Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover
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S. Cohen | Rajat Gupta | Chunaram Choudhary | Xin Hong | A. Loya | P. J. Eichhorn | D. Andrējeva | Hung Thanh Nguyen
[1] Xiaocan Guo,et al. YAP activates the Hippo pathway in a negative feedback loop , 2017, Cell Research.
[2] D. Lim,et al. Role of Angiomotin‐like 2 mono‐ubiquitination on YAP inhibition , 2016, EMBO reports.
[3] Min Wang,et al. Upregulation of miR-181c contributes to chemoresistance in pancreatic cancer by inactivating the Hippo signaling pathway , 2015, Oncotarget.
[4] M. Karin,et al. A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis , 2015, Genes & development.
[5] Antonio Marchetti,et al. The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies , 2015, Nature Genetics.
[6] Kun-Liang Guan,et al. The emerging roles of YAP and TAZ in cancer , 2015, Nature Reviews Cancer.
[7] K. Guan,et al. Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway , 2014, Oncogene.
[8] S. Cohen,et al. Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover , 2014, The EMBO journal.
[9] S. Cohen,et al. Viral small T oncoproteins transform cells by alleviating hippo-pathway-mediated inhibition of the YAP proto-oncogene. , 2014, Cell reports.
[10] Shan Jiang,et al. Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer , 2014, Cell.
[11] Joseph Rosenbluh,et al. KRAS and YAP1 Converge to Regulate EMT and Tumor Survival , 2014, Cell.
[12] Peng Qiu,et al. TCGA-Assembler: open-source software for retrieving and processing TCGA data , 2014, Nature Methods.
[13] G. Tonon,et al. RESCUE OF HIPPO CO-ACTIVATOR YAP1 TRIGGERS DNA DAMAGE-INDUCED APOPTOSIS IN HEMATOLOGICAL CANCERS , 2014, Nature Medicine.
[14] G. Halder,et al. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment , 2013, Nature Reviews Drug Discovery.
[15] W. Hong,et al. Actin-binding and Cell Proliferation Activities of Angiomotin Family Members Are Regulated by Hippo Pathway-mediated Phosphorylation* , 2013, The Journal of Biological Chemistry.
[16] Benjamin J. Raphael,et al. Mutational landscape and significance across 12 major cancer types , 2013, Nature.
[17] Yiqiang Zhao,et al. Phosphorylation of Angiomotin by Lats1/2 Kinases Inhibits F-actin Binding, Cell Migration, and Angiogenesis* , 2013, The Journal of Biological Chemistry.
[18] A. Brunetti,et al. Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth , 2013, Nature Communications.
[19] M. Goebl,et al. Amot130 Adapts Atrophin-1 Interacting Protein 4 to Inhibit Yes-associated Protein Signaling and Cell Growth* , 2013, The Journal of Biological Chemistry.
[20] F. Camargo,et al. The Hippo superhighway: signaling crossroads converging on the Hippo/Yap pathway in stem cells and development. , 2013, Current opinion in cell biology.
[21] David M. Thomas,et al. The Hippo pathway and human cancer , 2013, Nature Reviews Cancer.
[22] M. Kirschner,et al. Deubiquitinase FAM/USP9X Interacts with the E3 Ubiquitin Ligase SMURF1 Protein and Protects It from Ligase Activity-dependent Self-degradation , 2012, The Journal of Biological Chemistry.
[23] Lincoln D. Stein,et al. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes , 2012, Nature.
[24] Chunaram Choudhary,et al. Proteomic Analyses Reveal Divergent Ubiquitylation Site Patterns in Murine Tissues* , 2012, Molecular & Cellular Proteomics.
[25] Jun O. Liu,et al. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. , 2012, Genes & development.
[26] Jun O. Liu,et al. The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation. , 2012, The Biochemical journal.
