Mechanisms of topoisomerase I inhibition by anticancer drugs.
暂无分享,去创建一个
K W Kohn | K. Kohn | Y. Pommier | Y Pommier | A Tanizawa | A. Tanizawa
[1] K. Kohn,et al. Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[2] R. Weichselbaum,et al. Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents , 1995, Nature.
[3] Y. Pommier,et al. Eukaryotic DNA topoisomerases I. , 1995, Biochimica et biophysica acta.
[4] Y. Cheng,et al. Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity. , 1995, Molecular pharmacology.
[5] E. Louis,et al. Sgs1: A eukaryotic homolog of E. coil RecQ that interacts with topoisomerase II in vivo and is required for faithful chromosome segregation , 1995, Cell.
[6] L. Liu,et al. Cell cycle-specific and transcription-related phosphorylation of mammalian topoisomerase I. , 1995, Experimental cell research.
[7] D. Toppmeyer,et al. A phase I and pharmacokinetic study of a new camptothecin derivative, 9-aminocamptothecin. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.
[8] M. Wani,et al. Camptothecin and taxol: discovery to clinic--thirteenth Bruce F. Cain Memorial Award Lecture. , 1995, Cancer research.
[9] D. Averbeck,et al. Comparison of the effects of DNA topoisomerase inhibitors on lymphoblasts from normal and Fanconi anemia donors. , 1994, Mutation research.
[10] S Gangloff,et al. The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase , 1994, Molecular and cellular biology.
[11] A. Fornace,et al. The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia. , 1994, Cancer research.
[12] J. M. Murcia,et al. Poly(ADP-ribose) polymerase: a molecular nick-sensor. , 1994, Trends in biochemical sciences.
[13] M. Kastan,et al. DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways , 1994, Molecular and cellular biology.
[14] R. Roeder,et al. Identification of human DNA topoisomerase I as a cofactor for activator-dependent transcription by RNA polymerase II. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[15] L. Liu,et al. Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system. , 1993, Cancer research.
[16] S. Ellard,et al. Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: phenotypic similarities to ataxia telangiectasia and Fanconi's anaemia cells. , 1993, Carcinogenesis.
[17] Y. Pommier,et al. Dual topoisomerase I and II inhibition by intoplicine (RP-60475), a new antitumor agent in early clinical trials. , 1993, Molecular pharmacology.
[18] D. Reinberg,et al. DNA topoisomerase I is involved in both repression and activation of transcription , 1993, Nature.
[19] R. Slebos,et al. Loss of a p53-associated G1 checkpoint does not decrease cell survival following DNA damage. , 1993, Cancer research.
[20] H. Strutt,et al. Hypersensitivity of Cockayne's syndrome cells to camptothecin is associated with the generation of abnormally high levels of double strand breaks in nascent DNA. , 1993, Cancer research.
[21] S. Korsmeyer,et al. Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis. , 1993, Cancer research.
[22] M. Poot,et al. DNA topoisomerases and the DNA lesion in human genetic instability syndromes. , 1993, Toxicology letters.
[23] Y. Pommier,et al. Sequential administration of camptothecin and etoposide circumvents the antagonistic cytotoxicity of simultaneous drug administration in slowly growing human colon carcinoma HT-29 cells. , 1992, European journal of cancer.
[24] Y. Pommier,et al. Topoisomerase I alteration in a camptothecin-resistant cell line derived from Chinese hamster DC3F cells in culture. , 1992, Cancer research.
[25] D. Kufe,et al. Camptothecin and its derivatives induce expression of the c-jun protooncogene in human myeloid leukemia cells. , 1991, Cancer research.
[26] K. Kohn,et al. Local base sequence preferences for DNA cleavage by mammalian topoisomerase II in the presence of amsacrine or teniposide. , 1991, Nucleic acids research.
[27] G. Hofmann,et al. Synergistic cell killing by ionizing radiation and topoisomerase I inhibitor topotecan (SK&F 104864). , 1991, Cancer research.
[28] J. Riou,et al. Inhibition of eukaryotic DNA topoisomerase I and II activities by indoloquinolinedione derivatives. , 1991, Molecular pharmacology.
[29] K W Kohn,et al. Effect of local DNA sequence on topoisomerase I cleavage in the presence or absence of camptothecin. , 1991, The Journal of biological chemistry.
