Nocturnal asthma is affected by genetic interactions between RORA and NPSR1

Neuropeptide S Receptor 1 ( NPSR1) and Retinoid Acid Receptor‐Related Orphan Receptor Alpha (RORA ) interact biologically, are both known candidate genes for asthma, and are involved in controlling circadian rhythm. Thus, we assessed (1) whether interactions between RORA and NPSR1 specifically affect the nocturnal asthma phenotype and (2) how this may differ from other asthma phenotypes.

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