Microbial cyclophilins: specialized functions in virulence and beyond

[1]  M. Zouhar,et al.  Cyclophilins: Less Studied Proteins with Critical Roles in Pathogenesis. , 2018, Phytopathology.

[2]  P. Katinakis,et al.  Functional analysis of the cyclophilin PpiB role in bacterial cell division , 2017, Genes to cells : devoted to molecular & cellular mechanisms.

[3]  C. Ho,et al.  Molecular cloning and expression analysis of Ganoderma boninense cyclophilins at different growth and infection stages , 2017 .

[4]  S. Ying,et al.  Vital role for cyclophilin B (CypB) in asexual development, dimorphic transition and virulence of Beauveria bassiana. , 2017, Fungal genetics and biology : FG & B.

[5]  S. Barik.  On the role, ecology, phylogeny, and structure of dual-family immunophilins , 2017, Cell Stress and Chaperones.

[6]  Eun-Young Kim,et al.  Effects of the cyclophilin-type peptidylprolyl cis-trans isomerase from Pyropia yezoensis against hydrogen peroxide-induced oxidative stress in HepG2 cells , 2017, Molecular medicine reports.

[7]  Ashutosh Kumar,et al.  Mycobacterium tuberculosis Peptidyl-Prolyl Isomerases Are Immunogenic, Alter Cytokine Profile and Aid in Intracellular Survival , 2017, Front. Cell. Infect. Microbiol..

[8]  J. Bua,et al.  A homolog of cyclophilin D is expressed in Trypanosoma cruzi and is involved in the oxidative stress–damage response , 2017, Cell Death Discovery.

[9]  P. Katinakis,et al.  Functional analysis of the two cyclophilin isoforms of Sinorhizobium meliloti , 2017, World journal of microbiology & biotechnology.

[10]  M. Karpusas,et al.  Structural and functional analysis of cyclophilin PpiB mutants supports an in vivo function not limited to prolyl isomerization activity , 2017, Genes to cells : devoted to molecular & cellular mechanisms.

[11]  Ronan K. Carroll,et al.  An Intracellular Peptidyl-Prolyl cis/trans Isomerase Is Required for Folding and Activity of the Staphylococcus aureus Secreted Virulence Factor Nuclease , 2016, Journal of bacteriology.

[12]  Y. Pei,et al.  Dissection of the contributions of cyclophilin genes to development and virulence in a fungal insect pathogen. , 2016, Environmental microbiology.

[13]  N. Reiner,et al.  Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant , 2016, The Journal of eukaryotic microbiology.

[14]  Liming Shi,et al.  Comparative Secretome Analysis Reveals Perturbation of Host Secretion Pathways by a Hypovirus , 2016, Scientific Reports.

[15]  A. Rementeria,et al.  Cyclophilin and enolase are the most prevalent conidial antigens of Lomentospora prolificans recognized by healthy human salivary IgA and cross‐react with Aspergillus fumigatus , 2016, Proteomics. Clinical applications.

[16]  R. Jakob,et al.  Structural and Functional Characterization of a Novel Family of Cyclophilins, the AquaCyps , 2016, PloS one.

[17]  P. Katinakis,et al.  Cyclophilin PpiB is involved in motility and biofilm formation via its functional association with certain proteins , 2016, Genes to cells : devoted to molecular & cellular mechanisms.

[18]  V. Dubey,et al.  Quantitative Proteome Analysis of Leishmania donovani under Spermidine Starvation , 2016, PloS one.

[19]  M. Ivanchenko,et al.  Master and servant: Regulation of auxin transporters by FKBPs and cyclophilins. , 2016, Plant science : an international journal of experimental plant biology.

[20]  R. Guo,et al.  A novel cyclophilin gene from the dinoflagellate Prorocentrum minimum and its possible role in the environmental stress response. , 2015, Chemosphere.

[21]  C. Baines,et al.  Structural mechanisms of cyclophilin D-dependent control of the mitochondrial permeability transition pore. , 2015, Biochimica et biophysica acta.

