REST-DRD2 mechanism impacts glioblastoma stem cell-mediated tumorigenesis.
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G. Fuller | C. Coarfa | V. Baladandayuthapani | G. Rao | B. Liu | J. Gumin | F. Lang | Bethany L. Veo | A. Paulucci-Holthauzen | S. Majumder | K. Irshad | A. Marisetty | Yun-Yuh Lu | Li Lu | V. Henry | D. Kassem | Mohamed M. Kamal | Anantha L. Marisetty
[1] G. Fuller,et al. REST overexpression in mice causes deficits in spontaneous locomotion , 2018, Scientific Reports.
[2] R. Zukin,et al. REST, a master transcriptional regulator in neurodegenerative disease , 2018, Current Opinion in Neurobiology.
[3] M. Weller,et al. Vaccine-based immunotherapeutic approaches to gliomas and beyond , 2017, Nature Reviews Neurology.
[4] C. Coarfa,et al. REST represses miR-124 and miR-203 to regulate distinct oncogenic properties of glioblastoma stem cells , 2016, Neuro-oncology.
[5] E. Chiocca,et al. Glioma and microglia, a double entendre , 2016, Nature Immunology.
[6] P. Tong,et al. An expression based REST signature predicts patient survival and therapeutic response for glioblastoma multiforme , 2016, Scientific Reports.
[7] Y. Nie,et al. Dopamine D2 receptor suppresses gastric cancer cell invasion and migration via inhibition of EGFR/AKT/MMP-13 pathway. , 2016, International immunopharmacology.
[8] G. Reifenberger,et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary , 2016, Acta Neuropathologica.
[9] L. Marchionni,et al. Alterations in cellular metabolome after pharmacological inhibition of Notch in glioblastoma cells , 2016, International journal of cancer.
[10] Patrick Y. Wen,et al. Neuro-oncology in 2015: Progress in glioma diagnosis, classification and treatment , 2016, Nature Reviews Neurology.
[11] W. Wurst,et al. The REST remodeling complex protects genomic integrity during embryonic neurogenesis , 2016, eLife.
[12] K. Aldape,et al. Mir-21–Sox2 Axis Delineates Glioblastoma Subtypes with Prognostic Impact , 2015, The Journal of Neuroscience.
[13] J. Meldolesi,et al. The Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases,, , 2015, eNeuro.
[14] J. Rich,et al. Cancer stem cells in glioblastoma , 2015, Genes & development.
[15] P. Pandolfi,et al. TSPYL2 is an essential component of the REST/NRSF transcriptional complex for TGFβ signaling activation , 2015, Cell Death and Differentiation.
[16] William A. Flavahan,et al. Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells , 2014, Glia.
[17] W. Cavenee,et al. Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma , 2014, Oncotarget.
[18] D. Haussler,et al. The Somatic Genomic Landscape of Glioblastoma , 2013, Cell.
[19] E. Cattaneo,et al. Binding of the repressor complex REST‐mSIN3b by small molecules restores neuronal gene transcription in Huntington's disease models , 2013, Journal of neurochemistry.
[20] A. Roopra,et al. A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive disease , 2012, BMC Genomics.
[21] R. Dingledine,et al. Epigenetics and epilepsy , 2012, Epilepsia.
[22] Y. Ishikawa-Brush,et al. Effects on promoter activity of common SNPs in 5′ region of GABRB3 exon 1A , 2012, Epilepsia.
[23] T. MacDonald,et al. REST Is a Novel Prognostic Factor and Therapeutic Target for Medulloblastoma , 2012, Molecular Cancer Therapeutics.
[24] Tzong-Shiue Yu,et al. A restricted cell population propagates glioblastoma growth following chemotherapy , 2012, Nature.
[25] F. Zunino,et al. REST Controls Self-Renewal and Tumorigenic Competence of Human Glioblastoma Cells , 2012, PloS one.
[26] G. Fuller,et al. REST regulates oncogenic properties of glioblastoma stem cells. , 2012, Stem cells.
[27] M. Bennett,et al. Repressor element-1 silencing transcription factor (REST)-dependent epigenetic remodeling is critical to ischemia-induced neuronal death , 2012, Proceedings of the National Academy of Sciences.
[28] G. Fuller,et al. Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCFβ‐TRCP in neuroblastoma cells , 2011, Cancer.
[29] R. Gainetdinov,et al. The Physiology, Signaling, and Pharmacology of Dopamine Receptors , 2011, Pharmacological Reviews.
[30] K. Aldape,et al. NFKBIA deletion in glioblastomas. , 2011, The New England journal of medicine.
[31] J. Rees. Neuro-oncology , 2010, Practical Neurology.
[32] P. Dirks,et al. Brain tumor stem cells: The cancer stem cell hypothesis writ large , 2010, Molecular oncology.
[33] G. Fuller,et al. Myoblast‐Derived Neuronal Cells Form Glutamatergic Neurons in the Mouse Cerebellum , 2010, Stem cells.
[34] R. Wilson,et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. , 2010, Cancer cell.
[35] S. Gabriel,et al. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. , 2010, Cancer cell.
[36] R. Prayson,et al. The pathobiology of glioma tumors. , 2010, Annual review of pathology.
[37] M. Rocchi,et al. The Rest Repression of the Neurosecretory Phenotype Is Negatively Modulated by BHC80, a Protein of the BRAF/HDAC Complex , 2009, The Journal of Neuroscience.
[38] J. Coulson,et al. SCG3 Transcript in Peripheral Blood Is a Prognostic Biomarker for REST-Deficient Small Cell Lung Cancer , 2009, Clinical Cancer Research.
[39] Thomas D. Wu,et al. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. , 2006, Cancer cell.
[40] K. Aldape,et al. Abnormal Expression of REST/NRSF and Myc in Neural Stem/Progenitor Cells Causes Cerebellar Tumors by Blocking Neuronal Differentiation , 2006, Molecular and Cellular Biology.
[41] G. Mandel,et al. The many faces of REST oversee epigenetic programming of neuronal genes , 2005, Current Opinion in Neurobiology.
[42] R. Price,et al. Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16 , 2005, Molecular Cancer Therapeutics.
[43] S. Kameoka,et al. Activation of REST/NRSF Target Genes in Neural Stem Cells Is Sufficient To Cause Neuronal Differentiation , 2004, Molecular and Cellular Biology.
[44] K. Aldape,et al. Conversion of myoblasts to physiologically active neuronal phenotype. , 2004, Genes & development.
[45] J. Morris,et al. REST-VP16 activates multiple neuronal differentiation genes in human NT2 cells. , 2000, Nucleic acids research.
[46] G. Fuller,et al. The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells , 2000, Nature Medicine.
[47] Gail Mandel,et al. REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons , 1995, Cell.
[48] D J Anderson,et al. The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes , 1995, Science.
[49] R. Arceci. Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma , 2010 .
[50] Mohamedi N. Kagalwala,et al. Stemness is only a state of the cell. , 2008, Cold Spring Harbor symposia on quantitative biology.
[51] A. Mortazavi,et al. network : From single conserved sites to genome-wide repertoire Comparative genomics modeling of the NRSF / REST repressor Material Supplemental , 2006 .
[52] J. Deuchars,et al. Distinct profiles of REST interactions with its target genes at different stages of neuronal development. , 2005, Molecular biology of the cell.