[27] Richard J. Lavallee,et al. Optimized fast and sensitive acquisition methods for shotgun proteomics on a quadrupole orbitrap mass spectrometer. , 2012, Journal of proteome research.
[28] G. Kristiansen,et al. The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma , 2012, Nature.
[29] J. Baselga,et al. USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma , 2012, Nature Medicine.
[30] J. Yates,et al. Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor , 2011, Molecular biology of the cell.
[31] Sebastian A. Wagner,et al. A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles* , 2011, Molecular & Cellular Proteomics.
[32] Nicola Elvassore,et al. Role of YAP/TAZ in mechanotransduction , 2011, Nature.
[33] R. Aqeilan,et al. Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity. , 2011, Cancer research.
[34] M. Mann,et al. Andromeda: a peptide search engine integrated into the MaxQuant environment. , 2011, Journal of proteome research.
[35] A. Pobbati,et al. Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin* , 2011, The Journal of Biological Chemistry.
[36] Junjie Chen,et al. Angiomotin-like Proteins Associate with and Negatively Regulate YAP1* , 2010, The Journal of Biological Chemistry.
[37] A. Bowcock,et al. Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas , 2010, Science.
[38] N. Donato,et al. Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis. , 2010, Cancer research.
[39] Zhengyu Zha,et al. The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase* , 2010, The Journal of Biological Chemistry.
[40] Li Li,et al. The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. , 2010, Genes & development.
[41] F. Bazan,et al. Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival , 2010, Nature.
[42] H. Ichijo,et al. Ubiquitin-like sequence in ASK1 plays critical roles in the recognition and stabilization by USP9X and oxidative stress-induced cell death. , 2009, Molecular cell.
[43] Jianmin Zhang,et al. YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway , 2009, Nature Cell Biology.
[44] Leonardo Morsut,et al. FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination , 2009, Cell.
[45] K. Guan,et al. The Hippo-YAP pathway: new connections between regulation of organ size and cancer. , 2008, Current opinion in cell biology.
[46] M. Mann,et al. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification , 2008, Nature Biotechnology.
[47] Li Li,et al. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. , 2007, Genes & development.
[48] M. Mann,et al. Higher-energy C-trap dissociation for peptide modification analysis , 2007, Nature Methods.
[49] Steven P Gygi,et al. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry , 2007, Nature Methods.
[50] P. McPherson,et al. The Ubiquitin Ligase Itch Is Auto-ubiquitylated in Vivo and in Vitro but Is Protected from Degradation by Interacting with the Deubiquitylating Enzyme FAM/USP9X* , 2006, Journal of Biological Chemistry.
[51] M. Mann,et al. Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks , 2006, Cell.
[52] Jianmin Zhang,et al. Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon , 2006, Proceedings of the National Academy of Sciences.
[53] Mariette Schrier,et al. A Genetic Screen Implicates miRNA-372 and miRNA-373 As Oncogenes in Testicular Germ Cell Tumors , 2006, Cell.
[54] A. Rao. Faculty Opinions recommendation of Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB. , 2003 .
[55] René Bernards,et al. Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-κB , 2003, Nature.
[56] Matthias Mann,et al. Mass spectrometric-based approaches in quantitative proteomics. , 2003, Methods.
[57] R. Bernards,et al. A System for Stable Expression of Short Interfering RNAs in Mammalian Cells , 2002, Science.
[58] A. Ashworth,et al. Identification of the familial cylindromatosis tumour-suppressor gene , 2000, Nature Genetics.
[59] G. Kristiansen,et al. The deubiquitinase USP 9 X suppresses pancreatic ductal adenocarcinoma , 2012 .
[60] K. Guan,et al. Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. , 2011, Genes & development.
[61] K. Guan,et al. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). , 2010, Genes & development.
[62] Leonardo Morsut,et al. FAM / USP 9 x , a Deubiquitinating Enzyme Essential for TGF b Signaling , Controls Smad 4 Monoubiquitination , 2009 .