[22]  S. Luan,et al.  Plant immunophilins: a review of their structure-function relationship. , 2015, Biochimica et biophysica acta.

[23]  D. Hamelberg,et al.  Computational perspective and evaluation of plausible catalytic mechanisms of peptidyl-prolyl cis-trans isomerases. , 2015, Biochimica et biophysica acta.

[24]  D. Sharma,et al.  Hsp90-Associated Immunophilin Homolog Cpr7 Is Required for the Mitotic Stability of [URE3] Prion in Saccharomyces cerevisiae , 2015, PLoS genetics.

[25]  A. Bell,et al.  Immunophilin–protein interactions in Plasmodium falciparum , 2015, Parasitology.

[26]  E. Eisenmesser,et al.  Structure and Dynamics of GeoCyp: A Thermophilic Cyclophilin with a Novel Substrate Binding Mechanism That Functions Efficiently at Low Temperatures. , 2015, Biochemistry.

[27]  C. Dickey,et al.  The emerging role of peptidyl‐prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease , 2015, Journal of neurochemistry.

[28]  P. Gallay,et al.  The role of immunophilins in viral infection , 2014, Biochimica et Biophysica Acta (BBA) - General Subjects.

[29]  M. Bukrinsky.  Extracellular cyclophilins in health and disease , 2014, Biochimica et Biophysica Acta (BBA) - General Subjects.

[30]  A. Romanha,et al.  Molecular characterization of Cyclophilin (TcCyP19) in Trypanosoma cruzi populations susceptible and resistant to benznidazole. , 2015, Experimental parasitology.

[31]  T. Ratajczak.  Steroid Receptor-Associated Immunophilins: Candidates for Diverse Drug-Targeting Approaches in Disease. , 2015, Current molecular pharmacology.

[32]  T. Pupko,et al.  Revealing bacterial targets of growth inhibitors encoded by bacteriophage T7 , 2014, Proceedings of the National Academy of Sciences.

[33]  M. Wahl,et al.  Structure and evolution of the spliceosomal peptidyl-prolyl cis-trans isomerase Cwc27. , 2014, Acta crystallographica. Section D, Biological crystallography.

[34]  Victoria R. Tenge,et al.  The Hsp90 Cochaperones Cpr6, Cpr7, and Cns1 Interact with the Intact Ribosome , 2014, Eukaryotic Cell.

[35]  M. Zouhar,et al.  Genome wide identification of the immunophilin gene family in Leptosphaeria maculans: a causal agent of Blackleg disease in Oilseed Rape (Brassica napus). , 2014, Omics : a journal of integrative biology.

[36]  M. Steinert,et al.  Microbial Peptidyl-Prolyl cis/trans Isomerases (PPIases): Virulence Factors and Potential Alternative Drug Targets , 2014, Microbiology and Molecular Reviews.

[37]  R. Sturrock,et al.  Gene expression profiling of candidate virulence factors in the laminated root rot pathogen Phellinus sulphurascens , 2014, BMC Genomics.

[38]  M. Wiese,et al.  The Leishmania donovani chaperone cyclophilin 40 is essential for intracellular infection independent of its stage‐specific phosphorylation status , 2014, Molecular microbiology.

[39]  H. Furuoka,et al.  Overproduction of Toxoplasma gondii cyclophilin-18 regulates host cell migration and enhances parasite dissemination in a CCR5-independent manner , 2014, BMC Microbiology.

[40]  J. S. Virdi,et al.  Mycobacterium tuberculosis Cyclophilin A Uses Novel Signal Sequence for Secretion and Mimics Eukaryotic Cyclophilins for Interaction with Host Protein Repertoire , 2014, PloS one.

[41]  A. Rementeria,et al.  Scedosporium prolificans immunomes against human salivary immunoglobulin A. , 2014, Fungal biology.

[42]  N. Tuteja,et al.  Molecular characterization of cyclophilin A-like protein from Piriformospora indica for its potential role to abiotic stress tolerance in E. coli , 2013, BMC Research Notes.

