Elective stenting of extracranial carotid arteries.

OBJECTIVES In symptomatic and asymptomatic patients with significant carotid artery stenosis, surgical endarterectomy has been shown to be beneficial when compared with medical management. Carotid stenting is evolving as an alternative technique for treating such patients. This prospective study was designed to assess the feasibility and safety of carotid angioplasty and stenting. METHODS Fourteen patients (15 carotid arteries) with significant carotid artery stenosis were enrolled. These patients were in the age range 46 to 84 years (mean 60.9 +/- 7 years) and there were 12 males (86%). All of these patients were symptomatic with either TIA (n = 8) or stroke (n = 6). Wallstents were used in all the cases to stent the carotid arteries. One patient underwent bilateral carotid artery stenting. RESULTS Carotid angioplasty and stenting was successful in 13 out of 14 (92.8%) patients and 14 out of 15 (93.3%) carotid arteries, with reduction in mean (+/- SD) stenosis from 86 +/- 6% to 3 +/- 3%. There was one episode of minor stroke, no major stroke or death during the initial hospitalization. Another patient had a minor stroke with patent ipsilateral carotid artery (on repeat angiography) during the first 30 days after the procedure. This patient was also found to have asymptomatic thrombus formation in the contralateral carotid stent which resolved with intravenous anticoagulation. During a mean follow up of 6 +/- 2 months there has been no recurrence of symptoms. CONCLUSIONS Based upon our limited experience we believe that percutaneous carotid angioplasty with stenting is feasible with low periprocedural complication rate.

[1]  D. Sackett,et al.  Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis. , 1991, The New England journal of medicine.

[2]  W. Edwards,et al.  Recurrent carotid artery stenosis. Resection with autogenous vein replacement. , 1989, Annals of surgery.

[3]  L. Wilkins North American Symptomatic Carotid Endarterectomy Trial. Methods, patient characteristics, and progress. , 1991, Stroke.

[4]  P. Courtheoux,et al.  New triple coaxial catheter system for carotid angioplasty with cerebral protection. , 1990, AJNR. American journal of neuroradiology.

[5]  Lippincott Williams Wilkins,et al.  Study design for randomized prospective trial of carotid endarterectomy for asymptomatic atherosclerosis. The Asymptomatic Carotid Atherosclerosis Study Group. , 1989, Stroke.

[6]  S. Rahimtoola,et al.  The hibernating myocardium. , 1989, American heart journal.

[7]  D. E. Strandness,et al.  Carotid artery stenosis following endarterectomy. , 1982, Archives of surgery.

[8]  A. Davies,et al.  Endarterectomy for asymptomatic carotid artery stenosis , 1995, BMJ.

[9]  R. Brook,et al.  The appropriateness of carotid endarterectomy. , 1988, The New England journal of medicine.

[10]  P. Heinrich,et al.  Transluminal angioplasty for the treatment of carotid artery stenoses. , 1987, VASA. Zeitschrift fur Gefasskrankheiten.

[11]  R. Higashida,et al.  Practical aspects of percutaneous transluminal angioplasty of the carotid artery. , 1986, Acta radiologica. Supplementum.

[12]  J. Marler,et al.  Measurements of acute cerebral infarction: a clinical examination scale. , 1989, Stroke.

[13]  R. Lusby,et al.  Complications of carotid endarterectomy. , 1983, The Surgical clinics of North America.