Both postnatal and postmenstrual age contribute to the interindividual variability in tramadol glucuronidation in neonates.

[1]  D. Tibboel,et al.  O-demethylation of tramadol in the first months of life , 2005, European Journal of Clinical Pharmacology.

[2]  D. Tibboel,et al.  Intra‐ and interindividual variability of glucuronidation of paracetamol during repeated administration of propacetamol in neonates , 2005, Acta paediatrica.

[3]  J. Anker.  Managing drugs safely. , 2005 .

[4]  G. Naulaers,et al.  Continuous infusion of medications in very low birth weight infants , 2004, European Journal of Clinical Pharmacology.

[5]  P. G. Wells,et al.  Glucuronidation and the UDP-glucuronosyltransferases in health and disease. , 2004, Drug metabolism and disposition: the biological fate of chemicals.

[6]  D. Tibboel,et al.  Developmental pharmacokinetics of morphine and its metabolites in neonates, infants and young children. , 2004, British journal of anaesthesia.

[7]  Susan M Abdel-Rahman,et al.  Developmental pharmacology--drug disposition, action, and therapy in infants and children. , 2003, The New England journal of medicine.

[8]  D. Tibboel,et al.  Paracetamol and metabolite pharmacokinetics in infants , 2003, European Journal of Clinical Pharmacology.

[9]  J. Carcillo,et al.  Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure , 2003, Intensive Care Medicine.

[10]  D. Tibboel,et al.  Systematic evaluation of pain in neonates: effect on the number of intravenous analgesics prescribed , 2003, European Journal of Clinical Pharmacology.

[11]  R. Boulieu,et al.  Propofol metabolites in man following propofol induction and maintenance. , 2002, British journal of anaesthesia.

[12]  D. G. McCarver,et al.  The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms. , 2002, The Journal of pharmacology and experimental therapeutics.

[13]  J. Steven Leeder,et al.  Glucuronidation in Humans , 1999, Clinical pharmacokinetics.

[14]  R. V. van Lingen,et al.  Pharmacokinetics and metabolism of rectally administered paracetamol in preterm neonates , 1999, Archives of disease in childhood. Fetal and neonatal edition.

[15]  S. Domke,et al.  Maturation of hepatosomal mono‐oxygenation and glucuronidation activities in pre‐ and full‐term infants as studied using the [15N]methacetin urine test , 1997, Acta paediatrica.

[16]  J. Anker.  Pharmacokinetics and renal function in preterm infants , 1996 .

[17]  I. Choonara,et al.  Morphine metabolism in children. , 1989 .

[18]  D. Tibboel,et al.  Contribution of glucuronidation to tramadol disposition in early neonatal life. , 2006, Basic & clinical pharmacology & toxicology.

[19]  S. Grond,et al.  Clinical Pharmacology of Tramadol , 2004, Clinical pharmacokinetics.

[20]  K. Allegaert,et al.  Nephelometry to study compatibility of intravenous drugs in neonates: experience with tramadol , 2004 .

[21]  L. Mofenson,et al.  Pharmacokinetics and tolerance of zidovudine in preterm infants. , 2003, The Journal of pediatrics.