[43]  X. Cai,et al.  Cyclophilin A from Schistosoma japonicum promotes a Th2 response in mice , 2013, Parasites & Vectors.

[44]  N. Tuteja,et al.  Structure of RNA-interacting Cyclophilin A-like protein from Piriformospora indica that provides salinity-stress tolerance in plants , 2013, Scientific Reports.

[45]  T. Arimoto,et al.  Involvement of lipoprotein PpiA of Streptococcus gordonii in evasion of phagocytosis by macrophages. , 2013, Molecular oral microbiology.

[46]  P. Nigro,et al.  Cyclophilin A: a key player for human disease , 2013, Cell Death and Disease.

[47]  A. Dasgupta,et al.  Cyclophilin-mediated reactivation pathway of inactive adenosine kinase aggregates. , 2013, Archives of biochemistry and biophysics.

[48]  Jason S. Cumbie,et al.  The Genome of Tolypocladium inflatum: Evolution, Organization, and Expression of the Cyclosporin Biosynthetic Gene Cluster , 2013, PLoS genetics.

[49]  Jin-Song Wang,et al.  PPIase independent chaperone‐like function of recombinant human Cyclophilin A during arginine kinase refolding , 2013, FEBS letters.

[50]  Vinay Panwar,et al.  Host-induced gene silencing of wheat leaf rust fungus Puccinia triticina pathogenicity genes mediated by the Barley stripe mosaic virus , 2013, Plant Molecular Biology.

[51]  B. McGwire,et al.  Secreted Trypanosome Cyclophilin Inactivates Lytic Insect Defense Peptides and Induces Parasite Calcineurin Activation and Infectivity* , 2013, The Journal of Biological Chemistry.

[52]  G. Fischer,et al.  Peptide bond cis/trans isomerases: a biocatalysis perspective of conformational dynamics in proteins. , 2013, Topics in current chemistry.

[53]  V. DelVecchio,et al.  Intracellularly Induced Cyclophilins Play an Important Role in Stress Adaptation and Virulence of Brucella abortus , 2012, Infection and Immunity.

[54]  P. Katinakis,et al.  Functional interaction of Azotobacter vinelandii cytoplasmic cyclophilin with the biotin carboxylase subunit of acetyl-CoA carboxylase. , 2012, Biochemical and biophysical research communications.

[55]  Z. Fu,et al.  Molecular cloning and characterization of a cyclophilin A homologue from Schistosoma japonicum , 2012, Parasitology Research.

[56]  Donald Hamelberg,et al.  Resolving the complex role of enzyme conformational dynamics in catalytic function , 2012, Proceedings of the National Academy of Sciences.

[57]  J. Gratadoux,et al.  PpiA, a Surface PPIase of the Cyclophilin Family in Lactococcus lactis , 2012, PloS one.

[58]  M. Karpusas,et al.  Structure of a bacterial cytoplasmic cyclophilin A in complex with a tetrapeptide. , 2012, Acta crystallographica. Section F, Structural biology and crystallization communications.

[59]  S. Chevalier,et al.  Involvement of Peptidylprolyl cis/trans Isomerases in Enterococcus faecalis Virulence , 2012, Infection and Immunity.

[60]  J. Qin,et al.  The TPR Domain in the Host Cyp40-like Cyclophilin Binds to the Viral Replication Protein and Inhibits the Assembly of the Tombusviral Replicase , 2012, PLoS pathogens.

[61]  R. Terauchi,et al.  Use of intercellular washing fluid to investigate the secreted proteome of the rice–Magnaporthe interaction , 2012, Journal of Plant Research.

[62]  P. Katinakis,et al.  The cytoplasmic cyclophilin from Azotobacter vinelandii interacts with phosphate acetyltransferase isoforms enhancing their in vitro activity , 2012, Molecular Biology Reports.

[63]  M. S. Francis,et al.  Varying dependency of periplasmic peptidylprolyl cis-trans isomerases in promoting Yersinia pseudotuberculosis stress tolerance and pathogenicity. , 2011, The Biochemical journal.

