Potent Inhibition of hERG Channels by the Over-the-Counter Antidiarrheal Agent Loperamide.

[1]  R. Chou,et al.  CDC Guideline for Prescribing Opioids for Chronic Pain--United States, 2016. , 2016, JAMA.

[2]  R. Hoffman,et al.  Not your regular high: cardiac dysrhythmias caused by loperamide , 2016, Clinical toxicology.

[3]  Imir G. Metushi,et al.  High-dose loperamide abuse–associated ventricular arrhythmias , 2016, HeartRhythm case reports.

[4]  A. Tripathi,et al.  Multilayer Spheroids To Quantify Drug Uptake and Diffusion in 3D , 2014, Molecular pharmaceutics.

[5]  Sujan Perera,et al.  "I just wanted to tell you that loperamide WILL WORK": a web-based study of extra-medical use of loperamide. , 2013, Drug and alcohol dependence.

[6]  J. Valentin,et al.  On the relationship between block of the cardiac Na+ channel and drug‐induced prolongation of the QRS complex , 2011, British journal of pharmacology.

[7]  M. Krantz,et al.  QTc Interval Screening in Methadone Treatment , 2009, Annals of Internal Medicine.

[8]  H. Meadows,et al.  Improved functional expression of recombinant human ether-a-go-go (hERG) K+ channels by cultivation at reduced temperature , 2007, BMC biotechnology.

[9]  A. Camm,et al.  Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. , 2003, Cardiovascular research.

[10]  A. Katchman,et al.  Influence of Opioid Agonists on Cardiac HumanEther-a-go-go-related Gene K+ Currents , 2002, Journal of Pharmacology and Experimental Therapeutics.

[11]  Pamela N. Peterson,et al.  Torsade de Pointes Associated with High-dose Loperamide Ingestion , 2015 .