[30] T. Andoh,et al. Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives. , 1991, Cancer research.
[31] P. Jeggo,et al. Cross-sensitivity of γ-ray-sensitive hamster mutants to cross-linking agents , 1991 .
[32] H. Kuga,et al. Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. , 1991, Cancer research.
[33] K. Kohn,et al. S-phase population analysis does not correlate with the cytotoxicity of camptothecin and 10,11-methylenedioxycamptothecin in human colon carcinoma HT-29 cells. , 1991, Cancer communications.
[34] H. Strutt,et al. Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA. , 1991, Nucleic acids research.
[35] H. Nakano,et al. Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus. , 1991, Biochemistry.
[36] K S Sellins,et al. Hyperthermia induces apoptosis in thymocytes. , 1991, Radiation research.
[37] U. Mortensen,et al. Eukaryotic topoisomerase I-DNA interaction is stabilized by helix curvature. , 1991, Nucleic acids research.
[38] S. Kaufmann,et al. Antagonism between camptothecin and topoisomerase II-directed chemotherapeutic agents in a human leukemia cell line. , 1991, Cancer research.
[39] J. Boehm,et al. Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity , 1991 .
[40] K. Kohn,et al. Local sequence requirements for DNA cleavage by mammalian topoisomerase II in the presence of doxorubicin. , 1990, Nucleic acids research.
[41] R. Hertzberg,et al. Irreversible trapping of the DNA-topoisomerase I covalent complex. Affinity labeling of the camptothecin binding site. , 1990, The Journal of biological chemistry.
[42] L. Liu,et al. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. , 1990, Cancer research.
[43] N. Saijo,et al. Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance. , 1990, Cancer research.
[44] A. Amadei,et al. Regulation of the function of eukaryotic DNA topoisomerase I: analysis of the binding step and of the catalytic constants of topoisomerization as a function of DNA topology. , 1990, Biochemistry.
[45] P. Caron,et al. The role of DNA topoisomerases in recombination and genome stability: A double-edged sword? , 1990, Cell.
[46] K. Lund,et al. Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitro. , 1990, The Journal of biological chemistry.
[47] K. Kohn,et al. Effects of morpholinyl doxorubicins, doxorubicin, and actinomycin D on mammalian DNA topoisomerases I and II. , 1990, Molecular pharmacology.
[48] C. Bendixen,et al. Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription. , 1990, Biochemistry.
[49] Y. Pommier,et al. Phosphorylation of mammalian DNA topoisomerase I and activation by protein kinase C. , 1990, The Journal of biological chemistry.
[50] U. Mortensen,et al. Distamycin inhibition of topoisomerase I-DNA interaction: a mechanistic analysis. , 1990, Nucleic acids research.
[51] R. Snapka,et al. Exposure to camptothecin breaks leading and lagging strand simian virus 40 DNA replication forks. , 1990, Biochemical and biophysical research communications.
[52] A. Richter,et al. Expression of the topoisomerase I gene in serum stimulated human fibroblasts. , 1990, Biochimica et biophysica acta.
[53] T. Furuta,et al. Metabolism and pharmacokinetics of the camptothecin analogue CPT-11 in the mouse. , 1990, Cancer research.
[54] J. Thacker,et al. DNA-break repair, radioresistance of DNA synthesis, and camptothecin sensitivity in the radiation-sensitive irs mutants: comparisons to ataxia-telangiectasia cells. , 1990, Mutation research.
[55] K. Kohn,et al. Plant antitumor agents. 29. Synthesis and biological activity of ring D and ring E modified analogues of camptothecin. , 1990, Journal of medicinal chemistry.
[56] R. Herrera,et al. Rapid induction of c-fos transcription reveals quantitative linkage of RNA polymerase II and DNA topoisomerase I enzyme activities , 1990, Cell.
[57] J. Champoux. 6 Mechanistic Aspects of Type-I Topoisomerases , 1990 .
[58] G. Gianfranceschi,et al. Phosphorylation sites for type N II protein kinase in DNA-topoisomerase I from calf thymus. , 1990, The International journal of biochemistry.
[59] K. Kohn,et al. 10,11-Methylenedioxycamptothecin, a topoisomerase I inhibitor of increased potency: DNA damage and correlation to cytotoxicity in human colon carcinoma (HT-29) cells. , 1990, Cancer communications.
