Insulin alleviates degradation of skeletal muscle protein by inhibiting the ubiquitin-proteasome system in septic rats

[1]  Deborah J. Cook,et al.  Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data , 2009, Canadian Medical Association Journal.

[2]  Jie Du,et al.  Cardiac muscle protein catabolism in diabetes mellitus: activation of the ubiquitin-proteasome system by insulin deficiency. , 2008, Endocrinology.

[3]  W. Mitch,et al.  Muscle wasting in chronic kidney disease: the role of the ubiquitin proteasome system and its clinical impact , 2008, Pediatric Nephrology.

[4]  B. Ahlman,et al.  Proteasome proteolytic activity in skeletal muscle is increased in patients with sepsis. , 2007, Clinical science.

[5]  D. Hazlerigg,et al.  Amino acids and insulin act additively to regulate components of the ubiquitin-proteasome pathway in C2C12 myotubes , 2007, BMC Molecular Biology.

[6]  W. Mitch,et al.  Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. , 2006, Endocrinology.

[7]  G. Van den Berghe,et al.  Intensive insulin therapy in the medical ICU. , 2006, The New England journal of medicine.

[8]  M. Drost,et al.  Ubiquitin-proteasome-dependent proteolytic activity remains elevated after zymosan-induced sepsis in rats while muscle mass recovers. , 2005, The international journal of biochemistry & cell biology.

[9]  S. Wing Control of ubiquitination in skeletal muscle wasting. , 2005, The international journal of biochemistry & cell biology.

[10]  M. Tisdale The ubiquitin-proteasome pathway as a therapeutic target for muscle wasting. , 2005, The journal of supportive oncology.

[11]  Shih-Yi Lin,et al.  Activation of ubiquitin-proteasome pathway is involved in skeletal muscle wasting in a rat model with biliary cirrhosis: potential role of TNF-alpha. , 2005, American journal of physiology. Endocrinology and metabolism.

[12]  R. A. Butler,et al.  A HECT E3 ubiquitin-protein ligase with sequence similarity to E6AP does not target p53 for degradation in the softshell clam (Mya arenaria). , 2004, Mutation research.

[13]  N. Espat,et al.  The ubiquitin-proteasome proteolysis pathway: potential target for disease intervention. , 2004, JPEN. Journal of parenteral and enteral nutrition.

[14]  W. Mitch,et al.  Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase. , 2004, Journal of the American Society of Nephrology : JASN.

[15]  G. Yancopoulos,et al.  The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. , 2004, Molecular cell.

[16]  Ning Li,et al.  Influence of acute hyperglycemia in human sepsis on inflammatory cytokine and counterregulatory hormone concentrations. , 2003, World journal of gastroenterology.

[17]  Yanqiu Wu,et al.  Role of ubiquitin-proteasome pathway in skeletal muscle wasting in rats with endotoxemia. , 2003, Critical care medicine.

[18]  P. Hasselgren,et al.  Sepsis upregulates the gene expression of multiple ubiquitin ligases in skeletal muscle. , 2003, The international journal of biochemistry & cell biology.

[19]  R. Mitchell,et al.  Antiproteolytic action of insulin in burn-injured rats. , 2002, The Journal of surgical research.

[20]  R. Tompkins,et al.  Inducible nitric oxide synthase plays a role in LPS-induced hyperglycemia and insulin resistance. , 2002, American journal of physiology. Endocrinology and metabolism.

[21]  S. Madihally,et al.  Insulin suppresses the increased activities of lysosomal cathepsins and ubiquitin conjugation system in burn-injured rats. , 2000, The Journal of surgical research.

[22]  B. Bistrian,et al.  Metabolic effects of insulin and insulin-like growth factor-I in endotoxemic rats during total parenteral nutrition feeding. , 2000, Metabolism: clinical and experimental.

[23]  Claudine Jurkovitz,et al.  Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting. , 1999, American journal of physiology. Cell physiology.

[24]  P. Hasselgren Role of the ubiquitin-proteasome pathway in sepsis-induced muscle catabolism , 1999, Molecular Biology Reports.

[25]  J. Fischer,et al.  Sepsis is associated with increased ubiquitinconjugating enzyme E214k mRNA in skeletal muscle. , 1999, American journal of physiology. Regulatory, integrative and comparative physiology.

[26]  W. Duckworth,et al.  Insulin inhibition of proteasome activity in intact cells. , 1997, Biochemical and biophysical research communications.

[27]  J. Fischer,et al.  The ubiquitin-proteasome pathway: review of a novel intracellular mechanism of muscle protein breakdown during sepsis and other catabolic conditions. , 1997, Annals of surgery.

[28]  T. Meyer,et al.  Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle. , 1997, The Journal of clinical investigation.

[29]  N. Agell,et al.  TNF can directly induce the expression of ubiquitin-dependent proteolytic system in rat soleus muscles. , 1997, Biochemical and biophysical research communications.

[30]  L. Phillips,et al.  Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome proteolytic pathway by a mechanism including gene transcription. , 1996, The Journal of clinical investigation.

[31]  D. Taillandier,et al.  Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging. , 1995, The Journal of clinical investigation.

[32]  W. Duckworth,et al.  A direct inhibitory effect of insulin on a cytosolic proteolytic complex containing insulin-degrading enzyme and multicatalytic proteinase. , 1994, The Journal of biological chemistry.

[33]  S. Wing,et al.  14-kDa ubiquitin-conjugating enzyme: structure of the rat gene and regulation upon fasting and by insulin. , 1994, The American journal of physiology.

[34]  D. Glass PI3 kinase regulation of skeletal muscle hypertrophy and atrophy. , 2010, Current topics in microbiology and immunology.

[35]  Ning Li,et al.  [Influence and mechanism of a tight control of blood glucose by intensive insulin therapy on human sepsis]. , 2005, Zhonghua wai ke za zhi [Chinese journal of surgery].

[36]  C. Slaughter,et al.  Regulatory proteins of the proteasome. , 1993, Enzyme & protein.