Prophylactic administration of abatacept prevents disease and bone destruction in a rat model of collagen-induced arthritis.

[1]  P. Lipsky,et al.  The role of the T cell in autoimmune inflammation , 2005, Arthritis research & therapy.

[2]  M. Dougados,et al.  Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig. , 2003, The New England journal of medicine.

[3]  J. Smolen,et al.  Therapeutic strategies for rheumatoid arthritis , 2003, Nature Reviews Drug Discovery.

[4]  R. Hoffman.  T cells in the pathogenesis of systemic lupus erythematosus. , 2001, Clinical immunology.

[5]  N. Williams,et al.  The genetic and immunopathological processes underlying collagen‐induced arthritis , 2001, Immunology.

[6]  G. Panayi,et al.  Cytokine pathways and joint inflammation in rheumatoid arthritis. , 2001, The New England journal of medicine.

[7]  K. Hathcock,et al.  Blockade of Costimulation Through B7/CD28 Inhibits Experimental Autoimmune Uveoretinitis, But Does Not Induce Long-Term Tolerance , 2000, The Journal of Immunology.

[8]  S. Goldring,et al.  Pathogenesis of bone erosions in rheumatoid arthritis , 2000, Current opinion in rheumatology.

[9]  J. Bluestone,et al.  A Critical Role for B7/CD28 Costimulation in Experimental Autoimmune Encephalomyelitis: A Comparative Study Using Costimulatory Molecule-Deficient Mice and Monoclonal Antibody Blockade1 , 2000, The Journal of Immunology.

[10]  M. Feldmann,et al.  Prevention and amelioration of collagen‐induced arthritis by blockade of the CD28 co‐stimulatory pathway: requirement for both B7‐1 and B7‐2 , 1996, European journal of immunology.

[11]  J. Bluestone,et al.  CD28/B7 system of T cell costimulation. , 1996, Annual review of immunology.

[12]  R. Karr,et al.  Collagen-induced arthritis in the BB rat. Prevention of disease by treatment with CTLA-4-Ig. , 1995, The Journal of clinical investigation.

[13]  R. Karr,et al.  Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation. , 1995, The Journal of clinical investigation.

[14]  P. Albert,et al.  Role of B7:CD28/CTLA-4 in the induction of chronic relapsing experimental allergic encephalomyelitis. , 1995, Journal of immunology.

[15]  P. Linsley,et al.  Treatment of murine lupus with CTLA4Ig. , 1994, Science.

[16]  J. Seyer,et al.  T cell epitopes of type II collagen that regulate murine collagen-induced arthritis. , 1993, Journal of immunology.

[17]  Wooley Ph,et al.  Immunogenetics of collagen-induced arthritis. , 1987 .