[60] D. Samuels,et al. Protein kinase C phosphorylates DNA topoisomerase I , 1989, FEBS letters.
[61] Y. Pommier,et al. Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells. , 1989, Cancer research.
[62] J. Wang,et al. Expression of human DNA topoisomerase I in yeast cells lacking yeast DNA topoisomerase I: restoration of sensitivity of the cells to the antitumor drug camptothecin. , 1989, Cancer research.
[63] J. Champoux,et al. The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I. , 1989, Nucleic acids research.
[64] P. Kroeger,et al. Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene. , 1989, Nucleic acids research.
[65] A. Amadei,et al. In vitro preferential topoisomerization of bent DNA. , 1989, Nucleic acids research.
[66] L. Liu,et al. Poly(ADP-ribose)-mediated post-translational modification of chromatin-associated human topoisomerase I. Inhibitory effects on catalytic activity. , 1989, The Journal of biological chemistry.
[67] K. Kohn,et al. Protein-linked DNA strand breaks induced in mammalian cells by camptothecin, an inhibitor of topoisomerase I. , 1989, Cancer research.
[68] L. Liu,et al. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. , 1989, Cancer research.
[69] S. Chatterjee,et al. Mutant cells defective in poly(ADP-ribose) synthesis due to stable alterations in enzyme activity or substrate availability. , 1989, Experimental cell research.
[70] L. Liu,et al. DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues. , 1989, Cancer research.
[71] U. Mortensen,et al. Interactions between eukaryotic DNA topoisomerase I and a specific binding sequence. , 1989, The Journal of biological chemistry.
[72] R. Hertzberg,et al. On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex. , 1989, Biochemistry.
[73] R. Hertzberg,et al. In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone. , 1989, Cancer research.
[74] J. Wang,et al. Peptide sequencing and site-directed mutagenesis identify tyrosine-727 as the active site tyrosine of Saccharomyces cerevisiae DNA topoisomerase I. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[75] K. Kohn,et al. Structure-activity study of the actions of camptothecin derivatives on mammalian topoisomerase I: evidence for a specific receptor site and a relation to antitumor activity. , 1989, Cancer research.
[76] P. Cerutti,et al. ADP-ribosylation of ADPR-transferase and topoisomerase I in intact mouse epidermal cells JB6. , 1989, Biochemistry.
[77] R. Hertzberg,et al. Modification of the hydroxy lactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity. , 1989, Journal of medicinal chemistry.
[78] J. Champoux,et al. Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating molecules , 1989, Molecular and cellular biology.
[79] P. Smith,et al. Enhanced sensitivity to camptothecin in ataxia-telangiectasia cells and its relationship with the expression of DNA topoisomerase I. , 1989, International journal of radiation biology.
[80] J. Champoux,et al. The effects of camptothecin on the reaction and the specificity of the wheat germ type I topoisomerase. , 1989, The Journal of biological chemistry.
[81] S. Chatterjee,et al. Camptothecin hypersensitivity in poly(adenosine diphosphate-ribose) polymerase-deficient cell lines. , 1989, Cancer communications.
[82] K. Kohn,et al. Topoisomerase I interaction with SV40 DNA in the presence and absence of camptothecin. , 1988, Nucleic acids research.
[83] R. Sternglanz,et al. Evidence that DNA topoisomerase I is necessary for the cytotoxic effects of camptothecin. , 1988, Molecular pharmacology.
[84] R. Hertzberg,et al. Camptothecin-resistant mutants of Chinese hamster ovary cells containing a resistant form of topoisomerase I. , 1988, Cancer research.
[85] J. Wang,et al. DNA topoisomerase-targeting antitumor drugs can be studied in yeast. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[86] C. Perez-stable,et al. Enrichment and depletion of Hela topoisomerase I recognition sites among specific types of DNA elements. , 1988, Nucleic acids research.
[87] R. Knippers,et al. Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks , 1988, Molecular and cellular biology.
[88] E. Di Mauro,et al. Eukaryotic DNA topoisomerase I reaction is topology dependent. , 1988, Nucleic acids research.
[89] L. Bolund,et al. Sequence-dependent effect of camptothecin on human topoisomerase I DNA cleavage. , 1988, Journal of molecular biology.