[64]  T. Arimoto,et al.  Surface Lipoprotein PpiA of Streptococcus mutans Suppresses Scavenger Receptor MARCO-Dependent Phagocytosis by Macrophages , 2011, Infection and Immunity.

[65]  G. Liakopoulos,et al.  Gene Expression and Biochemical Characterization of Azotobacter vinelandii Cyclophilins and Protein Interaction Studies of the Cytoplasmic Isoform with dnaK and lpxH , 2011, Journal of Molecular Microbiology and Biotechnology.

[66]  Michael F. Seidl,et al.  Identification of Hyaloperonospora arabidopsidis Transcript Sequences Expressed during Infection Reveals Isolate-Specific Effectors , 2011, PloS one.

[67]  Feng Yang,et al.  CYP1, a hypovirus-regulated cyclophilin, is required for virulence in the chestnut blight fungus. , 2011, Molecular plant pathology.

[68]  W. Kühlbrandt,et al.  Cyclophilin D links programmed cell death and organismal aging in Podospora anserina , 2010, Aging cell.

[69]  X. Xuan,et al.  Toxoplasma gondii Cyclophilin 18 Regulates the Proliferation and Migration of Murine Macrophages and Spleen Cells , 2010, Clinical and Vaccine Immunology.

[70]  E. Eisenmesser,et al.  Structural and Biochemical Characterization of the Human Cyclophilin Family of Peptidyl-Prolyl Isomerases , 2010, PLoS biology.

[71]  H. Yoon,et al.  Expression of yeast cyclophilin A (Cpr1) provides improved stress tolerance in Escherichia coli. , 2010, Journal of microbiology and biotechnology.

[72]  M. Helmer-Citterich,et al.  Cyclosporin A Treatment of Leishmania donovani Reveals Stage-Specific Functions of Cyclophilins in Parasite Proliferation and Viability , 2010, PLoS neglected tropical diseases.

[73]  H. Yoon,et al.  A cyclophilin A CPR1 overexpression enhances stress acquisition in Saccharomyces cerevisiae , 2010, Molecules and cells.

[74]  C. Clayton,et al.  The trypanosome Pumilio-domain protein PUF7 associates with a nuclear cyclophilin and is involved in ribosomal RNA maturation , 2010, FEBS letters.

[75]  H. Yoon,et al.  Decarbonylated cyclophilin A Cpr1 protein protects Saccharomyces cerevisiae KNU5377Y when exposed to stress induced by menadione , 2010, Cell Stress and Chaperones.

[76]  G. von Samson-Himmelstjerna,et al.  In silico analysis of the cyclophilin repertoire of apicomplexan parasites , 2009, Parasites & Vectors.

[77]  V. DelVecchio,et al.  Differential composition of culture supernatants from wild-type Brucella abortus and its isogenic virB mutants , 2009, Archives of Microbiology.

[78]  P. Gan,et al.  Characterization of cyclophilin-encoding genes in Phytophthora , 2009, Molecular Genetics and Genomics.

[79]  E. Eisenmesser,et al.  Structural, Biochemical, and in Vivo Characterization of the First Virally Encoded Cyclophilin from the Mimivirus , 2007, Journal of Molecular Biology.

[80]  N. Cianciotto,et al.  A Legionella pneumophila Peptidyl-Prolyl cis-trans Isomerase Present in Culture Supernatants Is Necessary for Optimal Growth at Low Temperatures , 2007, Applied and Environmental Microbiology.

[81]  Trevor J Pemberton,et al.  Identification and comparative analysis of sixteen fungal peptidyl-prolyl cis/trans isomerase repertoires , 2006, BMC Genomics.

[82]  A. Bell,et al.  Peptidyl-prolyl cis-trans isomerases (immunophilins) and their roles in parasite biochemistry, host-parasite interaction and antiparasitic drug action. , 2006, International journal for parasitology.

[83]  G. Folkers,et al.  The crystal structure of Aspergillus fumigatus cyclophilin reveals 3D domain swapping of a central element. , 2006, Structure.

