Charting the progression in semantic dementia: implications for the organisation of semantic memory.

Abstract A patient, JL, with the syndrome of semantic dementia was assessed longitudinally over a two-year period. The data presented here address the controversy concerning the hierarchical organisation of semantic memory. On a range of category fluency tests, when first tested JL was just within the normal range on the broadest categories of animals and household items, but was virtually unable to produce any instances of specific categories such as breeds of dog or musical instruments. Longitudinal fluency data for the animal category demonstrate that while JL continued to produce the most prototypical responses (cat, dog, horse), other animal labels dropped out early from his vocabulary. On the picture-sorting tests from our semantic memory test battery, JL's discrimination between living things and man-made objects was preserved for a substantial time in conjunction with a marked decline in his sorting ability for more specific categories, particularly features or attributes (e.g. size, foreign-ness,...

[1]  D. Wechsler.  A Standardized Memory Scale for Clinical Use , 1945 .

[2]  R. C. Oldfield,et al.  Object-naming by Dysphasic Patients , 1965, Nature.

[3]  G. Rochford,et al.  Studies in the development and breakdown of the use of names. IV. The effects of word frequency. , 1965, Journal of neurology, neurosurgery, and psychiatry.

[4]  M. Ross Quillian,et al.  Retrieval time from semantic memory , 1969 .

[5]  E. Kaplan,et al.  The assessment of aphasia and related disorders , 1972 .

[6]  E. Tulving,et al.  Episodic and semantic memory , 1972 .

[7]  E. Warrington.  Quarterly Journal of Experimental Psychology the Selective Impairment of Semantic Memory the Selective Impairment of Semantic Memory , 2022 .

[8]  M. Schwartz,et al.  Dissociations of language function in dementia: A case study , 1979, Brain and Language.

[9]  J. G. Snodgrass,et al.  A standardized set of 260 pictures: norms for name agreement, image agreement, familiarity, and visual complexity. , 1980, Journal of experimental psychology. Human learning and memory.

[10]  M. Mesulam,et al.  Slowly progressive aphasia without generalized dementia , 1982, Annals of neurology.

[11]  Rosaleen A. McCarthy,et al.  Reading without Semantics , 1983 .

[12]  E. Warrington,et al.  CATEGORY SPECIFIC ACCESS DYSPHASIA , 1983 .

[13]  E. Tulving.  Elements of episodic memory , 1983 .

[14]  R. Nass,et al.  The assessment of aphasia and related disorders By Harold Goodglass and edith kaplan philadelphia, lea & febiger, 1983 illustrated, $27.50 (package) , 1984 .

[15]  T. Shallice,et al.  Category specific semantic impairments , 1984 .

[16]  James L. McClelland,et al.  Distributed memory and the representation of general and specific information. , 1985, Journal of experimental psychology. General.

[17]  E. Warrington,et al.  Phonological Reading: Phenomena and Paradoxes , 1986, Cortex.

[18]  T. Chang.  Semantic memory: Facts and models. , 1986 .

[19]  G. Humphreys,et al.  Visual object processing in optic aphasia: a case of semantic access agnosia , 1987 .

[20]  Mario Liotti,et al.  Semantic Amnesia with Preservation of Autobiographic Memory. A Case Report , 1987, Cortex.

[21]  G. Humphreys,et al.  The Fractionation of Visual Agnosia , 1987 .

[22]  E Capitani,et al.  Progressive language impairment without dementia: a case with isolated category specific semantic defect. , 1988, Journal of neurology, neurosurgery, and psychiatry.

[23]  T. Shallice.  From Neuropsychology to Mental Structure: Converging Operations: Specific Syndromes and Evidence from Normal Subjects , 1988 .

[24]  Giuseppe Sartori,et al.  The oyster with four legs: A neuropsychological study on the interaction of visual and semantic information , 1998 .

[25]  Glyn W. Humphreys,et al.  Cascade processes in picture identification , 1988 .