[90] R. Benbow,et al. Regulation of Xenopus laevis DNA topoisomerase I activity by phosphorylation in vitro. , 1988, Biochemistry.
[91] L. Liu,et al. Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. , 1988, Cancer research.
[92] L. Bolund,et al. Characterization of a camptothecin-resistant human DNA topoisomerase I. , 1988, The Journal of biological chemistry.
[93] M. Muller,et al. Stabilization of type I topoisomerase-DNA covalent complexes by actinomycin D. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[94] V. Culotta,et al. Sites of topoisomerase I action on X. laevis ribosomal chromatin: Transcriptionally active rDNA has an ∼200 bp repeating structure , 1988, Cell.
[95] W. Earnshaw,et al. Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[96] J. Wang,et al. Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[97] T. Tanaka,et al. Antitumor activity of 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothec in, a novel water-soluble derivative of camptothecin, against murine tumors. , 1987, Cancer research.
[98] G. Manikumar,et al. Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring A substituted camptothecin analogues. Structure-activity correlations. , 1987, Journal of medicinal chemistry.
[99] G. Schütz,et al. Camptothecin-induced in vivo topoisomerase I cleavages in the transcriptionally active tyrosine aminotransferase gene , 1987, Cell.
[100] Y. Pommier,et al. DNA unwinding and inhibition of mouse leukemia L1210 DNA topoisomerase I by intercalators. , 1987, Nucleic acids research.
[101] Y. Suzuki,et al. Characterization of a mammalian mutant with a camptothecin-resistant DNA topoisomerase I. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[102] J. Wang. Recent studies of DNA topoisomerases. , 1987, Biochimica et biophysica acta.
[103] H. Blöcker,et al. Sequence specificity of DNA topoisomerase I in the presence and absence of camptothecin. , 1987, The EMBO journal.
[104] S. Jacob,et al. Role of DNA topoisomerase I in the transcription of supercoiled rRNA gene. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[105] S. Crooke,et al. Relationship between the intracellular effects of camptothecin and the inhibition of DNA topoisomerase I in cultured L1210 cells. , 1987, Cancer research.
[106] L. Liu,et al. Roles of DNA topoisomerases in simian virus 40 DNA replication in vitro. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[107] S. Elgin,et al. Localization of specific topoisomerase I interactions within the transcribed region of active heat shock genes by using the inhibitor camptothecin , 1987, Molecular and cellular biology.
[108] D. Kroll,et al. Camptothecin inhibits hsp 70 heat-shock transcription and induces DNA strand breaks in hsp 70 genes in Drosophila. , 1987, NCI monographs : a publication of the National Cancer Institute.
[109] R. Snapka. Topoisomerase inhibitors can selectively interfere with different stages of simian virus 40 DNA replication. , 1986, Molecular and cellular biology.
[110] J. Champoux,et al. The role of single-strand breaks in the catenation reaction catalyzed by the rat type I topoisomerase. , 1986, The Journal of biological chemistry.
[111] Y. Sugiura,et al. Photosensitive DNA cleavage and phage inactivation by copper(II)-camptothecin. , 1986, Biochemistry.
[112] R. Hertzberg,et al. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. , 1985, The Journal of biological chemistry.
[113] M. Goodenough,et al. Topoisomerase I phosphorylation in vitro and in rapidly growing Novikoff hepatoma cells. , 1985, The EMBO journal.
[114] J. Jongstra-Bilen,et al. Inhibition of calf thymus type II DNA topoisomerase by poly(ADP‐ribosylation). , 1985, The EMBO journal.
[115] O. Westergaard,et al. A high affinity topoisomerase I binding sequence is clustered at DNAase I hypersensitive sites in tetrahymena R-chromatin , 1985, Cell.
[116] M. Muller,et al. Eukaryotic type I topoisomerase is enriched in the nucleolus and catalytically active on ribosomal DNA. , 1985, The EMBO journal.
[117] M. Fukada. Action of camptothecin and its derivatives on deoxyribonucleic acid. , 1985, Biochemical pharmacology.
[118] M. Muller. Quantitation of eukaryotic topoisomerase I reactivity with DNA. Preferential cleavage of supercoiled DNA. , 1985, Biochimica et biophysica acta.
[119] J. Champoux,et al. Breakage of single-stranded DNA by eukaryotic type 1 topoisomerase occurs only at regions with the potential for base-pairing. , 1984, Journal of molecular biology.
