Assessing the antiviral activity of HIV-1-specific cytotoxic T lymphocytes. , 2009, Methods in molecular biology.

[8]  D. Burton,et al.  Macaques vaccinated with live-attenuated SIV control replication of heterologous virus , 2008, The Journal of experimental medicine.

[9]  D. Lu,et al.  With Minimal Systemic T-Cell Expansion, CD8+ T Cells Mediate Protection of Rhesus Macaques Immunized with Attenuated Simian-Human Immunodeficiency Virus SHIV89.6 from Vaginal Challenge with Simian Immunodeficiency Virus , 2008, Journal of Virology.

[10]  J. Lifson,et al.  Antiretroviral Therapy prior to Acute Viral Replication Preserves CD4 T Cells in the Periphery but Not in Rectal Mucosa during Acute Simian Immunodeficiency Virus Infection , 2008, Journal of Virology.

[11]  R. Stebbings,et al.  Resistance to superinfection by a vigorously replicating, uncloned stock of simian immunodeficiency virus (SIVmac251) stimulates replication of a live attenuated virus vaccine (SIVmacC8). , 2008, The Journal of general virology.

[12]  A. Haase,et al.  Protective attenuated lentivirus immunization induces SIV-specific T cells in the genital tract of rhesus monkeys , 2008, Mucosal Immunology.

[13]  R. Sékaly.  The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development? , 2008, The Journal of experimental medicine.

[14]  D. Douek,et al.  High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage , 2008, Mucosal Immunology.

[15]  D. Watkins,et al.  Recognition of Escape Variants in ELISPOT Does Not Always Predict CD8+ T-Cell Recognition of Simian Immunodeficiency Virus-Infected Cells Expressing the Same Variant Sequences , 2007, Journal of Virology.

[16]  Z. Grossman,et al.  Progressive CD4+ central–memory T cell decline results in CD4+ effector–memory insufficiency and overt disease in chronic SIV infection , 2007, The Journal of experimental medicine.

[17]  T. Matano,et al.  Induction of CD8+ Cells Able To Suppress CCR5-Tropic Simian Immunodeficiency Virus SIVmac239 Replication by Controlled Infection of CXCR4-Tropic Simian-Human Immunodeficiency Virus in Vaccinated Rhesus Macaques , 2007, Journal of Virology.

[18]  D. Watkins,et al.  Gag-Specific CD8+ T Lymphocytes Recognize Infected Cells before AIDS-Virus Integration and Viral Protein Expression1 , 2007, The Journal of Immunology.

[19]  D. Watkins,et al.  The Antiviral Efficacy of Simian Immunodeficiency Virus-Specific CD8+ T Cells Is Unrelated to Epitope Specificity and Is Abrogated by Viral Escape , 2006, Journal of Virology.

[20]  D. Watkins,et al.  Not All Cytokine-Producing CD8+ T Cells Suppress Simian Immunodeficiency Virus Replication , 2006, Journal of Virology.

[21]  D. O’Connor,et al.  Simian Immunodeficiency Virus SIVmac239 Infection of Major Histocompatibility Complex-Identical Cynomolgus Macaques from Mauritius , 2006, Journal of Virology.

[22]  V. Maino,et al.  IL-15 induces CD4 effector memory T cell production and tissue emigration in nonhuman primates. , 2006, The Journal of clinical investigation.

[23]  R. Le Grand,et al.  Changes in Soluble Factor-Mediated CD8+ Cell-Derived Antiviral Activity in Cynomolgus Macaques Infected with Simian Immunodeficiency Virus SIVmac251: Relationship to Biological Markers of Progression , 2006, Journal of Virology.

[24]  D. Watkins,et al.  Tat28-35SL8-Specific CD8+ T Lymphocytes Are More Effective than Gag181-189CM9-Specific CD8+ T Lymphocytes at Suppressing Simian Immunodeficiency Virus Replication in a Functional In Vitro Assay , 2005, Journal of Virology.

[25]  G. Hale,et al.  CD8+ Lymphocytes Do Not Mediate Protection against Acute Superinfection 20 Days after Vaccination with a Live Attenuated Simian Immunodeficiency Virus , 2005, Journal of Virology.

[26]  Qingsheng Li,et al.  Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells , 2005, Nature.

[27]  Mario Roederer,et al.  Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection , 2005, Nature.

[28]  O. Yang,et al.  Parallel Human Immunodeficiency Virus Type 1-Specific CD8+ T-Lymphocyte Responses in Blood and Mucosa during Chronic Infection , 2005, Journal of Virology.