[26]  C. Luzzatti,et al.  Slowly progressive aphasia in three patients. The problem of accompanying neuropsychological deficit. , 1988, Brain : a journal of neurology.

[27]  E. Warrington,et al.  Evidence for modality-specific meaning systems in the brain , 1988, Nature.

[28]  V. Pietrini,et al.  Recovery from herpes simplex encephalitis: selective impairment of specific semantic categories with neuroradiological correlation. , 1988, Journal of neurology, neurosurgery, and psychiatry.

[29]  A. Caramazza,et al.  General to specific access to word meaning: A claim re-examined , 1989 .

[30]  D. Neary,et al.  Semantic dementia: a form of circumscribed cerebral atrophy , 1995 .

[31]  M N Rossor,et al.  Heterogeneity in progressive aphasia due to focal cortical atrophy. A clinical and PET study. , 1990, Brain : a journal of neurology.

[32]  Alfonso Caramazza,et al.  Selective impairment of semantics in lexical processing , 1990 .

[33]  Alfonso Caramazza,et al.  The multiple semantics hypothesis: Multiple confusions? , 1990 .

[34]  E. Wolters,et al.  [Slowly progressive aphasia without dementia]. , 1991, Nederlands tijdschrift voor geneeskunde.

[35]  Alfonso Caramazza,et al.  Mechanisms for accessing lexical representations for output: Evidence from a category-specific semantic deficit , 1991, Brain and Language.

[36]  D. Salmon,et al.  The nature of the naming deficit in Alzheimer's and Huntington's disease. , 1991, Brain : a journal of neurology.

[37]  A. Caramazza,et al.  Category-specific naming and comprehension impairment: a double dissociation. , 1991, Brain : a journal of neurology.

[38]  J. Hodges,et al.  Deterioration of word meaning: Implications for reading , 1992, Neuropsychologia.

[39]  D. Salmon,et al.  Semantic memory impairment in Alzheimer's disease: Failure of access or degraded knowledge? , 1992, Neuropsychologia.

[40]  M. Behrmann,et al.  Surface dyslexia and dysgraphia: dual routes, single lexicon , 1992 .

[41]  David Caplan,et al.  Constraining theories of semantic memory processing: Evidence from Dementia , 1992 .

[42]  J. Hodges,et al.  Semantic dementia. Progressive fluent aphasia with temporal lobe atrophy. , 1992 .

[43]  A. Caramazza,et al.  On the distinction between deficits of access and deficits of storage : a question of theory , 1993 .

[44]  Glyn W. Humphreys,et al.  A verbal-semantic category-specific recognition impairment , 1993 .

[45]  A. Parkin,et al.  Progressive Aphasia without Dementia: A Clinical and Cognitive Neuropsychological Analysis , 1993, Brain and Language.

[46]  Myrna F. Schwartz,et al.  Of cabbages and things: Semantic memory from a neuropsychological perspective—A tutorial review. , 1994 .

[47]  Lorraine K. Tyler,et al.  Loss of Semantic Memory: Implications for the Modularity of Mind , 1994 .

[48]  J. Hodges,et al.  The relationship between comprehension and oral reading in progressive fluent aphasia , 1994, Neuropsychologia.

[49]  E. Funnell.  Objects and properties: a study of the breakdown of semantic memory. , 1995, Memory.

[50]  J. Hodges,et al.  Is semantic memory consistently impaired early in the course of Alzheimer's disease? Neuroanatomical and diagnostic implications , 1995, Neuropsychologia.

[51]  J. Greene.  Contributions to Neuropsychological Assessment , 1995 .

[52]  M J Farah,et al.  Preservation of categorical knowledge in Alzheimer's disease: a computational account. , 1995, Memory.

[53]  J. Hodges,et al.  Disorders of semantic memory. , 1997, Journal of neurology, neurosurgery, and psychiatry.