[84]  S. Hammerschmidt,et al.  The Streptococcal Lipoprotein Rotamase A (SlrA) Is a Functional Peptidyl-prolyl Isomerase Involved in Pneumococcal Colonization* , 2006, Journal of Biological Chemistry.

[85]  R. Zardoya,et al.  Actinobacteria Cyclophilins: Phylogenetic Relationships and Description of New Class- and Order-Specific Paralogues , 2006, Journal of Molecular Evolution.

[86]  L. Kay,et al.  Intrinsic dynamics of an enzyme underlies catalysis , 2005, Nature.

[87]  S. Barik,et al.  A Novel Class of Dual-family Immunophilins* , 2005, Journal of Biological Chemistry.

[88]  Ping Wang,et al.  The cyclophilins , 2005, Genome Biology.

[89]  Joseph Heitman,et al.  Cyclophilin A Is Localized to the Nucleus and Controls Meiosis in Saccharomyces cerevisiae , 2005, Eukaryotic Cell.

[90]  J. Andersen,et al.  Structural Determinants of the Anti-HIV Activity of a CCR5 Antagonist Derived from Toxoplasma gondii* , 2004, Journal of Biological Chemistry.

[91]  S. Mowbray,et al.  X-ray structure of peptidyl-prolyl cis-trans isomerase A from Mycobacterium tuberculosis. , 2004, European journal of biochemistry.

[92]  A. Chakraborty,et al.  Isomerase-independent chaperone function of cyclophilin ensures aggregation prevention of adenosine kinase both in vitro and under in vivo conditions. , 2004, Biochemistry.

[93]  C. Levis,et al.  Cyclophilin A and calcineurin functions investigated by gene inactivation, cyclosporin A inhibition and cDNA arrays approaches in the phytopathogenic fungus Botrytis cinerea , 2003, Molecular microbiology.

[94]  J. Andersen,et al.  Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii. , 2003, Blood.

[95]  P. Faou,et al.  A novel binding protein for a member of CyP40-type Cyclophilins: N.crassa CyPBP37, a growth and thiamine regulated protein homolog to yeast Thi4p. , 2003, Journal of molecular biology.

[96]  J. Luban,et al.  Cyclophilin A Peptidyl-Prolyl Isomerase Activity Promotes Zpr1 Nuclear Export , 2002, Molecular and Cellular Biology.

[97]  K. Gould,et al.  Proteomics Analysis Reveals Stable Multiprotein Complexes in Both Fission and Budding Yeasts Containing Myb-Related Cdc5p/Cef1p, Novel Pre-mRNA Splicing Factors, and snRNAs , 2002, Molecular and Cellular Biology.

[98]  N. Talbot,et al.  A Magnaporthe grisea Cyclophilin Acts as a Virulence Determinant during Plant Infection Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010389. , 2002, The Plant Cell Online.

[99]  C. Brown,et al.  Cyclophilin A Mediates Vid22p Function in the Import of Fructose-1,6-bisphosphatase into Vid Vesicles* , 2001, The Journal of Biological Chemistry.

[100]  P. Folk,et al.  Cyclophilins of a novel subfamily interact with SNW/SKIP coregulator in Dictyostelium discoideum and Schizosaccharomyces pombe. , 2001, Biochimica et biophysica acta.

[101]  J. Heitman,et al.  Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans , 2001, EMBO reports.

[102]  J. Heitman,et al.  Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3–Rpd3 histone deacetylase , 2000, The EMBO journal.

[103]  G. Fischer,et al.  Enzymes that catalyse the restructuring of proteins. , 2000, Current opinion in structural biology.

[104]  J. Heitman,et al.  Molecular cloning and characterization of Aspergillus nidulans cyclophilin B. , 1999, Fungal genetics and biology : FG & B.

[105]  T. Maruyama,et al.  Gene for a cyclophilin-type peptidyl-prolyl cis-trans isomerase from a halophilic archaeum, Halobacterium cutirubrum. , 1997, Gene.