[29]  Philip R. Johnson,et al.  HIV vaccine design: insights from live attenuated SIV vaccines , 2005, Nature Immunology.

[30]  A. Wade-Evans,et al.  Vaccination with live attenuated simian immunodeficiency virus for 21 days protects against superinfection. , 2004, Virology.

[31]  V. Maino,et al.  Insufficient Production and Tissue Delivery of CD4+Memory T Cells in Rapidly Progressive Simian Immunodeficiency Virus Infection , 2004, The Journal of experimental medicine.

[32]  Wayne C Koff,et al.  HIV vaccine design and the neutralizing antibody problem , 2004, Nature Immunology.

[33]  Julie Elliott,et al.  Optimization of methods to assess human mucosal T-cell responses to HIV infection. , 2003, Journal of immunological methods.

[34]  D. Nixon,et al.  Trafficking of Human Immunodeficiency Virus Type 1-Specific CD8+ T Cells to Gut-Associated Lymphoid Tissue during Chronic Infection , 2003, Journal of Virology.

[35]  M. McElrath,et al.  Ontogeny and Specificities of Mucosal and Blood Human Immunodeficiency Virus Type 1-Specific CD8+ Cytotoxic T Lymphocytes , 2003, Journal of Virology.

[36]  A. Wade-Evans,et al.  Mechanisms of protection induced by attenuated simian immunodeficiency virus. , 2002, Virology.

[37]  R. Johnson,et al.  Mechanisms of protection against simian immunodeficiency virus infection. , 2002, Vaccine.

[38]  K. Mansfield,et al.  Simian immunodeficiency virus (SIV)-specific cytotoxic T lymphocytes in gastrointestinal tissues of chronically SIV-infected rhesus monkeys. , 2001, Blood.

[39]  A. Wade-Evans,et al.  Mechanisms of protection induced by live attenuated simian immunodeficiency virus , 2001, Journal of medical primatology.

[40]  Todd M. Allen,et al.  Induction of Mucosal Homing Virus-Specific CD8+ T Lymphocytes by Attenuated Simian Immunodeficiency Virus , 2000, Journal of Virology.

[41]  D. Montefiori,et al.  Protection by Live, Attenuated Simian Immunodeficiency Virus against Heterologous Challenge , 1999, Journal of Virology.

[42]  D. Montefiori,et al.  Highly Attenuated Vaccine Strains of Simian Immunodeficiency Virus Protect against Vaginal Challenge: Inverse Relationship of Degree of Protection with Level of Attenuation , 1999, Journal of Virology.

[43]  L. Cioé,et al.  Long-lasting protection by live attenuated simian immunodeficiency virus in cynomolgus monkeys: no detection of reactivation after stimulation with a recall antigen. , 1999, Virology.

[44]  D. Ho,et al.  Temporal Analyses of Virus Replication, Immune Responses, and Efficacy in Rhesus Macaques Immunized with a Live, Attenuated Simian Immunodeficiency Virus Vaccine , 1998, Journal of Virology.

[45]  S. Cobbold,et al.  Mechanisms of protection induced by attenuated simian immunodeficiency virus. II. Lymphocyte depletion does not abrogate protection. , 1998, AIDS research and human retroviruses.

[46]  R. Means,et al.  Inhibition of Simian Immunodeficiency Virus (SIV) Replication by CD8+ T Lymphocytes from Macaques Immunized with Live Attenuated SIV , 1998, Journal of Virology.

[47]  R. Desrosiers,et al.  Protective immunity induced by live attenuated simian immunodeficiency virus. , 1998, Current opinion in immunology.

[48]  L. Chieco‐Bianchi,et al.  Live attenuated simian immunodeficiency virus prevents super-infection by cloned SIVmac251 in cynomolgus monkeys. , 1997, The Journal of general virology.

[49]  R. Stebbings,et al.  Mechanisms of protection induced by attenuated simian immunodeficiency virus. I. Protection cannot be transferred with immune serum. , 1997, The Journal of general virology.

[50]  R P Johnson,et al.  Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms , 1997, Journal of virology.

[51]  N. Almond,et al.  Protection by attenuated simian immunodeficiency virus in macaques against challenge with virus-infected cells , 1995, The Lancet.

[52]  R. Desrosiers,et al.  Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene. , 1992, Science.

[53]  R. Desrosiers,et al.  Importance of the nef gene for maintenance of high virus loads and for development of AIDS , 1991, Cell.

[54]  R. Desrosiers,et al.  Comparison of simian immunodeficiency virus isolates , 1988, Nature.