Predictors of progression of osteoarthritis in femoroacetabular impingement: a radiological study with a minimum of ten years follow-up.

Although the association between femoroacetabular impingement and osteoarthritis is established, it is not yet clear which hips have the greatest likelihood to progress rapidly to end-stage disease. We investigated the effect of several radiological parameters, each indicative of a structural aspect of the hip joint, on the progression of osteoarthritis. Pairs of plain anteroposterior pelvic radiographs, taken at least ten years apart, of 43 patients (43 hips) with a pistol-grip deformity of the femur and mild (Tönnis grade 1) or moderate (Tönnis grade 2) osteoarthritis were reviewed. Of the 43 hips, 28 showed evidence of progression of osteoarthritis. There was no significant difference in the prevalence of progression between hips with initial Tönnis grade 1 or grade 2 osteoarthritis (p = 0.31). Comparison of the hips with and without progression of arthritis revealed a significant difference in the mean medial proximal femoral angle (81 degrees vs 87 degrees, p = 0.004) and the presence of the posterior wall sign (39% vs 7%, p = 0.02) only. A logistic regression model was constructed to predict the influence of these two variables in the development of osteoarthritis. Mild to moderate osteoarthritis in hips with a pistol-grip deformity will not progress rapidly in all patients. In one-third, progression will take more than ten years to manifest, if ever. The individual geometry of the proximal femur and acetabulum partly influences this phenomenon. A hip with cam impingement is not always destined for end-stage arthritic degeneration.

[1]  R. Ganz,et al.  Acetabular Rim Degeneration: A Constant Finding in the Aged Hip , 2003, Clinical orthopaedics and related research.

[2]  R. Ganz,et al.  Hip morphology influences the pattern of damage to the acetabular cartilage: femoroacetabular impingement as a cause of early osteoarthritis of the hip. , 2005, The Journal of bone and joint surgery. British volume.

[3]  Michael Tanzer,et al.  Osseous Abnormalities and Early Osteoarthritis: The Role of Hip Impingement , 2004, Clinical orthopaedics and related research.

[4]  R. Trousdale,et al.  Protrusio Acetabuli: Diagnosis and Treatment , 2001, The Journal of the American Academy of Orthopaedic Surgeons.

[5]  Dror Paley,et al.  Normal lower limb alignment and joint orientation , 2002 .

[6]  D. Paley Hip Joint Considerations , 2002 .

[7]  R. Ganz,et al.  Femoroacetabular impingement: a cause for osteoarthritis of the hip. , 2003, Clinical orthopaedics and related research.

[8]  H. Wagner Femoral Osteotomies For Congenital Hip Dislocation , 1978 .

[9]  T. Nakamura,et al.  Primary osteoarthritis of the hip joint in Japan. , 1989, Clinical orthopaedics and related research.

[10]  John M. Clark,et al.  Correlation Between Internal Rotation and Bony Anatomy in the Hip , 2007, Clinical orthopaedics and related research.

[11]  K. Søballe,et al.  Weightbearing Anteroposterior Pelvic Radiographs are Recommended in DDH Assessment , 2008, Clinical orthopaedics and related research.

[12]  A. Heinecke,et al.  Acetabular and femoral anteversion: relationship with osteoarthritis of the hip. , 1999, The Journal of bone and joint surgery. American volume.

[13]  W. Harris Etiology of osteoarthritis of the hip. , 1986, Clinical orthopaedics and related research.

[14]  Y H Chan,et al.  Biostatistics 202: logistic regression analysis. , 2004, Singapore medical journal.

[15]  Marc Puls,et al.  Pathomorphologic Alterations Predict Presence or Absence of Hip Osteoarthrosis , 2007, Clinical orthopaedics and related research.

[16]  S B Murphy,et al.  Range of Motion in Anterior Femoroacetabular Impingement , 2007, Clinical orthopaedics and related research.

[17]  T. Youm,et al.  Femoroacetabular impingement--diagnosis and treatment. , 2010, Bulletin of the NYU hospital for joint diseases.

[18]  J. Mccarthy,et al.  The watershed labral lesion: its relationship to early arthritis of the hip. , 2001, The Journal of arthroplasty.

[19]  K. Klaue,et al.  Retroversion of the acetabulum. A cause of hip pain. , 1999, The Journal of bone and joint surgery. British volume.

[20]  D. Tönnis Normal values of the hip joint for the evaluation of X-rays in children and adults. , 1976, Clinical orthopaedics and related research.

[21]  A. Petrie,et al.  Statistics in orthopaedic papers. , 2006, The Journal of bone and joint surgery. British volume.

[22]  E. Morscher,et al.  Femoral neck lengthening osteotomy after growth disturbance of the proximal femur. , 1999, Journal of pediatric orthopedics. Part B.

[23]  R. Trousdale,et al.  Acetabular Labral Tears Rarely Occur in the Absence of Bony Abnormalities , 2004, Clinical orthopaedics and related research.

[24]  R. Ganz,et al.  Femoroacetabular impingement and the cam-effect. A MRI-based quantitative anatomical study of the femoral head-neck offset. , 2001, The Journal of bone and joint surgery. British volume.

[25]  Dror Paley,et al.  Principles of Deformity Correction , 2003 .

[26]  J. Hodler,et al.  The contour of the femoral head-neck junction as a predictor for the risk of anterior impingement. , 2002, The Journal of bone and joint surgery. British volume.

[27]  R. Ganz,et al.  Comparison of Six Radiographic Projections to Assess Femoral Head/Neck Asphericity , 2006, Clinical orthopaedics and related research.

[28]  J. Mccarthy,et al.  The Role of Labral Lesions to Development of Early Degenerative Hip Disease , 2001, Clinical orthopaedics and related research.

[29]  Hideki Yoshikawa,et al.  Open‐configuration MRI study of femoro‐acetabular impingement , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[30]  Erling B. Andersen,et al.  Logistic Regression Analysis , 1994 .

[31]  R. Ganz,et al.  Anterior Femoro-Acetabular Impingement Due to Acetabular Retroversion: Treatment with Periacetabular Osteotomy , 2003, The Journal of bone and joint surgery. American volume.

[32]  G. Wiberg,et al.  Studies on dysplastic acetabula and congenital subluxation of the hip joint : with special reference to the complication of osteoarthritis , 1939 .

[33]  S. Jacobsen,et al.  A new radiological index for assessing asphericity of the femoral head in cam impingement. , 2007, The Journal of bone and joint surgery. British volume.