[120] J. Wang,et al. Drosophila DNA topoisomerase I is associated with transcriptionally active regions of the genome. , 1984, Proceedings of the National Academy of Sciences of the United States of America.
[121] R. Burgess,et al. Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA. , 1984, Nucleic acids research.
[122] B. Olivera,et al. Poly(ADP-ribosylation) of DNA topoisomerase I from calf thymus. , 1984, The Journal of biological chemistry.
[123] M. C. McElwain,et al. Poly(ADP-ribosylation) of DNA topoisomerase I: a nuclear response to DNA-strand interruptions. , 1984, Cold Spring Harbor symposia on quantitative biology.
[124] L. Thompson,et al. Poly (ADP-ribosylation) and DNA topoisomerase I in different cell lines. , 1984, Advances in experimental medicine and biology.
[125] Y. Tse‐Dinh,et al. Virus- and cell-encoded tyrosine protein kinases inactivate DNA topoisomerases in vitro , 1984, Nature.
[126] P. Mandel,et al. DNA topoisomerase I from calf thymus is inhibited in vitro by poly(ADP-ribosylation). , 1983, European journal of biochemistry.
[127] B. Olivera,et al. Poly(ADP-ribosylation) of a DNA topoisomerase. , 1983, The Journal of biological chemistry.
[128] H. Busch,et al. Phosphorylation of purified Novikoff hepatoma topoisomerase I. , 1983, Biochemical and biophysical research communications.
[129] M. Duguet,et al. DNA topoisomerases from rat liver: physiological variations. , 1983, Nucleic acids research.
[130] L. Liu,et al. Intra- and intermolecular strand transfer by HeLa DNA topoisomerase I. , 1982, The Journal of biological chemistry.
[131] K. Kohn,et al. Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino) methanesulfon-m-anisidide and adriamycin. , 1981, Biochemistry.
[132] J. Champoux,et al. The effect of salt on the binding of the eucaryotic DNA nicking-closing enzyme to DNA and chromatin. , 1981, Biochimica et biophysica acta.
[133] J. Champoux. DNA is linked to the rat liver DNA nicking-closing enzyme by a phosphodiester bond to tyrosine. , 1981, The Journal of biological chemistry.
[134] J. Wang,et al. Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA. , 1980, The Journal of biological chemistry.
[135] Hutchinson Cr,et al. Prodrug analogues of the antitumor alkaloid camptothecin. , 1979 .
[136] J. Champoux. Mechanism of the reaction catalyzed by the DNA untwisting enzyme: attachment of the enzyme to 3'-terminus of the nicked DNA. , 1978, Journal of molecular biology.
[137] J. Champoux. Strand breakage by the DNA untwisting enzyme results in covalent attachment of the enzyme to DNA. , 1977, Proceedings of the National Academy of Sciences of the United States of America.
[138] J. Champoux. Evidence for an intermediate with a single-strand break in the reaction catalyzed by the DNA untwisting enzyme. , 1976, Proceedings of the National Academy of Sciences of the United States of America.
[139] M. Horwitz,et al. Effects of camptothecin on the breakage and repair of DNA during the cell cycle. , 1973, Cancer research.
[140] L. Li,et al. Action of camptothecin on mammalian cells in culture. , 1972, Cancer research.
[141] K. Kohn,et al. Effects of deoxyribonucleic acid-reactive drugs on ribonucleic acid synthesis in leukemia L1210 cells. , 1972, Molecular pharmacology.
[142] D. Kessel,et al. Camptothecin effects on DNA synthesis in murine leukemia cells. , 1972, Biochimica et biophysica acta.
[143] J. Warner,et al. Ribosome formation is blocked by camptothecin, a reversible inhibitor of RNA synthesis. , 1971, Proceedings of the National Academy of Sciences of the United States of America.
[144] M. Horwitz,et al. Intracellular degradation of HeLa and adenovirus type 2 DNA induced by camptothecin. , 1971, Biochemical and biophysical research communications.
[145] A. Grollman,et al. Studies on camptothecin. I. Effects of nucleic acid and protein synthesis. , 1971, Molecular pharmacology.
[146] D. Kessel,et al. Effects of camptothecin on RNA synthesis in leukemia L1210 cells. , 1971, Biochimica et biophysica acta.