[106]  N. Hugouvieux-Cotte-Pattat,et al.  Characterization of a periplasmic peptidyl-prolyl cis-trans isomerase in Erwinia chrysanthemi. , 1997, FEMS microbiology letters.

[107]  K Dolinski,et al.  All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[108]  D. Ollis,et al.  Crystal structure of cytoplasmic Escherichia coli peptidyl-prolyl isomerase: evidence for decreased mobility of loops upon complexation. , 1997, Journal of molecular biology.

[109]  S. Lindquist,et al.  A Cyclophilin Function in Hsp90-Dependent Signal Transduction , 1996, Science.

[110]  J. Hacker,et al.  A cyclophilin‐like peptidyl‐prolyl cis/trans isomerase from Legionella pneumophila – characterization, molecular cloning and overexpression , 1996, Molecular microbiology.

[111]  M. Marahiel,et al.  Cold shock stress-induced proteins in Bacillus subtilis , 1996, Journal of bacteriology.

[112]  M. Marahiel,et al.  Peptidyl-prolyl cis-trans isomerase of Bacillus subtilis: identification of residues involved in cyclosporin A affinity and catalytic efficiency. , 1996, Biochemistry.

[113]  M. Kleerebezem,et al.  Characterization of an Escherichia coli rotA mutant, affected in periplasmic peptidyl‐prolyl cis/trans isomerase , 1995, Molecular microbiology.

[114]  A. Matouschek,et al.  Cyclophilin catalyzes protein folding in yeast mitochondria. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[115]  K. Hellingwerf,et al.  A gene of Acinetobacter calcoaceticus BD413 encodes a periplasmic peptidyl-prolyl cis-trans isomerase of the cyclophilin sub-class that is not essential for growth. , 1994, Biochimica et biophysica acta.

[116]  J. Heitman,et al.  Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[117]  C. Walsh,et al.  Three-dimensional solution structure of Escherichia coli periplasmic cyclophilin. , 1994, Biochemistry.

[118]  M. Marahiel,et al.  Cloning and characterization of ppiB, a Bacillus subtilis gene which encodes a cyclosporine A‐sensitive peptidyl‐prolyl cis‐trans isomerase , 1994, Molecular microbiology.

[119]  K. Nagashima,et al.  Cyclosporin A sensitive peptidyl-prolyl cis-trans isomerase in a halophilic archaeum, Halobacterium cutirubrum. , 1994, Biochemical and biophysical research communications.

[120]  J. Sambrook,et al.  Proline isomerases function during heat shock. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[121]  A. Kaplan,et al.  A Cyanobacterial Gene Encoding Peptidyl-Prolyl cis-trans Isomerase. , 1992, Plant physiology.

[122]  A. Pahl,et al.  Streptomycetes possess peptidyl‐prolyl cis‐trans isomerases that strongly resemble cyclophilins from eukaryotic organisms , 1992, Molecular microbiology.

[123]  J. Macdonald,et al.  Structural and functional characterization of Escherichia coli peptidyl-prolyl cis-trans isomerases. , 1992, European journal of biochemistry.

[124]  P. Kurki.  [Cyclosporin treatment]. , 1992, Duodecim; laaketieteellinen aikakauskirja.

[125]  Stuart L. Schreiber,et al.  Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes , 1991, Cell.

[126]  N. Takahashi,et al.  Two distinct forms of peptidylprolyl-cis-trans-isomerase are expressed separately in periplasmic and cytoplasmic compartments of Escherichia coli cells. , 1991, Biochemistry.

[127]  J. Liu,et al.  Human and Escherichia coli cyclophilins: sensitivity to inhibition by the immunosuppressant cyclosporin A correlates with a specific tryptophan residue. , 1991, Biochemistry.

[128]  W. Neupert,et al.  Sensitivity to cyclosporin A is mediated by cyclophilin in Neurospora crassa and Saccharomyces cerevisiae , 1989, Nature.

[129]  T. Kiefhaber,et al.  Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins , 1989, Nature.

[130]  T. Hayano,et al.  Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin , 1989, Nature.